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P A G E 1

Information Pack

" BRINGING IDEAS TO YOU FROM ALL OF US WITH PANCREATITIS "

We are a registered charity

(Number 102447) and as such

have our costs to cover, we

would appreciate a contribution

of £2 for this information and

this can be in the form of

stamps. However, telephone

advice is FREE. Just phone and

leave your name and number on

the answer machine and we will

call you back.

You have been sent this

pack following your initial enquiry

from the Pancreatitis Supporters

Network. You may have either

Acute Chronic or Cancer of the

Pancreas You may have a partner

with the condition or have a

friend or general interest in the

same. For this reason the information

has been kept as general

as possible.

More specific information

has been included in the set

of THREE booklets on the aforementioned

versions of this condition.

O u r a d d r e s s i s :

T h e P a n c r e a t i t i s S u p p o r t e r s

N e t w o r k

P O B o x 8 9 3 8

B i r m i n g h a m B 1 3 9 H S

P L E A S E N O T E :

T h e i n f o r m a t i o n c o n t a i n e d

w i t h i n i s n o t n e c e s s a r i l y t h e o p i n -

i o n o f t h e N e t w o r k a n d A L L m e d -

i c a l i n f o r m a t i o n s h o u l d b e

d i s c u s s e d w i t h y o u r o w n G P o r

C o n s u l t a n t b e f o r e e m b a r k i n g o n

a n y c h a n g e s i n m e d i c a t i o n .

Information Pack produced by the

Pancreatitis Supporters Network. Tel. 0 P o s s i b l e D r u g s y

o u m a y b e

p r e s c r i b e d w h e n y o u h a v e b e e n

d i a g n o s e d a s h a v i n g P a n c r e a t i t i s .

T h e f o l l o w i n g i s b y n o m e a n s a n

e x h a u s t i v e l i s t , r a t h e r a g u i d e t o

w h a t y o u m a y b e p r e s c r i b e d . T h i s

w i l l v a r y g r e a t l y f o r m i n d i v i d u a l t o

i n d i v i d u a l .

E N Z Y M E R E P L A C E M E N T D R U G S

P a n c r e a s e C i l a g

P a n c r e x V C a p s u l e s ' 1 2 5 '

P a n c r e x V F o r t e T a b l e t s

P a n c r e x V T a b l e t s

P a n c r e x V C a p s u l e s

P a n c r e x V P o w d e r

P a n c r e x G r a n u l e s

C r e o n

N u t r i z y m G R M e r c k

N u t r i z y m 2 2

D R U G S F O R P A I N R E L I E F

M S T C o n t i n u s N a p p

O r o m o r p h

P a r a c e t o m o l

D i h y d r o c o d e i n e

I b u p r o f e n

D i s t a l g e s i c D i s t a

P A M E R G A N P 1 0 0

C O L P E R M I N

A c u p a n

X Y L O P R O C T A s t r a . ( G r e a t f o r t h e

r e l i e f o f t h e p a i n a n d d i s c o m f o r t

f r o m p i l e s ! T o t a l l y n u m b s t h e a r e a

a l l t o g e t h e r )

S y m p t o m s :

PAIN

N A U S E A A N D V O M I T I N G

L O S S O F A P P E T I T E

W E I G H T L O S S

S T E A T O R R H O E A ( P a s s i n g o f

loose, bulky, pale, smelly stools

Which are hard to flush away.)

M A L A I S E A N D L E T H A R G Y

D i a g n o s i s :

B L O O D T E S T S

S T O O L S A M P L E S

U L T R A S O U N D S C A N

C T S C A N ( C O M P U T E R I S E D

T O M O G R A P H Y S C A N )

E R C P ( E N D O S C O P I C R E T R O -

G R A D E C H O L A N G I O - P A N C R E A T O -

G R A M )

P E R C U T A N E O U S P A N C R E A T O -

G R A M

Treatment:

M E D I C A L - A l l e v i a t e t h e p a i n a n d

r e d u c e t h e w o r k l o a d o f t h e p a n c r e a s .

S U R G I C A L - t h e r e a r e n o g u a r a n -

tees about the success of the same.

T h e p a n c r e a s i s a r e m a r k a b l e

gland that secretes digestive juices into

the duodenum - the first part of the

intestine - to help us break down food

into the small molecules that can be

a b s o r b e d b y t h e b o d y . I t a l s o s e c r e t e s

insulin into the bloodstream to keep the

concentration of glucose in our blood

at the right level.

Once the inflammation starts, the

digestive enzymes of the pancreas are

not harmlessly contained within their

proper ducts and may start to " digest "

the pancreas itself causing further inf

l a m m a t i o n .

The agonising pain in the top of

t h e a b d o m e n i s u s u a l l y a c c o m p a n i e d

by vomiting and retching. The condition

is so severe it really needs expert attention

in hospital.

Brief introduction to the condition:

P A G E 2

....Except being told to eat no fat

where possible or keep it down to 2.0g

in any product (or below) and no alcohol

of any sort and dairy stuff to be

skimmed or non-fat or none at all, I was

not given any more advice.

I have found out for myself, just

recently, and often after such a lot of

acute pain, that the following foods

were obviously not helping me one bit

and causing years of pain.

This may be helpful news to other

members if included in the Newsletter

to come - I leave you to decide how to

present it.

1) I cannot digest any salad food

and have not eaten any this Summer (a

few tomatoes if boiled and de-skinned)

2) I cannot digest any citrus fruits

or had any fruits - apples etc. and just

occasionally raspberries, strawberries

etc.

3) All vegetables are OK so long

as they are cooked (never raw) and I

eat a lot of every kind.

4) I buy tinned soft fruit (mangoes

are super) and find this I can cope with

- supermarkets selections are not too

expensive and it is all fruit and no peel,

skin and pips - which are no good to

me!

....I am OK with all meats, fowl and

fish cooked any way and even bacon

grilled and the odd oven chip!

I am taking in a bit more fat like

biscuits, cake, chocolates, semiskimmed

milk and yoghurt etc. (but only

once a week).

I think Sanatogen powder, Glucose

powder and Luctulose are doing me a

lot of good!

_________________________

Yes, I cannot eat any Dairy food

only perhaps once a month, very little,

check when weekly shopping you do

not buy any food containing cheese

sauce, or sauces of any kind (very fat). I

always read labels on the back of packets

etc., if it contains more than 4g fat

put it back. Make your own soups, hot

or cold with lots of Pasta, Veg, sometimes

fruit. No cakes or goodies from

sweet shelf, but in-between have a go

at different cakes as a filler.

_____________________

Yes! This is me also! Have for 7

years been on non-fat or low-fat food:

Skimmed milk

Low-fat yoghurt

No cheese, biscuits,

cakes, chocolate, fat meat,

suet etc.

Had to be brain washed to read

every label on everything and if it was

above 2.0g fat content, don't buy it or

eat it!

___________________

I thought the enclosed might be of

interest to your members who, like me,

have to limit their fat intake from all

sources. to no more than 50g per week

(see next section - Editor). I tried them

and found they enlivened a salad and

they contain 1g per 100g instead of the

normal 24-30g. I wrote to the manufacturers

to get to know more about

other items in their low fat range, also

supplies.

(Response to above letter below -

Editor)

THE LOW FAT SNACK CO

1A Standard Road

London

NW10 6EX

Tel 0

Thank you for your recent letter

regarding our low fat snacks.

........The 99% Low Fat Potato Waffles

were launched by SAFEWAY.

......The BOOTS stores will be launching

two new products in the middle of October

which are called 'Shapers Very

Low Fat Pizza Pieces' and 'Shapers

Very Low Fat American Waffles'.

.......Another product is called 'Pasta

Snacks' (which is 50% lower in fat than

normal crisps) and we currently supply

to some of the SAINSBURY'S stores.

......WAITROSE have a similar product

called 'Spicy Tomato Pasta Crisps' and

'Garlic and Herb Pasta Crisps' and

ASDA also have a similar product

called

'Italian Style Snacks' - which are

under their own respective labels.

....Unfortunately we cannot supply

direct to the public.

_______________________

___

Members Letters on the subject of DIET.

Names withheld.

How can I modify my diet

and daily activities to help

treat Pancreatitis?

Submitted by The

Pancreatic Society of Great

Britain and Ireland.

The single most important

change that any sufferer from

chronic pancreatitis can make is

to stop drinking alcohol. Even if

your pancreatitis is not directly

caused by alcohol, it is likely that

drinking alcohol will harm the

pancreas because it stimulates

the production of a thick, sticky

pancreatic juice which tends to

clog the pancreatic ducts. This

adds to the drainage already

taking place in the pancreas. It

is probably also helpful to stop

smoking, because smoking

stresses the body's natural

defence mechanisms against

inflammation and may

contribute to the damage

occurring in the pancreas. A

well balanced diet is probably

helpful. You need not restrict

fatty food and in fact an

adequate intake of fat may help

to prevent weight loss. If you

have access to a dietician, you

should ask for advice on how to

maintain an intake of 100 grams

of fat and 100 grams of protein

each day. If this diet causes

symptoms such as diarrhoea or

looseness of stools it is better to

begin or increase the dose of

pancreatic enzyme supplements

rather than to cut down the

amount you are eating.

Can vitamin supplements help?

There is some evidence that

antioxidants help to protect

against inflammation in a wide

variety of diseases. There are

many vitamin preparations with

added antioxidants available

from chemists and Health Food

shops. These preparations will

certainly do no harm, and some

patients find their pain is less

severe or less frequent when

they are taking them. Look out

for formulations which contain

vitamin C, vitamin E and

Selenium.

P A G E 3

Written by D Broadfoot

FISTC, MCIM [Heavily edited by the

Editor!] The author is a Fellow of the

Institute of Scientific and Technical

Communicators and is also a Chartered

Consultant who is working alongside

two Bristol based doctors (AJR Mac-

and TW Coates) to help them

introduce a new method of pain relief

known as Transcutanous Spinal Electroanalgesia

(TSE for short), which is

now available at a Recommended Retail

Price of £169 + VAT from the manufacturers:

Advanced Pain Management Ltd

Suite 2, Saturn Centre

Challenge Way

Blackburn

Lancashire

BB1 5QB

Telephone 01254 661431

Fax/answerphone 01254

611429

Customer Support and Advice Line

01254 611430

The X-Pain machine is fundamentally

different to the well established

'TENS' machine and indeed has more

in common with the surgical technique

known as Spinal Cord (Dorsal Column)

Stimulation which has been practised

since 1967 to provide sufferers of

acute pain with measure of relief. Over

a 28 year period there has been no

indications of any possible side effects

related to the transmission of electricity

to this area.

In a major scientific breakthrough it

was discovered that when injury was

caused to any part of the body, spinal

cord interneurones (nerve cells) exhibit

a dramatic behavioural change which is

manifest by the production of c-FOS

protein. Once spinal cord interneurones

have been triggered by news of

an injury it would appear that these

nerve cells can subsequently remain

active for decades - and certainly long

after the injured part has healed completely.

As a result - and for reasons

which remain obscure - spinal cord

interneurones continue to send warning

messages to the brain which results in

millions of people suffering completely

unnecessary pain for much of their

lives.

Since electricity was first generated

and harnessed for use; its pain

relieving properties have been noted

and applied. Transcutanous Electrical

Nerve Stimulation (TENS) devices use

electrical stimulation to excite AB

[Editors note: the B here is the Greek

symbol] fibres in the area where pain is

experienced. They are arguably the

modern

equivalent of applying a hot water

bottle or ice pack (or healers hands) to

the apparent seat of the pain. All these

methods have an indirect effect on the

mechanism of the spinal cord interneurones.

However they have to be applied

to the correct place [My italics,

Editor], and therefore considerable skill

is required by the practitioner. When

pain is felt in the elbow, for example,

the tender region which requires treatment

may well be in the neck. If the

patient has two elbows in trouble and a

knee as well, several regions require

simultaneous treatment [rather like acupuncture:

Editor]. The only way to do

this was to aim for the spinal cord itself.

The key to success, the two Bristol

doctors discovered, was to determine

the precise intensity, frequency and

pulse width of electrical input to the

spinal area which would cause the spinal

cord interneurones to become dormant.

To achieve this they placed two

electrodes at the top and base of the

spine. Obviously, electrical energy

takes the most direct route and will

therefore flow parallel to the spine. The

electrical energy which reaches the

spinal cord is minute in terms of duration

so there is no stimulation of the

peripheral nerves in the area - in other

words, no localised pain.

The doctors then developed a

simple portable pulse generator which

the patient adjusts until a slight warming

sensation is felt. There is no discomfort.

One patient who was treated

by doctors using this device suffered

recurring spasms of pain for over 40

years since being struck in the stomach

by a rifle butt during the Korean

War. Other patients using the X-Pain

device have experienced almost immediate

relief where the original cause of

the injury has long healed or is 'on the

mend'. This is particularly true of neck

and back sufferers who have sufferers

an injury to their spine sometime previously.

The same is true to people who

suffer from painful limbs, stress aches,

migraines, headaches, postoperative

pains, arthritis, menstrual pains, and

'modern living' complaints such as repetitive

stress injury and M.E.

The X-Pain method of pain relief is

not an anaesthetic. It will not provide

relief for patients suffering from any

pain generating condition. Equally, it

will not hide the symptoms of heart

attacks, or angina, or where there is

inflammation to any organ brought

about by disease. Such pains are ongoing

and the signals will continue to

be sent to the brain regardless of any

TSE treatment. People who have a

medical condition which requires the

use of a Pacemaker or other implanted

electrical stimulator would not use the

TSE method - nor should pregnant

women, without first seeking medical

advice.

The closest competitor to the TSE

method is the widely practised method

of the 'TENS' machine. TSE offers five

distinct advantages when compared to

this form of treatment:-

An Answer to Pancreatitis Pain? Hormone Replacement

Therapy (HRT) Information

A request came in for

information concerning HRT

and Pancreatitis and this was

a response to this question

when I wrote to Professor

Neoptolemos (Please NOTE

this has been paraphrased):

" I know of no correlation

between HRT and Pancreatitis.

I am surprised to hear the

women on HRT are being

advised not to take it if they

have had attacks of acute

pancreatitis

........On balance, HRT is to

recommended for the majority,

if not all, of post menopausal

women. "

BENEFITS

1) Disability Living

Allowance

We recommend you

read CLAIMING

DISABILITY LIVING

ALLOWANCE available

from Disability Alliance,

88-94 Wentworth Street,

London E1 7SA. This

costs £4 per copy. £2.50

if individual on benefit.

2)ALL BENEFITS

ALSO they do a more

comprehensive book for

ALL UK Benefits

DISABILITY RIGHTS

HANDBOOK at a cost of

£11.50 postage free.

Telphone 0171 247

8776 (minicom also

available)

P A G E 4

.. Mr Neoptolemos MA MD FRCS

then arrived and introduced himself. He

described the various medical bodies

associated with pancreatitis:

Pancreatic Society of Britain and

Northern Ireland

British Society of Gastro Enterology

European Pancreatic Club

International Association of Pancreatology.

What are the various names and

forms of pancreatitis?

Described that there were two

main forms of pancreatitis those of

ACUTE and CHRONIC. The acute

tended to be a one off situation which

were generally caused by a particular

agent such as gallstones and the removal

of the cause removed the occurrence

of another attack except where

people ignored the cause of the attacks

which then triggered another acute

attack of pancreatitis. The Chronic was

a continuous occurrence of pancreatitis.

The pancreas tended to be diseased in

some way and the situation does not

improve but gets steadily worse over

the years.

What is Pancreas Divisum?

This he described as being

caused during the foetal development

of the pancreas which develops in a

front to back manner. The front bit

which develops towards the front of the

foetus is called ventral and the part that

develops towards the back of the foetus

is called dorsal. As the child develops

in the womb the other organs opus

these bits together so it folds in the

middle and joins up. Sometimes this

does not happen correctly and this is

called pancreas divisum. There then

could develop a stricture and this can

cause acute or chronic pancreatitis.

What is a pseudo cyst?

The pancreas is formed of lots of

little sacs of fluid each draining into

a bigger and bigger duct until they

reach the main duct for drainage. When

this fluid reached the duodenum it then

becomes activated. Sometimes due to

a blockage these can be activated

within the ducts of the pancreas which

then starts to eat at the tissue inside

the pancreas, rupturing or bleeding

may also occur. These usually heal on

their own.

Why do they (pseudo cysts) keep

filling up?

Sometimes they do not heal up on

their own and hence the reason they

then fill up again. This could be due to

a stricture developing later on for example.

Does alternative medicine help?

No. Though a lack of vitamins in

the diet of poorly fed individuals could

be helped with vitamin supplements.

Can diet help the prevention of

pseudo cysts?

No. though it should be noted that

small regular meals are better than

starving for the day and then

bingeing on a large meal in the

evening as this can bring on an

acute attack.

Extract of questions from the AGM of The Pancreatitis

Supporters Network April 1994

Pancreatic Society of Great

Britain and Ireland, Advice

for Patients

If in the UNITED

KINGDOM go to our

WEB ADDRESS:

www.pancreatitis.org

..uk and follow the link

to The Pancreatic

Society of Great Britain

and Iceland where you

can download ALL the

UK specialists,

Including one in Egypt.

The Pancreatic Society of

Great Britain and Ireland is

willing to help pancreatitis

sufferers who are having

difficulty in obtaining

specialist advice. If any

pancreatitis sufferer is

having difficulty obtaining

specialist advice, and they

would like information about

pancreatic specialists to

whom they could be

referred by their present

general practitioner or

hospital consultant write to:

Mr Charnley

Consultant Surgeon

Secretary to the PSGBI

Department of Surgery

Freeman Hospital

High Heaton

Newcastle-upon Tyne

NE7 7DN

The Secretary will supply the

names of specialists in an

appropriate geographical

area, but will not be able to

enter into correspondence

about specific general

conditions. The specialists

recommended will not

necessarily be members of

the Society. Please expect

at least a two to three month

delay before reply arrives.

Please note: There is

Internet access in all

UK Librarys

a) TSE provides longer lasting

relief from pain (possibly even permanent

relief in some cases).

B) The pain relieving benefits do

not diminish the more you use the TSE

machine.

c) TSE takes less time to use

(4 hours per week as opposed to

40 hours) and provides relief from pain

much sooner (8-20 minutes as opposed

to 40-60 minutes).

d) TSE provides simultaneous

relief of pain across the entire body

rather

than one place.

e) TSE does not require anatomical

knowledge to site the electrodes

correctly.

In summary, TSE would appear to

represent a major advance in pain

ther apy. (Editor in this article refers to

The Pancreatitis Supporters Network)

FOOTNOTE: The Pancreatitis Supporters

Network operates a long term

loan scheme to members who have

joined of these devices so that you can

try before you buy. For your membership

we will send a unit to you and the

only expense you have is the cost of

the pads and batteries. We will not ask

for it back but would hope that people

will return these if they do not work or if

they have enough money to purchase

one for themselves. The cost

of return of the machines is borne

by the charity as is the delivery.

As well as the TSE X-Pain 2000 machines

we are able to offer use of a

Medisense blood meter to those who

are diabetic, again only to joined members.

We would ask that you only request

one or other of these devices

and not both as at the moment we do

not have the resources to cope with

X-Pain Continued:

P A G E 5

(This information has been summaried

from TWO articles and vastly

edited and changed for ease of reading

and describes a new form of treatment

developed by Manchester Royal

Infirmary. It has NOTHING to do with

the Pancreatitis Supporters Network,

we are only including this for information.

ALL inquiries should be made in

the first instance to Margaret O'Brien,

Chairman of the MRI Support Group)

Causes of pancreatitis

There is accumulating evidence

that oxidant stress resulting from an

excess of pro-oxidant over anti-oxidant

has a key role in acute oedematous

pancreatitis as well as painful

exacerbation's of chronic disease.

Cytokines like platelet activation factor

(PAF) have also been shown to be

involved with development of the acute

disease in animal models, but it is likely

that the prime insult which triggers

pancreatitis is oxidant stress.

DEVELOPMENT OF ANTIOXIDANT

THERAPY

Background:

There is increasing evidence that

habitually poor diets render body organs

vulnerable to oxidative stress, and

hence tissue injury, when free radical

load exceeds antioxidant defence capability.

In general terms this load may

derive from such dissimilar sources as

ultraviolet light, substance abuse (for

example alcohol or cigarettes), and,

above all, environmental pollutants.

Antioxidant therapy?

From this, it would seem likely that

therapy with antioxidants should help

prevent pancreatitis. A randomised,

controlled, double-blind, double dummy,

crossover study from the Manchester

Royal Infirmary has shown this

to be the case.

Twenty patients with chronic pancreatitis

(8 idiopathic, 7 alcoholic and

5 idiopathic acute) entered the study in

which micro nutrients antioxidant therapy

was compared with placebo, each

for a 20 week period. Patients took

six tablets of selenium beta-CE

(Wassen International) and eight tablets

of methionine ( Medical Ltd) in

divided doses, giving a daily total of:

600mg organic selenium

9000 IU beta-carotene

0.54g vitamin C

270 IU vitamin E

2g methionine

Results: This was a thorough and

detailed study. The bare-boned results

were that while six patients had an

attack while on placebo, not one had

an attack while on active medication.

Pain scores were significantly lower on

active treatment (than) on placebo and

at baseline.

Benefits and costs:Treatment

would entail a maximum cost of 15

pounds a month a month (1990 prices),

with possibly a 50 percent reduction

after six months. This financial

outlay is small compared with the cost

in terms of the mortality, morbidity,

narcotic use, malnutrition and brittle

diabetes of near-total pancreatectomy.

Adverse effects and precautions:

Long-term observations have not

shown significant adverse effects in a

clinical experience of some 500 patients.

One subject developed symptoms

of schizophrenia two years after

starting on a dose of 4g methionine

per day in conjunction with other antioxidants.

In the light of a published

review which had exonerated methionine

from side-effects, unless given to

patients with chronic schizophrenia, it

was of interest to discover that the

patient's mother had committed suicide

against a background of schizophrenia

and that two maternal aunts

had suffered chronic depressive illness.

There has been no such problem

at MRI before or since.

Hypercarotenaemia has been a predictable

biochemical outcome in patients

treated with bio-antox because

the of extremely high bio availability of

beta-carote from this formulation compared

to the commercial " over the

counter " preparations with which the

clinical trials were done, and which

were used at the MRI until Bio-antox

became available. Hypercarotenaemia

has no clinical implications, Except for

possible cosmetic embarrassment,

and the preparation has now undergone

reformulation to avoid this. Careful

monitoring is advisable in patients

with organic brain syndromes, haemachromatosis,

renal failure and glucose-

6-phosphate-dehydrogenase

deficiency.

ANTIOXIDANT THERAPY FOR PANCREATITIS - BIO-ANTOX

For further information,

please contact the

following:

Margaret O'Brien

MRI Pancreatic

Patients Support

Group

Chairman,

01457 873859

PLEASE remember,

this is a HOME

TELEPHONE

NUMBER and have

due consideration at

the time when you

call.

Please Note: The

Pancreatitis Supporters

Network DOES NOT

promote any one form of

treatment over another

and all information in this

Newsletter is for

consultation with your

GP, Consultant or

Specialist.

NEWS FLASH

There is no doubt this

Information Pack will

become dated. We try

to update as soon as

possible but for all the

latest news please

Join. See last two

pages for Membership

Forms. All the latest

news will appear in the

Newsletters FIRST

then get posted on the

web at:

www.pancreatitis.org

..uk

P A G E 6

MANUFACTURER: Manufactured

in Denmark by Pharma Nord and distributed

by

Pharma Nord (UK) Ltd

Spital Hall

Mitford

Morpeth

NE16 3PN

PRESENTATION: Tablets (150 in a

box) typically containing:

selenium (organic) 75 mg

methionine 400 mg

beta-carotene 3 mg

vitamin C 150 mg

vitamin E 47 mg

LICENSED INDICATIONS: None

CURRENT STATUS:

Pharma-Nord have given Pancreato-

Biliary Consultants an undertaking

that Bio-Antox, the formulation of which

is based entirely on the work of the

Manchester group, will not be available

" over-the-counter " . The same company

markets a range of food supplements,

one of which is called Bio-Antioxidant,

but this should not be confused with

Bio-Antox. Both contain micronutrients

and vitamins but the formulations of

each markedly differ.

DOSAGE OF Bio-Antox in PANCREATITIS

The usual dose is four tablets daily,

adjusted at intervals according to the

results of blood and urine analyses. For

most patients the initial dosage is required

for ten weeks and a few will require

supplementary methionine (250

mg four times daily). Thereafter a proportion

will continue to need a similar

dose, with or without methionine, for a

further 10 weeks with a 25 per cent

reduction in dosage for the next six

months or so. During the following six

months 50per cent of the initial dose is

given, reducing to 25 per cent as a

maintenance dose indefinitely thereafter.

Ordinarily, blood antioxidant and free

radical marker profiles are checked at

ten weeks and 20 weeks, then six

months later and then annually via the

MRI PBS.

Reference:

S Uden et al. Antioxidant therapy

for recurrent pancreatitis: placebo controlled

trial. Alimentary Pharmacology

and Therapeutics 1 - 4: 357-71

QUESTIONS TO BE ANSWERED

Q: What need is met by this therapy?

A: Treatment of patients with

chronic or recurrent acute pancreatitis

Q: What happens now?

A: Patients are treated with analgesics,

or may go on to near-total pancreatectomy

resulting in malabsorption

and diabetes.

Q: Is quality improved?

A: Yes - patients on this treatment

do not have pain.

Q: What does the treatment

cost?

A: Less than 15 pounds per

month per patient.

Q: Can cost savings be made?

A: Yes - though not quantified,

the cost of treatment with antioxidants

is likely to be much less than present

treatments.

Advice to Health Authorities and

GP's Will increase quality and effectiveness.

May result in reduced costs.

Worth considering in specification.

WARNING: Do not self

dose with these

ingredients as without

proper monitoring some

of these ingredients are

POISONOUS! Contact

MARGARET O'BRIEN in

the first instance! She is

the Chairman of the

Manchester Patient

Support Group for the

Bioantox Treatment.

TRANS FATTY ACIDS -

CONTINUED

Specific TFA Free Foods:

Krusteze brand cake and

muffin mix, Certain

Pringles Potato chips,

Smart Balance spread

(new and patented for not

containing TFA's, and for

being able to help

balance fat metabolism),

Kraft or Henry's no fat

salad dressing,

These specifics were

included because in

these food categories it's

hard to find any

products that are TFA

free. If anyone finds

more please let me know

and I'll add them to the

list. If the theory holds

and the condition of the

pancreas improves, small

amounts of other natural

fats, such as

monounsaturated,

polyunsaturated, and

saturated, may be

beneficial. Some

research indicates that a

balanced fat diet is very

important to the overall

health of an individual.

A Final Thought:: Human

evolution has been taking

place for some 4 or 5

million years. During that

long span our digestive

systems slowly adapted

to the foods that were

consumed. Now we have

been introduced to

hydrogenated oils. It is

killing or making sick

those who cannot adapt

to it. Given a few

thousands years we

won't have to worry about

hydrogenated oil

because those not able to

adapt to it will be gone.

TRANS FATTY ACIDS >

First, a little about trans fat. I

would like to climb up on the

soapbox, but I'll save that for

another time. Trans Fatty

Acid's (TFA's) main use is to

extend the shelf life of a

product. Foods containing

trans fat have a much longer

shelf life because it doesn't

spoil. It's secondary

purpose is to change a

liquid oil into a solid. This is

why shortening is white and

solid, but pure corn oil is a

liquid. The following list

contains the most common

foods containing TFA's. It is

by no means complete. It

will identify some of the

obvious foods to watch out

for.

Trans Fat List:: Margarine,

vegetable shortening ,

pastries, peanut butter,

French fries (except those

made at home from fresh

potato's, fried in pure

vegetable oil), most fast

food, most cookies (Internet

cookies are OK), most

frozen dinners (low fat

included), most snack

foods, most cakes

(prepared and boxed, I

would . like to give the

Dough Boy an extra hard

poke in the belly), most

potato chips, most crackers,

most restaurant food

(because it is usually

prepared with shortening),

some candies, some ice

creams, some pizza

(depends on ingredients

used), most vending

machine foods.

TFA Free Foods: All fat free

foods, Meats, Eggs, Milk,

Fruits, Vegetables, Fish,

Most candy, Soft drinks,

Coffee, Tea, Vegetable oil,

Chocolate, Grilled foods,

Most cheeses, Yogurt, Most

breads, No fat mayonnaise,

Ketchup's, Mustard.

Bio-Antox, Continued:

THE PANCREATITIS SUPPORTERS

NETWORK MEMBERSHIP FORM (Internet

Sourced)

Name

..............................

Address

................................

..............................

..............................

Date of Birth ......... Telephone ...........

Payment Method: CHEQUE POSTAL ORDER

STANDING ORDER

(PLEASE RING)

Brief Medical History (Continue overleaf if needed)

...............................

................................

..............................

..............................

..............................

..............................

Please return the completed form to:

(NOTE: All information used in accordance with the terms of the Data

Protection Act)

Mr Duerden

Membership Secretary The PSN

24 Ada Road

Camberwell

London

SE5 7RW

Membership April - April: Individual £5.00 Family £8.00

Registered Charity Number 1027443

STANDING ORDER MANDATE

To ......................Bank

Address ....................

..........................

..........................

BANK BRANCH TITLE (NOT ADDRESS) SORTING CODE NO.

Please Pay UNITY TRUST BANK PLC BIRMINGHAM 08 - 60 - 01

BENEFICIARY NAME ACCOUNT NUMBER & TYPE

For the THE PANCREATITIS SUPPORTERS NETWORK 5 4 0 0 0 7 9 7 0 0

credit of

AMOUNT IN FIGURES AMOUNT IN WORDS

t The sum of £

DATE AND AMOUNT OF FIRST PAYMENT DUE DATE AND FREQUENCY

1ST APRIL 1ST APRIL - YEARLY

Commencing £ and thereafter every

*Now

DATE AND AMOUNT OF LAST PAYMENT

*Until UNTIL FURTHER £

NOTICE *Until you receive further notice from me/us in writing.

Quoting the PSN MEMBERSHIP FEE and debit my/our account accordingly

reference

Please cancel any previous standing order or direct debit in favour of the

beneficiary named above under this reference.

SPECIAL INSTRUCTIONS

ACCOUNT TO BE DEBITED ACCOUNT NUMBER

Signature(s) ........................ Date ...................

........................

Note: The Bank will not undertake to: (i) make any reference to Value Added Tax

or other indeterminate element.

(ii) advise payer's address to beneficiary.

(iii) advise beneficiary of inability to pay.

(iv) request beneficiary's banker to advise beneficiary or receipt.

* Delete if not applicable

t If the amounts of the periodic payments vary they should be incorporated in a

schedule overleaf.

SO154 (3/90)

________________________________________________________________________________\

__________________________________

INSTRUCTIONS FOR THE COMPLETION OF ABOVE FORM

PLEASE FILL IN: YOUR BANK'S NAME AND ADDRESS WHERE IT SAYS TO.........BANK

YOUR MEMBERSHIP FEE (EITHER £5 0R £8 IN FIGURES AND WORDS)

YOUR ACCOUNT NAME WHERE IT SAYS ACCOUNT TO BE DEBITED

YOUR ACCOUNT NUMBER WHERE IT SAYS ACCOUNT NUMBER

SIGN THE FORM WHERE IT SAYS SIGNATURE(S)

DATE THE FORM WHERE IT SAYS DATE

PLEASE RETURN THE WHOLE FORM TO:

Mr Duerden, Membership Secretary, The Pancreatitis Supporters Network, 24

Ada Road Camberwell London SE5 7RW

Note: With Standing Orders I cannot request any money from your account and you

can stop this at any time by writing to your Bank. All information

will be kept confidential and under the terms of the Data Protection Act.

Pancreatitis Booklets

Thank you for downloading this information pack. We hope you find it useful.

You may also be interested in a set of three booklets dealing with all types of

pancreatitis:

acute l

chronic l

cancer of the pancreas l

These booklets have been prepared by Salvay Healthcare and written by

Professor Neoptolemos.

If you would also like to receive these booklets, please send £2 to:

Pancreatitis Supporters Network

PO Box 8938

Birmingham

B13 9FW

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