RECOVERYMAZE OXALATES CALCIUM SUPP

[Guest guest]

Dear recoverymaze

So could you spell it out again for me. Do we want to take calcium

supplement swith high or low oxalate foods?

Thank you Rob's mom

WEBSITE LINKS CORRECTION/Re: Oxylates, Phenol,

Salicylate and Food Intolerances and SCDiet

I just corrected the website links.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed & cmd=Retrieve & dop

t=Abstract & list_uids=9092314 & query_hl=5 & itool=pubmed_docsum

factors affecting the risk for kidney stones in women

1: Ann Intern Med. 1997 Apr 1;126(7):497-504.

Comparison of dietary calcium with supplemental calcium and other

nutrients as factors affecting the risk for kidney stones in women.

Curhan GC, Willett WC, Speizer FE, Spiegelman D, Stampfer MJ.

Department of Nutrition, Harvard School of Public Health, Boston, MA

02115, USA.

BACKGROUND: Calcium intake is believed to play an important role in

the formation of kidney stones, but data on the risk factors for stone

formation in women are limited. OBJECTIVE: To examine the association

between intake of dietary and supplemental calcium and the risk for

kidney stones in women. DESIGN: Prospective cohort study with 12-year

follow-up. SETTING: Several U.S. states. PARTICIPANTS: 91,731 women

participating in the Nurses' Health Study I who were 34 to 59 years of

age in 1980 and had no history of kidney stones. MEASUREMENTS:

Self-administered food-frequency questionnaires were used to assess

diet in 1980, 1984, 1986, and 1990. The main outcome measure was

incident symptomatic kidney stones. RESULTS: During 903,849

person-years of follow-up, 864 cases of kidney stones were documented.

After adjustment for potential risk factors, intake of dietary calcium

was inversely associated with risk for kidney stones and intake of

supplemental calcium was positively associated with risk. The relative

risk for stone formation in women in the highest quintile of dietary

calcium intake compared with women in the lowest quintile was 0.65

(95% CI, 0.50 to 0.83). The relative risk in women who took

supplemental calcium compared with women who did not was 1.20 (CI,

1.02 to 1.41). In 67% of women who took supplemental calcium, the

calcium either was not consumed with a meal or was consumed with meals

whose oxalate content was probably low. Other dietary factors showed

the following relative risks among women in the highest quintile of

intake compared with those in the lowest quintile: sucrose, 1.52 (CI,

1.18 to 1.96); sodium, 1.30 (CI, 1.05 to 1.62); fluid, 0.61 (CI, 0.48

to 0.78); and potassium, 0.65 (CI, 0.51 to 0.84). CONCLUSIONS: High

intake of dietary calcium appears to decrease risk for symptomatic

kidney stones, whereas intake of supplemental calcium may increase

risk. Because dietary calcium reduces the absorption of oxalate, the

apparently different effects caused by the type of calcium may be

associated with the timing of calcium ingestion relative to the amount

of oxalate consumed. However, other factors present in dairy products

(the major source of dietary calcium) could be responsible for the

decreased risk seen with dietary calcium.

PMID: 9092314 [PubMed - indexed for MEDLINE]

[2]

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed & cmd=Retrieve & dop

t=Abstract & list_uids=9761503 & query_hl=8 & itool=pubmed_docsum

1: Nephrol Dial Transplant. 1998 Sep;13(9):2241-7

.. High-calcium intake abolishes hyperoxaluria and reduces urinary

crystallization during a 20-fold normal oxalate load in humans.

Hess B, Jost C, Zipperle L, Takkinen R, Jaeger P.

Department of Medicine, University Hospital, Berne, Switzerland.

BACKGROUND: The aim of the study was to test whether increasing

dietary calcium intake lowers intestinal oxalate absorption and

thereby prevents hyperoxaluria and urinary crystallization during a

20-fold normal oxalate load in healthy subjects. METHODS: Fourteen

healthy male volunteers (age 23-44 years, BMI 21.5-27.7 kg/m2)

collected 24-h urines while on free-choice diet as well as on two

standardized diets. The latter contained 2545 kcal, 2500 ml of mineral

water, 102 g of protein, 13.6 g of sodium chloride and 2220 mg of

oxalate (approximately 20-fold content of an average diet). Subjects

were studied twice while on the standardized diet, once while eating a

normal amount of calcium (1211 mg/day, oxalate-rich diet), and once

while eating 3858 mg of calcium/day (calcium and oxalate-rich diet).

RESULTS: Compared with the free-choice diet (322+/-36 micromol/d), UOx

x V increased to 780+/-72 micromol/d on the oxalate-rich diet

(P=0.001) and fell again to 326+/-31 micromol/d on calcium and

oxalate-rich diet (P=0.001 vs oxalate-rich diet). Urinary glycolate (a

metabolic precursor of Ox) always remained below the upper limit of

the normal range and did not change between different diets,

indicating that changes in UOX x V reflect respective variations in

intestinal absorption of Ox. Uca x V was 4.60+/-0.45 mmol/d on the

free-choice diet and 3.20+/-0.32 mmol/d on the oxalate-rich diet

(P=0.011 vs free-choice diet); it increased to 7.28+/-0.74 mmol/d on

the calcium- and oxalate-rich diet (P=0.001 vs free-choice and

oxalate-rich diets). As indicated by the AP (CaOx) index (Tiselius),

urinary supersaturation did not vary significantly between the three

diets. In freshly voided morning urines (studied in 8/14 subjects) on

the oxalate-rich diet, CaOx crystals or crystal aggregates of up to 80

microm diameter were found in 5/8 urines, whereas this never occurred

on the free-choice diet and only t once on the calcium- and

oxalate-rich diet. CONCLUSION: Increasing calcium intake while eating

Ox-rich food prevents dietary hyperoxaluria and reduces CaOx

crystallization in healthy subjects. This further illustrates that

dietary counseling to idiopathic calcium-stone formers should ensure

sufficient calcium intake, especially during oxalate-rich meals.

Publication Types:

* Clinical Trial

* Randomized Controlled Trial

PMID: 9761503 [PubMed - indexed for MEDLINE]

For information on the Specific Carbohydrate Diet, please read the book

_Breaking the Vicious Cycle_ by Elaine Gottschall and read the

following websites:

http://www.breakingtheviciouscycle.info

and

http://www.pecanbread.com