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Research Update - September/October 2008 In this issue:Herbal Extract Safe and Effective for OAA compound obtained from the herb Boswellia serrata and concentrated to improve its effectiveness has been shown in a recent placebo-controlled study to improve pain and physical ability among people with osteoarthritis, and greatly reduce levels of an enzyme known to degrade joint cartilage. Making a Better Joint ReplacementUsing an Arthritis Foundation grant, scientists at Georgia Institute of Technology have developed a special coating to cover the titanium used in artificial joints, which promotes better bonding and bone growth, allowing the joint to last longer and stay stronger. Cardiovascular Risk and NSAID UseNonsteroidal anti-inflammatory drugs (NSAIDs) are very important pain and inflammation reducers for people with arthritis, but recent concerns over their effects on the heart have made people nervous. A new study has found that although those with specific risk factors who take NSAIDs do have a higher likelihood of experiencing heart attack or stroke, the majority of the public is not at increased risk. Relationships Linked With RA HealthAccording to new Arthritis Foundation-funded research, people with rheumatoid arthritis who enjoy mutual, give-and-take conversations with their spouses have better physical and psychological health than those who have poorer relationships. Poverty and LupusPeople with lupus who struggle to make ends meet and who live in poverty-stricken neighborhoods are at great risk of developing depression. Does their physical health suffer as well? Predicting Who Will and Won’t Find ReliefBiologic agents have revolutionized the treatment of rheumatoid arthritis, but as many as 40 percent of people who take them do not receive adequate relief from the disease’s symptoms. Funded in part by an Arthritis Foundation grant, scientists have identified common clinical traits among people with RA who failed to improve and stopped taking the medication. Profile in Research: P.J. Utz, MDMeet lupus researcher and big fan of the Arthritis Foundation, Dr. J. Utz – or P.J. as he’s better known. Arthritis Foundation Research Program GoalsChief Science Officer, A. Hardin, MD, has announced the five primary goals of the organization’s research grant program. Read about them and learn how these objectives can ultimately help people with arthritis. Download this issue in PDF format*This is a PDF document and requires Adobe Acrobat Reader. Research Update is compiled by the Research Communications Specialist, National Office.To ensure delivery to your inbox, please add donor_relations@... to your address book to make certain that you receive your deliveries from the Arthritis Foundation in a timely and consistent manner. This e-mail was sent to: neurosarcoidosis You may update your email address and manage the e-newsletters you receive from the Arthritis Foundation by clicking here. We hope this email was not an inconvenience to you. To no longer receive Research Update, click here.To unsubscribe from all email communications from the Arthritis Foundation, please click here. For specific information, please contact us at donor_relations@..., 1- or Arthritis Foundation, 1330 West Peachtree Street, Suite 100, Atlanta, GA 30309. Copyright 2008 Arthritis Foundation. All rights reserved. Arthritis Foundation Privacy Policy.

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