BPD without gastric restriction (for Chris Hawkins)

[Guest guest]

Here is the abstract.

Hull

Biliopancreatic diversion preserving the stomach and pylorus in the

treatment of hypercholesterolemia and diabetes type II: results in

the first 10 cases.

Noya G, Cossu ML, Coppola M, Tonolo G, Angius MF, Fais E, Ruggiu M.

Cattedra di Chirurgia d'Urgenza e Clinica Chirurgica Generale,

Universita' di Sassari, Italy.

BACKGROUND: Besides weight loss Scopinaro's operation produces

correction of hypercholesterolemia and noninsulin dependent diabetes

mellitus in all patients who suffer from these conditions. These

results encouraged us to perform biliopancreatic diversion (BPD)

without gastric resection, thus preserving the functions of the

stomach and pylorus in moderately overweight patients with

hypercholesterolemia associated with diabetes type II and

hypertriglyceridemia. METHODS: Between March 1996 and July 1997 we

performed BPD without gastric resection on 10 moderately overweight

patients [mean body mass index (BMI) = 33.2 kg/m2]. All patients had

suffered from hypercholesterolemia and hypertriglyceridemia for more

than 5 years. Ten patients suffered from diabetes type 11; four of

them had had insulin treatment or oral anti-diabetic agents; the

other patients all had hyperglycaemia in the fasted state and

diabetes confirmed by preoperative oral glucose tolerance test

(OGTT). Five patients suffered from hypertension. RESULTS: In all

patients, cholesterol and triglyceride levels returned to normal

within the first postoperative month. Glycemia also stabilized at

normal values in nine patients within the early weeks after surgery.

One patient who took 70 U of insulin reduced his daily intake to 35 U

2 months postoperatively. In all patients blood pressure returned to

normal. Weight loss was predictably slight (10-15 kg). CONCLUSIONS:

Our experience with the procedure found that this new method seems to

be as effective in controlling lipidic metabolism and diabetes II as

the original version of BPD. As expected, weight loss is only

moderate, so that the modified BPD is not suitable for very obese

patients.

PMID: 9562490 [PubMed - indexed for MEDLINE]

>

> The BPD procedure dramatically lowers cholesterol INDEPENDENT of

> weight loss. A group of patients in Italy who were moderately

> overweight were given an BPD procedure without any gastric

> restriction. The result was only modest weight loss, but dramatic

> improvement in lipids and blood sugar levels. Also, patients who

have

> BPD or BPD/DS show dramatic drops in cholesterol and blood sugar

> levels even BEFORE significant weight loss.

> The data is clear that the malabsorptive procedures are the most

> effective and eliminating lipud disorders and diabetes.

>

> =======

> which study and where can I find it? I'd like to put this

in my

> preop notebook. Thanks

>

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> Hawkins

> netmaker2@y...

>

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>

> " Those who can't laugh at themselves leave others to do the job! "