Re: Aromatase inh vs Lupron

[Guest guest]

,

I was very interested in what you wrote here (about a month ago).

is in early puberty (age 10). Our doctor wants to start him

on Lupron. Actually, he's had one injection already, but that was

just to test his hormone response to confirm that he's in puberty

(answer: yes).

Dr. H. suggested should be on aromatase inhibitors last year,

when he was in adrenarche. But our doctor wasn't in favor of that.

I wonder what she would say now that he's in puberty (aside from

" I told you so - you should have listened to my advice last year! " ).

I wish the Magic conference was sooner! I'm anxious to get Dr. H.'s

opinion, and also hear her presentations on early puberty.

Are there any articles in the Magic libarary on this subject that you

recommend?

- Joe

>

> Gotta make dinner but I will try and write more later when I finish

> more research. But I found some fascinating stuff last night about

> GnRHA -- (Lupron) which blocks estrogen AND testosterone

> (essentially halting puberty) versus aromotase in. GnRHA are

needed

> for specific situations such as precocious puberty, when a parent

> finds their 2 year old little girl menstruating.

>

> However, Lupron has been found to result in adolescents with

reduced

> bone mineral content, reduced body muscle, and some other stuff

> (e.g., think of what testosterone does to teenage boys and then you

> are blocking it). The current investigations are looking at

whether

> or not blocking only estrogen will work just as well, for

situations

> when you are trying to slow the advancement of bone age down, and

> buy a child " extra growing time. " Some children, primarily boys in

> that the boy child wants every extra inch of height he can get, may

> end up using an A.I. and Lupron.

>

> Anyway, I have a lot more research now to do on Lupron. We

> personally have decided that we will not use Lupron on . If

> the A.I. doesn't work and she goes into full puberty, we'll wing

> it. But she is now 9 yrs old. It may have been a different

> decision had she been 7...

>

> Jenn

>

[Guest guest]

Joe,

It is my understanding that you should be using both for now

because they do different things. One supresses estrogen production

(Arimidex) while the other supresses puberty (Lupron). It is not too

late to start the Arimidex.

Is getting the Lupron shots every 28 days? They can be very

painful and it's inconvenient to have to take him every 4 weeks. Ask

your doctor about the Lupron that is used every three months. There is

also Zoladex, with which I am more familiar. That is a pellet that is

inserted just under the skin in the abdomen. Done correctly, it is

painless, or involves very little discomfort. If you wnat to know

more, email me at magicrss@ hotmail.com

Jodi Z