Re: RSS/SGA kids do often have higher cholesterol

[Guest guest]

Everyone - I am sorry to have to disagree. All of the research on

RSS and SGA children points to a risk of higher " lipid " levels,

which includes cholesterol. These higher lipid levels are found

from birth onwards -- defeating my initial thought that the levels

were higher becase we fed them such horrendous high fat foods for so

long. These children also often have higher than normal blood

pressures from birth onwards. The studies that found these (and

there are many) compared the children to same age, same sex

children. These factors combined with others are what have led

researchers to study the risk of cardiovascular issues as adults,

type 2 diabetes, insulin resistance, etc for RSS/SGA. This is what

Dr. Czernichow from Paris will be speaking on at this summer's MAGIC

convention for the RSS/SGA group.

Repeated studies, including double-blind studies with control groups

(the good ones I look for), have found that growth hormone treatment

has been found to reduce both the child's blood pressure and lipid

levels (and that these lower levels have been found to be sustained

after GH discontinuation). Again, however, GHT does increase the

fasting and glucose insulin levels above normal levels (only during

the time on GHT), and the children must be monitored carefully.

My own daughter's cholesterol, however, was a scary low 99, at her

last test. However, my husband has an extremely low cholesterol as

well, even now at age 39.

Please remember that all of these studies are available FREE to any

member of MAGIC. Katy and I have created a listing of the articles,

and on the last column, put in a summary of what is in the article,

to make it easier for families to pick and choose (as we now have

more than 100 articles). Please contact MAGIC 1-800-3MAGIC3 for

more information.

Thank you! Salem

Hokken-Koelega A, Sas T, van Pareren Y; Effects of long-term growth

hormone treatment on body composition, carbohydrate metabolism,

blood pressure and lipids in short children born small for

gestational age. Horm Research. 2003; 59(suppl. 1):138.

Short children born small for gestational age. Novo Nordisk. 2003;

p. 1-32.

Hokken-Koelega A, van Pareren Y, Sas T, Arends N: Final height

data, body composition and glucose metabolism in growth hormone

treated short children born small for gestational age. Horm

Research. 2003; 60(suppl. 3):113-114.

van Pareren Y, Mulder P, Houdijk M, Jansen M, Reeser M, Hokken-

Koelega A: Effect of discontinuation of growth hormone treatment on

risk factors for cardiovascular disease in adolescents born small

for gestational age. Jrl of Clin Endocr & Metabolism. 2003; 88

(1):347-353.

> >

> > Hello,

> > My daughter is quite a bit older than most of your children but

i'm

> > hoping that someone can help me with this. Ada recently had some

> > blood work done to see what was going on inside.

> >

> > Her cholesterol came back at 199. I'm really worried about this.

> > It's never been checked before so maybe it's 'normal for her' .

> She

> > does not eat alot of animal protein or fat so i'm quite

suprised.

> > She no longer sees a endocrinologist and her regular

pediatrician

> > doesn't know much about RSS.

> > She also had an abnormal score on the prealbumin.

> >

> > Have any of you run across this or heard one way or the other

how

> > our children's cholesterol tends to be?

> >

> > Have any of the adults with RSS had their's checked?

> >

> > thanks in advance for any insight you can give.

> > Signe