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RE: Question re shots

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I have IPF and diabetes and am participating in the Bosentan

drug trial. My pulmonologist told me to get the normal flu shot now and

the H1n1 when it is made available to seniors.

Go figure.

Jack Mc sdale

From:

Breathe-Support [mailto:Breathe-Support ] On

Behalf Of murphy.patrick10

Sent: Wednesday, November 04, 2009 4:33 PM

To: Breathe-Support

Subject: Question re shots

My trial co-ordinator called today to give me

updates on the H1N1 and flu shots today. Right up til now I was told not to get

them as they hadn't tested them against the trial drug.The results are just as

confusing as rocket science to me. They said the shots will not affect the drug

as it is not a live virus. But what they don't know is how the drug will affect

the flu shots. Or if I am getting 5mg will it affect it less than if I am on

15mg. Not to mention if it is placebo it is all for nothing. Unofficially I am

probably getting some of the drug due to my reaction after the first 2

infusions. What dose who knows. Also it is possible that the drug could

diminish the effect of the shots but they don't know to what degree. If I get a

reaction is it from the shot or the trial drug reacting to it? They just don't

know. So the question is, do I or don't I. I am leaning towards getting it as I

believe in being proactive rather than reactive and let the chips fall where

they may. I guess I am just looking for varying comments. Help!

Merf2 IPF 05

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Merf, isn't medicine crazy.. flip a coin.. Love & Prayers, Peggy Florida, IPF/UIP 2004"I believe that friends are quiet angels who lift us to our feet, when our wings have trouble remembering how to fly." My trial co-ordinator called today to give me updates on the H1N1 and flu shots today. Right up til now I was told not to get them as they hadn't tested them against the trial drug.The results are just as confusing as rocket science to me. They said the shots will not affect the drug as it is not a live virus. But what they don't know is how the drug will affect the flu shots. Or if I am getting 5mg will it affect it less than if I am on 15mg. Not to mention if it is placebo it is all for nothing. Unofficially I am probably getting some of the drug due to my reaction after the first 2 infusions. What dose who knows. Also it is possible that the drug could diminish the effect of the shots but they don't know to what degree. If I get a reaction is it from the shot or the trial drug reacting to it? They just don't know. So the question is, do I or don't I. I am leaning towards getting it as I believe in being proactive rather than reactive and let the chips fall where they may. I guess I am just looking for varying comments. Help! Merf2 IPF 05

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