Guest guest Posted September 15, 2009 Report Share Posted September 15, 2009 , Last night when I was thinking of what Bruce wrote, I wondered what might happen if Pirfendone didn't make money for Intermune. Would it discourage further research? After all, it does take lots of money and time to develop and research a new drug now, much more than in the past. Pirfendone may have a marginal benefit over all, but words that the media may use such as " breakthrough " and " miracle drug " may in the long run promote and reward mediocraty. Jerry/Mississippi/54/IPF/dx April 05 > > > > > > > > > > > > > > > > Hello Jerry, My IPF was diagnosed in 10-2008. I am 73. My > > > brother > > > > > died from IPF 7-2008 at age 70. It must be our families disease. > > > > > > > > > > > > > > > > My brother was an MD who had much faith in steroids. I saw > > > what > > > > > effect prednizone had on him. He only lasted 22 months even with a > > > lung > > > > > transplant-- the lung was no good match for him. He developed severe > > > > > osteoporosis and aged about 15 years in two years. > > > > > > > > > > > > > > > > I would like to survive as long as you have. Are you using > > > > > prednizone? > > > > > > > > If possible, how much per day and how long have you used it? > > > How > > > > > do you feel about side effects? > > > > > > > > > > > > > > > > I takes me four to six hours each day to clear my lungs. I > > > was > > > > > put on 60 mg of prednizone and I reduced it to zero. I have had a > > > very > > > > > stressful > > > > > > > > summer and so I am taking 20 mg per day. This is not enough to > > > > > clear my lungs. I am now fighting with a full load of allergies. > > > > > > > > > > > > > > > > Burns > > > > > > > > > > > > > > > > Burns > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > ____________ _________ _________ __ > > > > > > > > From: jerryb888 <jerryb888@ ..> > > > > > > > > To: Breathe-Support@ yahoogroups. com > > > > > > > > Sent: Tuesday, September 8, 2009 11:54:18 PM > > > > > > > > Subject: Beverley Joy > > > > > > > > > > > > > > > > > > > > > > > > Hello Beverley Joy, > > > > > > > > Am I right thinking you have an appointment with your new > > > > > pulmonologist tomorrow the 9th? I hope all goes well with your first > > > > > visit and that you will find a friendly, knowledgeable lung man. But > > > you > > > > > know if you aren't happy, there are other qualified doctors near > > > you. > > > > > Take care of yourself and I'll be looking to hear some news. As i'll > > > be > > > > > traveling down to tomorrow for the Celtic Fest, I may not > > > have > > > > > access to a computer link as often as here, but I'll check in when I > > > can > > > > > and see if you have posted. Take care. Oh yes, notice I typed in > > > blue > > > > > like Mamasher? Since we are going to use blue for our color, I may > > > start > > > > > emailing to everyone in blue all the time. What do you think? > > > > > > > > Jerry?Mississippi/ 54/IPF/dx April 05 > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 15, 2009 Report Share Posted September 15, 2009 Jerry Will it discourage other pharmaceuticals? No. However, with the economic changes, investors are not now as quick to pour money into companies that have never done anything to generate any sizable revenues. Seed capital is tight. This isn't just pharmaceutical. In fact, because it has hit high tech even harder, some have decided pharmaceutical might be a better investment. The economic climate that saw money poured into companies operated by questionable management with the lack of proven success was unhealthy and is largely gone. But the major pharmaceuticals are always trying new things and there will always be a place for the well capitalized and well managed new endeavor. Hitting one drug or one software success or one new product can still take one from zero to success. When I was in the business, the rule of thumb for investors on companies such as these was that on 80% of them, you would lose every penny you invested. You just hoped somewhere in the other 20% there was that one that you invested in and multiplied your money 100 times. > > > > > > > > > > > > > > > > > > Hello Jerry, My IPF was diagnosed in 10-2008. I am 73. My > > > > brother > > > > > > died from IPF 7-2008 at age 70. It must be our families disease. > > > > > > > > > > > > > > > > > > My brother was an MD who had much faith in steroids. I saw > > > > what > > > > > > effect prednizone had on him. He only lasted 22 months even with a > > > > lung > > > > > > transplant-- the lung was no good match for him. He developed severe > > > > > > osteoporosis and aged about 15 years in two years. > > > > > > > > > > > > > > > > > > I would like to survive as long as you have. Are you using > > > > > > prednizone? > > > > > > > > > If possible, how much per day and how long have you used it? > > > > How > > > > > > do you feel about side effects? > > > > > > > > > > > > > > > > > > I takes me four to six hours each day to clear my lungs. I > > > > was > > > > > > put on 60 mg of prednizone and I reduced it to zero. I have had a > > > > very > > > > > > stressful > > > > > > > > > summer and so I am taking 20 mg per day. This is not enough to > > > > > > clear my lungs. I am now fighting with a full load of allergies. > > > > > > > > > > > > > > > > > > Burns > > > > > > > > > > > > > > > > > > Burns > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > ____________ _________ _________ __ > > > > > > > > > From: jerryb888 <jerryb888@ ..> > > > > > > > > > To: Breathe-Support@ yahoogroups. com > > > > > > > > > Sent: Tuesday, September 8, 2009 11:54:18 PM > > > > > > > > > Subject: Beverley Joy > > > > > > > > > > > > > > > > > > > > > > > > > > > Hello Beverley Joy, > > > > > > > > > Am I right thinking you have an appointment with your new > > > > > > pulmonologist tomorrow the 9th? I hope all goes well with your first > > > > > > visit and that you will find a friendly, knowledgeable lung man. But > > > > you > > > > > > know if you aren't happy, there are other qualified doctors near > > > > you. > > > > > > Take care of yourself and I'll be looking to hear some news. As i'll > > > > be > > > > > > traveling down to tomorrow for the Celtic Fest, I may not > > > > have > > > > > > access to a computer link as often as here, but I'll check in when I > > > > can > > > > > > and see if you have posted. Take care. Oh yes, notice I typed in > > > > blue > > > > > > like Mamasher? Since we are going to use blue for our color, I may > > > > start > > > > > > emailing to everyone in blue all the time. What do you think? > > > > > > > > > Jerry?Mississippi/ 54/IPF/dx April 05 > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
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