Re: Jenn - Arimidex & adrenarche

[Guest guest]

Kim, very interesting, and just one more piece of data. The studies

on the use of aromitase inhibitors to halt the rapid bone age

advancement are NOT conclusive at this time -- the studies haven't

been around long enough. Stanhope basically told me that we had

nothing to lose, to try it because of the drug's safety record. But

he also said he wasn't 100% sold on whether or not it would halt the

rapid progression of the bone age. He wonders if there is something

else going on in the RSS/SGA kid besides just the estrogen part

(with regards to the bone age advancing).

These next couple of conventions, I think, are going to be critical

for us parents of pre-adolescents, as so many studies are currently

ongoing... I can't wait to hear what Dr. H says about . We

should all compare notes after our visits!!! JEnn

> Hi ,

>

> I was shocked to read in your post that Arimidex doesn't stop

> adrenarche. has been on Aromasin (according to Dr. H this

is

> stronger than Arimidex) for almost 1.5 years now, though he has

been in

> adrenarche since age 3.5 years old. He continues to have the body

> odor, pimples, etc., & I have always wondered if the Aromasin is

> working. He has also been on Lupron for 2.5 years. His bone age

> continues to advance with poor growth despite maximal doses of GH

and

> labwork that is indicative that he is still in puberty. I have

lots of

> concerns for him, and am anxious to see Dr. H at the convention.

>

> Kim C.

>

>

>

> I have learned from Dr. H that the Arimidex that she is on won't

> STOP adrenarche, so the body odor and pimples keep going. It just

> specifically halts the conversion of the adrogens into estrogen,

and

> hopefully will then halt her rapid progression of her bone age.

[Guest guest]

I know this has been discussed a thousand times - what is the

difference between aromitase inhibitors and lupron - or is there.

Thanks