Guest guest Posted March 2, 2005 Report Share Posted March 2, 2005 Gotta make dinner but I will try and write more later when I finish more research. But I found some fascinating stuff last night about GnRHA -- (Lupron) which blocks estrogen AND testosterone (essentially halting puberty) versus aromotase in. GnRHA are needed for specific situations such as precocious puberty, when a parent finds their 2 year old little girl menstruating. However, Lupron has been found to result in adolescents with reduced bone mineral content, reduced body muscle, and some other stuff (e.g., think of what testosterone does to teenage boys and then you are blocking it). The current investigations are looking at whether or not blocking only estrogen will work just as well, for situations when you are trying to slow the advancement of bone age down, and buy a child " extra growing time. " Some children, primarily boys in that the boy child wants every extra inch of height he can get, may end up using an A.I. and Lupron. Anyway, I have a lot more research now to do on Lupron. We personally have decided that we will not use Lupron on . If the A.I. doesn't work and she goes into full puberty, we'll wing it. But she is now 9 yrs old. It may have been a different decision had she been 7... Jenn > > > > Although I have to agree with Jody Gough, in that I do think that > > many of Beth's postings are a bit too scientific and lack any true > > statistical studies using control groups against pediatric groups, > > and especially pediatric groups that include either RSS or SGA > > > > > > > > > http://bmj.bmjjournals.com/cgi/content/full/324/7331/238 > > (review > > > > references at bottom) > > > > > > > > Beth Quote Link to comment Share on other sites More sharing options...
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