Guest guest Posted October 1, 2003 Report Share Posted October 1, 2003 My son (2.5yr old) was also diagnosed with UC about a year ago after he has a lot of vomiting and some blood in his stool. They did a colonoscopy and said it was UC. I didn't believe it. He was put on sulfasalazine and we didn't see any more blood. I NEVER believed he had UC--he had no other symptoms. When we moved to Kansas, we saw a new GI dr and he also agreed with me. The GI doc and I believed that the enzymes were just irritating his colon. We stopped the medication and haven't had any problems with it since. On a side note, I would be very cautious about using Barium. It is counterindicative in kids with CF. It caused a severe blockage in my son--so bad it nearly required surgery. They can use something called Gastro Graffin that works fine. Jennfer > My six year old girl with CF was born with meconium illeus. She has been in the hospital with sever abdominal pain. To make a long story short, she was passing small amounts of blood in her stools, X-ray's showed a large amount of gas build up in the large intestine and stool in the small intestine. they performed a barium enema and that cleaned her out. she felt better after that but after she ate she started hurting again. She had loose stools but not runny stools. The x-ray's showed no blockages or adhesions from earlier surgery. after a week in the hospital she has been sent home. They are now telling me she could have Ulcerative colitis but does not want to do a colonoscopy until she is feeling better and not hurting. My Question is, How is this related to CF? has anyone out there had this and what is your experience with this? > Tracey Oldham > toldham@l... > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 2, 2003 Report Share Posted October 2, 2003 Hi Tracey, I am not aware of a connection between CF and ulcerative colitis. But there is a similar complication called fibrosing colonopathy, that is found more often in pwcf. When you google for CF and fibrosing colonopathy you'll get some hits. Ask your docs whether they know about this. The other real risk is, that due to the prolonged use of antibiotics pwcf are prone to infections with clostridium difficile, a nasty bug that can cause colitis too. Peace Torsten Fibrosing colonopathy revealing cystic fibrosis in a neonate before any pancreatic enzyme supplementation. Serban DE, cu P, Miu N. Pediatric Clinic II, University of Medicine and pharmacy, Cluj- Napoca, Romania. danielaserban@... Although its pathogenesis remains still unknown, fibrosing colonopathy (FCP) is considered to be the result of prolonged treatment by high doses of pancreatic enzyme preparations, in a small proportion of patients who present with cystic fibrosis (CF). We present the case of a newborn with meconium ileus (treated by conservative measures), in which, at the age of 3 weeks, the features of intestinal obstruction made necessary the removal of 15 cm of the proximal large intestine. Macroscopical and especially microscopical appearances typical for FCP were found, despite the absence of any enzymatic treatment. These findings raised the suspicion of CF, which was confirmed 4 weeks later at necropsy by the presence of characteristic pancreatic lesions. This case and another similar report in the literature suggest that the mechanism of FCP must be linked with the disease itself, at least in some patients. Thus, for us, FCP is not a " closed subject " and we sustain the importance of continuing studies, which will shed light on its etiopathogenesis. **************************************************************** Can J Gastroenterol. 2001 Sep;15(9):586-90. Colonic disorders in adult cystic fibrosis. Chaun H. St 's Hospital and University of British Columbia, 805 West Broadway, Vancouver, British Columbia V5Z 1K1, Canada. hchaun@... By 1996, the median survival of patients with cystic fibrosis (CF) in North America had increased to 31 years. With the markedly improved life expectancy, many CF patients are now adults. There is an associated increased risk of certain colonic disorders, and the emergence of other previously unrecognized disorders, in adult CF patients. The distal intestinal obstruction syndrome (DIOS), which is more common in older patients, is a frequent cause of abdominal pain. Intussusception may complicate DIOS; other differential diagnoses include appendiceal disease, volvolus, Crohn's disease, fibrosing colonopathy and colonic carcinoma. The diagnosis of acute appendicitis, although uncommon in patients with CF, is often delayed, and appendiceal abscess is a frequent complication. The prevalence of Crohn's disease in CF has been shown to be 17 times that of the general population. Right-sided microscopic colitis is a recently recognized entity in CF of uncertain clinical significance. Fibrosing colonopathy has been confined mostly to children with CF, attributed to the use of high strength pancreatic enzyme supplements, but it has been reported in three adults. Nine cases of carcinoma of the large intestine have been reported worldwide, associated with an apparent excess risk of digestive tract cancers in CF. Despite high carrier rates of Clostridium difficile in patients with CF, pseudomembranous colitis is distinctly rare, but severe cases complicated by toxic megacolon have been reported. In these patients, watery diarrhea is often absent. Adult CF patients with refractory or unexplained intestinal symptoms merit thorough investigations. Publication Types: Review Review, Tutorial Quote Link to comment Share on other sites More sharing options...
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