Guest guest Posted May 6, 2004 Report Share Posted May 6, 2004 Hi Cyndi, I don't have much to say other than I am experiencing something very similar to you with my kadian. The first week I was taking it, I had great pain relief, I was able to get it down to 1s and even 0s. I was aware when it kicked in and wore off. I still had to take the occasional oxycodone for the breakthrough pain, but was able to either take less or get the pain levels down to zero when I did. But after that first week, I noticed that the kadian just didn't seem to be working as well or even at all. I was back up to consistent pain levels of 5 to 6 with only relief to 4 and 3 with both the morphine and the oxy. I am going to see the pain doc and the PCP next week to see what they will advise about this. I am thinking that since I am still on trial to find the right dose and medication that they will be willing to either change the type of medication or increase the dosage. My understanding is that it takes a lot of trial and error to get the right combination of dose and type of medication and that only time will tell what that will be. I also suspect that a persons pain cycle / variabilty will also confound these efforts. Laurie It will be interesting if there is any explanation for why the meds worked so well for only a week. I am not sure if it was just a placebo effect or if my pain levels changed due to a change in the disease. If I get any insight into this phenomenon, I will share it with you. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 7, 2004 Report Share Posted May 7, 2004 After reading your post I realized you are experiencing what in medicine is termed tolerance. It is not unusual for a person to develope a tolerance to pain medication when taken over a prolonged period of time. I do not remember if you posted anything regarding break through pain medication. Many physicians will prescribe something like Duragesic or Oxycontin ( something that is extended release) and then something in addition for what is called break through pain that is not covered by the extended release medication, there are many drugs that can be utilized in that category such as oxy IR, actiq, liquid morphine, diluadid, it is wise to stay away from the drug combinations that contain tylenol such as percocet, tylenol and codiene combinations, lortab, vicodin, darvocet. It is very helpful if you find a physician that can be creative and educated in pain medication. Atwell LPN Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 10, 2004 Report Share Posted May 10, 2004 Cyndi, I take Methadone and Oxycodone for breakthrough pain, not duregisic patches. Those (the 25's) are actually stronger than what I am taking now. The methadone, while longer lasting than the oxycodone, still requires me to take it three times a day. I'm taking 20 mgs in the am, 15mgs at noon, and 20mgs at bedtime. My doctor has been raising mine at about a 5mg dose each time he raises it. . My oxycodone is my breakthrough and I'm allowed to take 5mg (up to to at a time and a maximum of 6 a day) if my pain is more than my pain meds will take care of. I call the doctor if the pain is worse than my normal dosages will handle. When we up the dosage, I'm supposed to take it for about 2 weeks, than my doctor ups the dosage again. Luckily, he's only had to do that once. Hope this is of some help for you. Kimber -- Kimber Vallejo, CA hominid2@... Note: All advice given is personal opinion, not equal to that of a licensed physician or health care professional. Quote Link to comment Share on other sites More sharing options...
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