Guest guest Posted April 26, 2004 Report Share Posted April 26, 2004 , You wrote, “Does anyone know what could be causing her to have nausea this bad?†The nausea that comes from Chronic Pancreatitis can just be horrific. Actually, I think it is worse than any of my pain has been, but that is just my opinion. There are many things that can be causing the nausea. The disease process in itself can cause nausea. When food is eaten and goes from the mouth to the stomach, it normally is met with digestive enzymes that are mixed in stomach fluids. Actually, saliva contains Amylase and begins the digestive process. Many people with Chronic Pancreatitis have dry mouth (for many different reasons). This is going to cause our food to hit our stomachs behind in digestion to start with. Because we produce few to no enzymes from our pancreas, or lack thereof), we either take Creon or Viokase. These compounded medications can cause nausea, even though they should be helping digest the food. Hopefully, switching to one or the other may help. Some people can tolerate Creon and/or not Viokase. Others take OTC enzymes found at health food stores. As the disease progresses, the islet cells in the pancreas become damaged and less insulin is produced. One of the side effects of what is Pancreatitis Induced Diabetes is that a condition called Gastroparesis can develop. This is when the nerves in the stomach (Gastro) become damaged, sometimes paralyzed (paresis) from the excess glucose. When this happens, the nerves don’t stimulate the muscles to move the food out of the stomach and into the duodenum, or first part of the intestine. When the food lingers in the stomach, the food begins to break down on its on, similar to a compost. That produces a byproduct of acid, hence the term, acid indigestion, and why most of us, like Jackie, take an ‘ant-acid’. You also mentioned that Jackie is taking other medications like Zocor. Many medications have bad side effects like nausea. These are usually worse when taken on an empty stomach, although some medications are supposed to be taken that way. It’s important to note that side effects and allergic or adverse reactions are two different things. Some of the known digestive side effects of Zocor are: nausea, vomiting, gas, heartburn, stomach pain/cramps, anorexia, loss of appetite, inflammation of the pancreas, Pancreatitis, hepatitis, jaundice, and fatty changes in the liver. When evaluating the side effects of a medication it is important to always have an idea of the relationship to when the medication was started and when the side effects started. There is no set rule. Some side effects can start shortly after starting a medication, and some side effects are accumulative and don not show up until after the medication has been taken for a while. Regarding treating the nausea: Talk to your healthcare provider. Make them aware of any medication that is documented as causing nausea, but particularly Pancreatitis. (I think they all list nausea). If you have medication insurance, I suggest Zofran Elixir to treat the nausea, as Phenergan causes drowsiness. The other thing that many people have to do is eat smaller more frequent meals. Karyn -- Karyn E. , RN Executive Director, PAI http://www.pancassociation.org Pancreatitis Association International Quote Link to comment Share on other sites More sharing options...
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