Guest guest Posted May 8, 2002 Report Share Posted May 8, 2002 May 8, 2002 First Aid Doctors' Views Library Health Facts Library Medical Links About Us Meet the Doctors Help Search Advanced Search Ask The Experts! Question Regarding:Relapsing Polychondritis ------------------------------------------------------------------------------ -- Viewers Question I was diagnosed with RP 12/96 with involvement of auricle of left ear.Its now moved to the right also.Increasing doses of Mtx and yo-yoing of prednisone isnt controlling my progression. How quickly does this disease progress to the trachea? What is the life expectancy then? What are the percentages of it staying only in the ears? Nobody including doctors can give me a feel of what to expect. I like to be somewhat prepared. I relate to facts not guess work. Other than this disease Im generally healthy. Thank You. ------------------------------------------------------------------------------ -- Doctors Answer Relapsing polychondritis is a disease of inflammation of cartilage and related tissues. While the cause is not known, it is felt to be a result of an abnormal immune system that spontaneously becomes overly active to promote inflammation in the tissues involved. Relapsing polychondritis is not common and is not predictable. Common areas of cartilage inflammation in relapsing polychondritis include the ears and nose. Active inflammation is characterized by redness, pain, swelling, and tenderness of the tissues. Other areas of inflammation include the joints, eyes, cartilage areas of the breathing passages and chest wall, and the aorta. Indeed, some patients with relapsing polychondritis never have ear involvement (though this is not usual). Relapsing polychondritis does not necessarily progress to involve additional areas of cartilage. The symptoms of relapsing polychondritis wax and wane (hence, the term " relapsing " ). Recurrent inflammation can lead to destruction of the cartilage, causing deformity of the ears (floppy ears) and nose (saddle nose). Aorta and breathing passage disease (trachea and bronchi) can be serious. Even when there is trachea involvement, frequently patients can be monitored and treated before any risk to life expectancy occurs. Signs of early tracheal involvement include soreness in the neck, cough, and coarse breathing sounds. The diagnosis of relapsing polychondritis is suggested by signs of inflammation in the typical areas mentioned above and is supported by blood tests that indicate inflammation, such as a sedimentation rate. A biopsy of involved cartilage can ultimately confirm the diagnosis, but is not always necessary. The treatment of relapsing polychondritis is directed toward decreasing inflammation and relieving pain. Nonsteroid antiinflammatory drugs (NSAIDs) are used for mild to moderate symptoms. Prednisone is used for more significant illness. Very severe disease can require immune suppression drugs, such as cyclophosphamide. Thank you for your question. Please remember, information can be subject to interpretation and can become obsolete. Therefore, information should never be a substitute for an open and trusting doctor-patient relationship. Always consult your doctor. Quote Link to comment Share on other sites More sharing options...
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