Lenora - Re: FW: CF NEWS FROM AROUND THE WORLD

[Guest guest]

Those " X " or " stop " mutations allow some cftr into the

cells, whereas non-stop mutations do not. I have one

of these and a fragment of another and one deltaf508.

Cheers!

n

Rojas5915@...

Re: FW: CF NEWS FROM AROUND THE WORLD

>

>

> Hi everyone, I am trying to find out the exact gene that the

> Ashkenazi Jews carry for CF. Does anyone know?

> Thank you,

> Lenora

>

>

>

[Guest guest]

Zach has K710X. His doctor thinks that gentamycin will be altered,

so that it can cause the CFTR to function, but will not have

antibiotic properties, if this is possible. I asked him if this

could work for Zach, then he would be on antibiotic his whole life.

His theory is that repeated use of antibiotics can cause the bugs to

become resistant to the antibiotic, but if the antibiotic corrects

the CFTR function then there may not be a need to worry about

antibiotic resistance.

So much to think about.

Sara - mommy of Zach 20 months wcf

> Thanks Keeley. My son has one (G542x). I wish the CFF sounded more

> hopeful about this. Also, I wonder about all the known side

effects

> from Gentamycin.

>

> >Lenora,

> >

> > The article refers to stop mutations, which are a specific

class

> >of mutations. I think all the stop mutations end in " X " . My

> >daughter has one, R553X. I know there are several more stop

> >mutations. Hope that helps.

> >

> >Keeley

> >Mom to Leila, 15m. wcf and zz alpha, and Hadley, 3.5 yrs. nocf

> >

> > Re: FW: CF NEWS FROM AROUND THE WORLD

> >

> >

> > Hi everyone, I am trying to find out the exact gene that the

> > Ashkenazi Jews carry for CF. Does anyone know?

> > Thank you,

> > Lenora

> >

> >

> >

[Guest guest]

I cannot find the same detail anywhere that I once was

able to, but as I recall R553X was of ish origin.

We have to consider my age here, gang!

Love to all at cfparents, and to Lenora,

n

Rojas5915@...

Re: FW: CF NEWS FROM AROUND THE WORLD

> >

> >

> > Hi everyone, I am trying to find out the exact gene that the

> > Ashkenazi Jews carry for CF. Does anyone know?

> > Thank you,

> > Lenora

> >

> >

> >

[Guest guest]

Sara, what you posted about gentamycin is just what my

doctor told me as well--glad to know that he is on target!

Love to you and to yours and all at cfparents,

n

Rojas5915@...

Re: FW: CF NEWS FROM AROUND THE WORLD

> > >

> > >

> > > Hi everyone, I am trying to find out the exact gene that the

> > > Ashkenazi Jews carry for CF. Does anyone know?

> > > Thank you,

> > > Lenora

> > >

> > >

> > >

[Guest guest]

Great thinking. .I wish, hope it can be worked out by those great

researchers. I was concerned about posted that, but was so intrigued

with it I just took a chance . I do hope no one minded. I get the BOOMER

news letter daily I figured lots of folks got it . Its free & so easy

to get . Sign up on their web site www.esiason.org

LOVE & HUGS< GRANDMOMBEV

Lenora - Re: FW: CF NEWS FROM AROUND THE WORLD

Zach has K710X. His doctor thinks that gentamycin will be altered,

so that it can cause the CFTR to function, but will not have

antibiotic properties, if this is possible. I asked him if this

could work for Zach, then he would be on antibiotic his whole life.

His theory is that repeated use of antibiotics can cause the bugs to

become resistant to the antibiotic, but if the antibiotic corrects

the CFTR function then there may not be a need to worry about

antibiotic resistance.

So much to think about.

Sara - mommy of Zach 20 months wcf

> Thanks Keeley. My son has one (G542x). I wish the CFF sounded more

> hopeful about this. Also, I wonder about all the known side

effects

> from Gentamycin.

>

> >Lenora,

> >

> > The article refers to stop mutations, which are a specific

class

> >of mutations. I think all the stop mutations end in " X " . My

> >daughter has one, R553X. I know there are several more stop

> >mutations. Hope that helps.

> >

> >Keeley

> >Mom to Leila, 15m. wcf and zz alpha, and Hadley, 3.5 yrs. nocf

> >

> > Re: FW: CF NEWS FROM AROUND THE WORLD

> >

> >

> > Hi everyone, I am trying to find out the exact gene that the

> > Ashkenazi Jews carry for CF. Does anyone know?

> > Thank you,

> > Lenora

> >

> >

> >

[Guest guest]

I guess that I sort of forgot to mention that there had been

some suggestion on many lists that gentamicin (reconfigured) might be

especially effective in stop

mutations, and someone somewhere wrote in asking

what mutations Ashkenazi Jews carried! I cracked up on

several lists as there are hundreds. I am a Sephardic Jew

but nonetheless we do have a fairly high degree of stop

mutations, possibly explaining some degree of longevity--

though my generation and my cousins are over-extending

ourselves. And my adult " kid " wcf is half Ashkenazi and

half Sephardic and is a double deltaf508 and is doing very

well at the tender age of 38--I think! I can barely get my

own age straight, much less my children's and mutations;

they are all carriers of deltaf508--those who do NOT

have cystic fibrosis. We are all kind of like one giant cf

" camp " or retreat or something like that!

Love to all at cfparents,

n

Rojas5915@...

Re: FW: CF NEWS FROM AROUND THE WORLD

> >

> >

> > Hi everyone, I am trying to find out the exact gene that the

> > Ashkenazi Jews carry for CF. Does anyone know?

> > Thank you,

> > Lenora

> >

> >

> >