Guest guest Posted August 7, 2010 Report Share Posted August 7, 2010 Alyssa I have had elevated liver enzymes several times since developing Sphincter of Oddi dysfunction (affects biliary tree functioning). The highest levels existed the first time, and my gastroenterologist discovered a blockage in my common bile duct that didn’t show up on any of the usual upper GI scans. He found it because he was doing an ERCP. Whenever I experience severe biliary tree symptoms my doctor has my liver enzymes checked twice over a 6-week period, in case I’ll need another ERCP; since the first time, my liver enzymes lowered without any intervention. My liver and pancreas enzymes and functions are tested thoroughly twice a year because of the Sphincter of Oddi malfunctioning, so I keep track of my levels. Probably not something you’re dealing with! My immune system rejects every digestive enzyme I’ve tried, so I’m not taking any. And I’m not on the medications you are. So not much help to you, I realize. Elevated liver enzymes can show up occasionally and then disappear, with no specific cause discovered. You might be dealing with a temporary biliary tree slow-down, perhaps gallstones, causing the enzymes to rise. I’d suspect the digestive enzymes before your medications, however, as that could be a contributing cause – the dosage you’re using might just be too high for your liver to process. Kim M. SCD 6 years Sphincter of Oddi dysfunction 6+ years neurological & spinal deterioration 3+ years >>>>>>>>>>>>>>>>>>>>>>>. Since I'm getting a colonoscopy on Tuesday and Duke is really bad about keeping track of all my bloodwork, I just went in today to get some STAT labs done. Well, apparently my liver enzymes are over 500, and the normal range is 0-40. It said 'alert' on the printout. Anyways, I'm guessing it's the azatioprine, but I've also been taking a lot of digestive enzymes recently. Has anyone had any liver enzyme elevations related to digestive enzymes? Or azathioprine? I'd like to know for sure which it is... Thanks! Cheers! Alyssa 16 yo UC April 2008, dx Sept 2008 SCD June 2009 (restarted) Azathioprine 75 mg 1x per day Prednisone 12.5 mg 1x per day (trying to wean!!!!) Quote Link to comment Share on other sites More sharing options...
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