Re: OT-LDN youtube video explaining How LDN Works

[Guest guest]

Hi Group,

I've been on LDN Since June 1, 2009, when I began participating in the Low Dose

Naltrexone for Fibromyalgia Clinical Trial at Stanford. I started out at 4.5 mg

but then dropped down a couple months ago to 3.0 mg which seems to be working

better for me. Recently I found this video on youtube which I think explains

pretty well how LDN works. Hope you all enjoy! :-)

http://www.youtube.com/watch?v=xr-n8jMLenU

Please let me know if the link doesn't work.

Thanks!

Tamra in Gilroy

SCD Day 102

[Guest guest]

Thanks for the link.  I didn't hear any reference to it being an immunosuppressant though.  There's lots of SCD and LDN videos, I always forget to check youtube.

 

Debbie 41 cd

 

Hi Group,I've been on LDN Since June 1, 2009, when I began participating in the Low Dose Naltrexone for Fibromyalgia Clinical Trial at Stanford. I started out at 4.5 mg but then dropped down a couple months ago to 3.0 mg which seems to be working better for me. Recently I found this video on youtube which I think explains pretty well how LDN works. Hope you all enjoy! :-)

http://www.youtube.com/watch?v=xr-n8jMLenUPlease let me know if the link doesn't work.Thanks!Tamra in GilroySCD Day 102

[Guest guest]

I believe this is relatively new language that Dr. Zagon is using for public consumption.They are also just starting to figure this stuff out now - what it does, how it works. MaraThanks for the link. I didn't hear any reference to it being an immunosuppressant though. There's lots of SCD and LDN videos, I always forget to check youtube. Debbie 41 cd Hi Group,I've been on LDN Since June 1, 2009, when I began participating in the Low Dose Naltrexone for Fibromyalgia Clinical Trial at Stanford. I started out at 4.5 mg but then dropped down a couple months ago to 3.0 mg which seems to be working better for me. Recently I found this video on youtube which I think explains pretty well how LDN works. Hope you all enjoy! :-)http://www.youtube.com/watch?v=xr-n8jMLenUPlease let me know if the link doesn't work.Thanks!Tamra in GilroySCD Day 102

[Guest guest]

This video still looks like an immune modulator. The immune system is

temporarily affected by the low dose LDN but the rebound affect is for better

control of the system so it responds correctly. I would not think of this like

an immune suppressor like the others.

PJ

> >

> > Hi Group,

> >

> > I've been on LDN Since June 1, 2009, when I began participating in the Low

Dose Naltrexone for Fibromyalgia Clinical Trial at Stanford. I started out at

4.5 mg but then dropped down a couple months ago to 3.0 mg which seems to be

working better for me. Recently I found this video on youtube which I think

explains pretty well how LDN works. Hope you all enjoy! :-)

> >

> > http://www.youtube.com/watch?v=xr-n8jMLenU

> >

> > Please let me know if the link doesn't work.

> >

> > Thanks!

> >

> > Tamra in Gilroy

> > SCD Day 102

> >

> >

> >

> >

> >

> >

>

[Guest guest]

I imagine we'll understand it better once his paper comes out - here's hoping

he doesn't use the extremely opaque scientific prose throughout the entire

thing, so that it is actually understandable.

BTW, I wasn't referring to the video. I was referring to my citation from

earlier.

Mara

> This video still looks like an immune modulator. The immune system is

temporarily affected by the low dose LDN but the rebound affect is for better

control of the system so it responds correctly. I would not think of this like

an immune suppressor like the others.

>

> PJ

>

>

>>

>> I believe this is relatively new language that Dr. Zagon is using for public

consumption.

>>

>> They are also just starting to figure this stuff out now - what it does, how

it works.

>>

>> Mara

[Guest guest]

Yes, I see that. He did say immunosuppressant, but it does not seem to have the

side effects of the mainstream immunosuppressants used to treat IBD, so I would

think it was still different. I guess we still have a lot to learn.

PJ

> >>

> >> I believe this is relatively new language that Dr. Zagon is using for

public consumption.

> >>

> >> They are also just starting to figure this stuff out now - what it does,

how it works.

> >>

> >> Mara

>

[Guest guest]

The notion of LDN being an immunosupressant refers to the fact that by blocking the opoid receptors the immune system is supressed for a brief period of time.  The body's attempts to compensate for LDN's blocking normal functions could be said to be immunomodulatory or stimulant but naltrexone itself is, technically speaking, an immunosupressant.

fi

 

Yes, I see that. He did say immunosuppressant, but it does not seem to have the side effects of the mainstream immunosuppressants used to treat IBD, so I would think it was still different. I guess we still have a lot to learn.

PJ

[Guest guest]

I posted the link just before reading Jayne Crocker's letter from Dr. Ian Zagon

on another list saying that LDN is an immune suppressant. So I'm totally baffled

(???). All I can say is that it seems to have helped me a lot. :-)

Tamra in Gilroy

>

> This video still looks like an immune modulator. The immune system is

temporarily affected by the low dose LDN but the rebound affect is for better

control of the system so it responds correctly. I would not think of this like

an immune suppressor like the others.

>

> PJ

>

[Guest guest]

Dr. Zagon is occasionally in his own head space about LDN - the others

formulate things differently, analytically speaking. But it will be interesting

to see the finished paper he referenced to understand his scientific analysis.

Can you repost that letter from Dr. Zagon - I'm not sure whether I've seen that

or not - not sure what list it was on - there are so many these days.

Mara

> I posted the link just before reading Jayne Crocker's letter from Dr. Ian

Zagon on another list saying that LDN is an immune suppressant. So I'm totally

baffled (???). All I can say is that it seems to have helped me a lot. :-)

>

> Tamra in Gilroy

>

>

>

>

>>

>> This video still looks like an immune modulator. The immune system is

temporarily affected by the low dose LDN but the rebound affect is for better

control of the system so it responds correctly. I would not think of this like

an immune suppressor like the others.

>>

>> PJ

>>

>

>

>

>

> ------------------------------------

>

>

[Guest guest]

I sent the link and the comment about and the question about it being an immunosuppressant.  They did change the name of the low dose LDN to any dose ldn group due to some other issues.  I'm not sure how it works either--It does something, I just don't know what.  I watched the video and instead of the usual side effects of vivid, crazy nightmares--I stopped having them.  I did have anxiety last night and couldn't sleep (as opposed to sleeping finally) but I took the dose mid-day instead of at night.

 

I did feel awful the first month or more.  I think it took a long time to acclamate.

 

Just zoning out loud on this and the discussions on dosing twice per day.  I noticed doing 3mg at once did not sit well.  Doing 1.5mg twice a day gave me energy and I didn't hit that 'just soooo exhausted, I wanted to lay down for just a minute--which turns into a lot longer'.  Sorry to go on about it.  I still have nausea, still can't eat anything I want for sure.  But I just wish someone would explain it thoroughly because it's really bad when I don't take it.  Maybe that's how I used to feel or maybe it's a lot worse?  That's undecided.

 

Debbie 41 cd

[Guest guest]

For myself, I don't believe it. We'll have to see what the papera shows,

of course. I think that if LDN is immunosuppressive, it's only

during the short period when it is suppressing the endorphins, after

which (this is the way LDN works) it stimulates the body t produce

more. My experience is that within a few days of starting LDN, my

immune system starting being better able to knock out colds and things

before they got me (which had been an unrelenting, near-constant battle

for years).

I posted the link just before reading Jayne Crocker's letter from Dr.

Ian Zagon on another list saying that LDN is an immune suppressant. So

I'm totally baffled (???). All I can say is that it seems to have helped

me a lot. :-)

Tamra in Gilroy

[Guest guest]

At 01:40 PM 6/18/2010, you wrote:

I posted the link just before

reading Jayne Crocker's letter from Dr. Ian Zagon on another list saying

that LDN is an immune suppressant. So I'm totally baffled (???). All I

can say is that it seems to have helped me a lot.

:-)

LDN suppresses while it's active. In essence, it blocks the opiate /

endorphin receptors, causing the body to say, " Ack! I'm not getting

any endorphins! I need to make more! " So then, when the naltrexone

wears off, there are plenty of endorphins to go around. LOW DOSE

naltrexone only blocks the receptors for a few hours. By taking it at bed

time, we create the block just before the body would ordinarily be

pumping out a big supply of endorphins, so we get extras which are good

for inflammation, and for helping with healing.

—

Marilyn

New

Orleans, Louisiana, USA

Undiagnosed IBS since 1976, SCD since 2001

Darn Good SCD Cook

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