Guest guest Posted August 21, 2003 Report Share Posted August 21, 2003 In a message dated 8/21/2003 7:27:05 AM Eastern Daylight Time, Graduate-OSSG writes: > ? I think there is > sufficient evidence that Vioxx has caused ulcers, but what about > Bextra? Bextra is an NSAID, specifically, a COX-2 inhibitor. This is the identical classification of Vioxx. If you check the patient information sheet that comes with Bextra, or the PDR (Physicians Desk Reference), or the MPR (Monthly Prescribing Reference) under " Adverse Reactions " , it reads: " GI effects (upset, pain, ulcer, bleed), edema, hypertension, rash, etc. " That means those side effects have already been clinically seen with use of this medication. Sandy Boca Raton, FL postop ~ 03/27/02 265/128 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 7, 2004 Report Share Posted January 7, 2004 1. you (and I) don't have a normal stomach 2. I personally wouldn't take it unless absolutely necessary and then would expect to be checked for ulcers every so often (since you can get ulcers that bleed without pain). JMHO. Pam in Niceville ----- Bextra > Hello group > > I need some of your valuable experience. I had a rny w/fobi in Nov > 2002. I also have degenerative joint disease. My primary physician > has prescribed bextra for me, telling me that this is not suppose to > cause ulcers in a normal stomach and that it is the mildest of all > the nsaids. Can you guys tell me any information on this drug and > how it affects our pouch before I start taking them? Thanks for > your valuable support. I read post daily and consider your opinions > and experience very valuable in my own weight loss journey. > > > 313/156/??? > Dr. Gorospe/ Tulsa > Open rny W Fobi > > Homepage: http://groups.yahoo.com/group/Graduate-OSSG > > Unsubscribe: mailto:Graduate-OSSG-unsubscribe > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 7, 2004 Report Share Posted January 7, 2004 , Is this something you will be taking long term? My dh has a pharmacy background and what he told me is Bextra is a member of the relatively new class of painkillers called COX-2 inhibitors. It is prescribed for the relief of osteoarthritis, rheumatoid arthritis,ect. COX-2 inhibitors are part of a larger group of medications called nonsteroidal anti-inflammatory drugs (NSAIDs). All the drugs in this category (including such familiar remedies as aspirin, Motrin, and Naprosyn) relieve pain and inflammation by limiting the effect of a natural enzyme called COX-2. Unlike the older NSAIDs, however, the new COX-2 inhibitors do not interfere with COX-1, a related enzyme that exerts a protective effect on the lining of the stomach. As a result, Bextra and other COX-2 inhibitors are less likely to cause the bleeding and ulcers that sometimes accompany sustained use of the older NSAIDs. Although the chances of stomach or intestinal bleeding are low, a slight danger remains. If you are only taking this for a short time it's probably safe. Your best bet would be to talk to your surgeon and see what he thinks. > Hello group > My primary physician > has prescribed bextra for me, telling me that this is not suppose to > cause ulcers in a normal stomach and that it is the mildest of all > the nsaids. Can you guys tell me any information on this drug and > how it affects our pouch before I start taking them? Thanks for > your valuable support. I read post daily and consider your opinions > and experience very valuable in my own weight loss journey. > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 7, 2004 Report Share Posted January 7, 2004 You're right, Fay. We have to weigh these things - quality of life vs. the RISK of ulcer. I took the meds when I had to make that choice, because I couldn't deal with the pain, wimp that I am... And if it's ulcers that result, I'll have to deal with them... Sharon in D.C. Re: Bextra I always talk about Quality of Life. My doc lets me have anti inflamatories. Without them, I have a diminished Quality of Life. I also take Prilosec. I am not ulcer prone, but if I do become so, I will deal with it then. Fay Bayuk **300/168 10/23/01 Dr. Open RNY 150 cm Click for My Profile http://obesityhelp.com/morbidobesity/profile.phtml?N=Bayuk951061008 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 8, 2004 Report Share Posted January 8, 2004 Hi , I take 1 Bextra daily along with another drug, Cytotec, 3 times a day. While it is better to not take any NSAID, some of us, like me have chronic pain that affects my quality of life. I started taking vioxx a month or so after my RNY and at 18 mo post-op developed a pouch ulcer. I was taken off vioxx (it is one of the worst NSAIDs though I found it to be the most effective) and switched to bextra along with the cytotec. NSAIDs prevent the protective lining of the pouch from forming (my non-technical explanation) and taking the cytotec acts as a protective lining in the pouch. Bextra is also the least likely of the NSAIDs to cause ulcers. Anyways, so far so good. I've been on it for 4 months now. Preferably, its better to not take an NSAID or to do very short courses of them, but discuss with your doctor. Cindy in Va lap RNY 2/8/02 > Hello group > > I need some of your valuable experience. I had a rny w/fobi in Nov > 2002. I also have degenerative joint disease. My primary physician > has prescribed bextra for me, telling me that this is not suppose to > cause ulcers in a normal stomach and that it is the mildest of all > the nsaids. Can you guys tell me any information on this drug and > how it affects our pouch before I start taking them? Thanks for > your valuable support. I read post daily and consider your opinions > and experience very valuable in my own weight loss journey. > > > 313/156/??? > Dr. Gorospe/ Tulsa > Open rny W Fobi Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 8, 2004 Report Share Posted January 8, 2004 Hi , I take 1 Bextra daily along with another drug, Cytotec, 3 times a day. While it is better to not take any NSAID, some of us, like me have chronic pain that affects my quality of life. I started taking vioxx a month or so after my RNY and at 18 mo post-op developed a pouch ulcer. I was taken off vioxx (it is one of the worst NSAIDs though I found it to be the most effective) and switched to bextra along with the cytotec. NSAIDs prevent the protective lining of the pouch from forming (my non-technical explanation) and taking the cytotec acts as a protective lining in the pouch. Bextra is also the least likely of the NSAIDs to cause ulcers. Anyways, so far so good. I've been on it for 4 months now. Preferably, its better to not take an NSAID or to do very short courses of them, but discuss with your doctor. Cindy in Va lap RNY 2/8/02 > Hello group > > I need some of your valuable experience. I had a rny w/fobi in Nov > 2002. I also have degenerative joint disease. My primary physician > has prescribed bextra for me, telling me that this is not suppose to > cause ulcers in a normal stomach and that it is the mildest of all > the nsaids. Can you guys tell me any information on this drug and > how it affects our pouch before I start taking them? Thanks for > your valuable support. I read post daily and consider your opinions > and experience very valuable in my own weight loss journey. > > > 313/156/??? > Dr. Gorospe/ Tulsa > Open rny W Fobi Quote Link to comment Share on other sites More sharing options...
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