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In a message dated 8/21/2003 7:27:05 AM Eastern Daylight Time,

Graduate-OSSG writes:

> ? I think there is

> sufficient evidence that Vioxx has caused ulcers, but what about

> Bextra?

Bextra is an NSAID, specifically, a COX-2 inhibitor. This is the identical

classification of Vioxx. If you check the patient information sheet that comes

with Bextra, or the PDR (Physicians Desk Reference), or the MPR (Monthly

Prescribing Reference) under " Adverse Reactions " , it reads: " GI effects (upset,

pain, ulcer, bleed), edema, hypertension, rash, etc. " That means those side

effects have already been clinically seen with use of this medication.

Sandy

Boca Raton, FL

postop ~ 03/27/02

265/128

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  • 4 months later...

1. you (and I) don't have a normal stomach

2. I personally wouldn't take it unless absolutely necessary and then would

expect to be checked for ulcers every so often (since you can get ulcers that

bleed without pain).

JMHO.

Pam in Niceville

----- Bextra

> Hello group

>

> I need some of your valuable experience. I had a rny w/fobi in Nov

> 2002. I also have degenerative joint disease. My primary physician

> has prescribed bextra for me, telling me that this is not suppose to

> cause ulcers in a normal stomach and that it is the mildest of all

> the nsaids. Can you guys tell me any information on this drug and

> how it affects our pouch before I start taking them? Thanks for

> your valuable support. I read post daily and consider your opinions

> and experience very valuable in my own weight loss journey.

>

>

> 313/156/???

> Dr. Gorospe/ Tulsa

> Open rny W Fobi

>

> Homepage: http://groups.yahoo.com/group/Graduate-OSSG

>

> Unsubscribe: mailto:Graduate-OSSG-unsubscribe

>

>

>

>

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,

Is this something you will be taking long term? My dh has a pharmacy

background and what he told me is Bextra is a member of the relatively new

class of painkillers called COX-2 inhibitors. It is prescribed for the

relief of osteoarthritis, rheumatoid arthritis,ect.

COX-2 inhibitors are part of a larger group of medications called

nonsteroidal anti-inflammatory drugs (NSAIDs). All the drugs in this

category (including such familiar remedies as aspirin, Motrin, and Naprosyn)

relieve pain and inflammation by limiting the effect of a natural enzyme

called COX-2. Unlike the older NSAIDs, however, the new COX-2 inhibitors do

not interfere with COX-1, a related enzyme that exerts a protective effect

on the lining of the stomach. As a result, Bextra and other COX-2 inhibitors

are less likely to cause the bleeding and ulcers that sometimes accompany

sustained use of the older NSAIDs. Although the chances of stomach or

intestinal bleeding are low, a slight danger remains. If you are only taking

this for a short time it's probably safe. Your best bet would be to talk to

your surgeon and see what he thinks.

> Hello group

> My primary physician

> has prescribed bextra for me, telling me that this is not suppose to

> cause ulcers in a normal stomach and that it is the mildest of all

> the nsaids. Can you guys tell me any information on this drug and

> how it affects our pouch before I start taking them? Thanks for

> your valuable support. I read post daily and consider your opinions

> and experience very valuable in my own weight loss journey.

>

>

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You're right, Fay. We have to weigh these things - quality of life vs. the RISK

of ulcer. I took the meds when I had to make that choice, because I couldn't

deal with the pain, wimp that I am... And if it's ulcers that result, I'll have

to deal with them...

Sharon in D.C.

Re: Bextra

I always talk about Quality of Life. My doc lets me have anti inflamatories.

Without them, I have a diminished Quality of Life. I also take Prilosec. I

am not ulcer prone, but if I do become so, I will deal with it then.

Fay Bayuk

**300/168

10/23/01

Dr.

Open RNY 150 cm

Click for My Profile

http://obesityhelp.com/morbidobesity/profile.phtml?N=Bayuk951061008

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Hi ,

I take 1 Bextra daily along with another drug, Cytotec, 3 times a

day. While it is better to not take any NSAID, some of us, like me

have chronic pain that affects my quality of life. I started taking

vioxx a month or so after my RNY and at 18 mo post-op developed a

pouch ulcer. I was taken off vioxx (it is one of the worst NSAIDs

though I found it to be the most effective) and switched to bextra

along with the cytotec. NSAIDs prevent the protective lining of the

pouch from forming (my non-technical explanation) and taking the

cytotec acts as a protective lining in the pouch. Bextra is also the

least likely of the NSAIDs to cause ulcers. Anyways, so far so

good. I've been on it for 4 months now. Preferably, its better to

not take an NSAID or to do very short courses of them, but discuss

with your doctor.

Cindy in Va

lap RNY 2/8/02

> Hello group

>

> I need some of your valuable experience. I had a rny w/fobi in Nov

> 2002. I also have degenerative joint disease. My primary

physician

> has prescribed bextra for me, telling me that this is not suppose

to

> cause ulcers in a normal stomach and that it is the mildest of all

> the nsaids. Can you guys tell me any information on this drug and

> how it affects our pouch before I start taking them? Thanks for

> your valuable support. I read post daily and consider your

opinions

> and experience very valuable in my own weight loss journey.

>

>

> 313/156/???

> Dr. Gorospe/ Tulsa

> Open rny W Fobi

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Share on other sites

Hi ,

I take 1 Bextra daily along with another drug, Cytotec, 3 times a

day. While it is better to not take any NSAID, some of us, like me

have chronic pain that affects my quality of life. I started taking

vioxx a month or so after my RNY and at 18 mo post-op developed a

pouch ulcer. I was taken off vioxx (it is one of the worst NSAIDs

though I found it to be the most effective) and switched to bextra

along with the cytotec. NSAIDs prevent the protective lining of the

pouch from forming (my non-technical explanation) and taking the

cytotec acts as a protective lining in the pouch. Bextra is also the

least likely of the NSAIDs to cause ulcers. Anyways, so far so

good. I've been on it for 4 months now. Preferably, its better to

not take an NSAID or to do very short courses of them, but discuss

with your doctor.

Cindy in Va

lap RNY 2/8/02

> Hello group

>

> I need some of your valuable experience. I had a rny w/fobi in Nov

> 2002. I also have degenerative joint disease. My primary

physician

> has prescribed bextra for me, telling me that this is not suppose

to

> cause ulcers in a normal stomach and that it is the mildest of all

> the nsaids. Can you guys tell me any information on this drug and

> how it affects our pouch before I start taking them? Thanks for

> your valuable support. I read post daily and consider your

opinions

> and experience very valuable in my own weight loss journey.

>

>

> 313/156/???

> Dr. Gorospe/ Tulsa

> Open rny W Fobi

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