science

September 3, 2003

This is from the MSNBC web site. They are trying to help us. Maybe our

children or grandchildren will benefit from this research

Harnessing the dietary role of hormones in the body is an important step in

developing effective weight control therapies, experts say.

Click on a button above for the latest science on the so-called hunger

hormones.

Scientists have isolated the short-term hormone PYY3-36, which is secreted by

cells lining the intestines after eating. The so-called â€œthird helping hormone

â€ sends signals to the feeding circuits in the brain that convey a sense of

satiety, which reduces the urge to eat. In a small experiment, people who

received an infusion of the hormone ate one-third less over the next 24 hours

than

those who received a placebo. Researchers think a medication based on boosting

levels of the hormone might reduce overeating and between-meal snacking.

Ghrelin, named for the Hindi word for growth, was the first hunger hormone

found circulating in the blood of humans. It has been found to stimulate hunger

in rats and make people so ravenous that they eat nearly a third more food

than usual. Ghrelin has also been found to rise in the bloodstream after dieters

lose lots of weight, possibly explaining why itâ€™s so hard to keep weight off

long-term. The hormone is considered a potential new treatment for both obese

patients and those with conditions that cause a dangerous loss of appetite,

such as cancer.

Leptin is a hormone involved in the normal regulation of body weight. Itâ€™s

supposed to signal the brain to stop eating, but the signal does not get through

in some overweight people. At one point a few years ago, doctors thought

leptin could be used as a breakthrough obesity drug. So far, it has not lived up

to its promise, but a recent study showed that tiny doses of leptin taken after

weight loss could help people keep weight off.

Melanin-concentrating hormone, or MCH, is one of many compounds found to

stimulate appetite. Scientists have discovered the receptor for MCH in the human

brain, which could allow them to design drugs to block the hormoneâ€™s action.

September 4, 2003

In a message dated 9/4/2003 6:47:35 AM Eastern Standard Time, watnext@...

writes:

would love to

be proven wrong, but knowing Dr. Phil's methods, I doubt it.

He will say what is necessary to increase ratings. TV whores.

Can I use that word?

Fay Bayuk

**300/166

10/23/01

Dr.

Open RNY 150 cm

Click for My Profile

http://obesityhelp.com/morbidobesity/profile.phtml?N=Bayuk951061008

September 4, 2003

Absolutely! Do you think they'll be tacky enough to promote his new line of

supplements?

in NJ

****************************

In a message dated 9/4/2003 6:51:26 AM Eastern Daylight Time, FBayuk writes:

> He will say what is necessary to increase ratings. TV whores.

> Can I use that word?

>

September 4, 2003

If they are really trying to help us, I would hope their obesity show

with Dr. Phil would concentrate on this research rather than his

usual crap. Think that's possible? I don't. Although they may

mention these hormones, I'll bet the show will serve to perpetuate

the guilt, blame and feelings of failure for the 95% of the

population who can not lose weight and keep it off. I would love to

be proven wrong, but knowing Dr. Phil's methods, I doubt it.

in NJ

**************************

> This is from the MSNBC web site. They are trying to help us.

Maybe our children or grandchildren will benefit from this research

>

> Harnessing the dietary role of hormones in the body is an important

step in developing effective weight control therapies, experts say.

> Click on a button above for the latest science on the so-called

hunger hormones.

> >

> Scientists have isolated the short-term hormone PYY3-36, which is

secreted by cells lining the intestines after eating. The so-called

third helping hormone sends signals to the feeding circuits in the

brain that convey a sense of satiety, which reduces the urge to eat.

In a small experiment, people who received an infusion of the hormone

ate one-third less over the next 24 hours than those who received a

placebo. Researchers think a medication based on boosting levels of

the hormone might reduce overeating and between-meal snacking.

> >

> Ghrelin, named for the Hindi word for growth, was the first hunger

hormone found circulating in the blood of humans. It has been found

to stimulate hunger in rats and make people so ravenous that they eat

nearly a third more food than usual. Ghrelin has also been found to

rise in the bloodstream after dieters lose lots of weight, possibly

explaining why it's so hard to keep weight off long-term. The hormone

is considered a potential new treatment for both obese patients and

those with conditions that cause a dangerous loss of appetite, such

as cancer.

> >

> Leptin is a hormone involved in the normal regulation of body

weight. It's supposed to signal the brain to stop eating, but the

signal does not get through in some overweight people. At one point a

few years ago, doctors thought leptin could be used as a breakthrough

obesity drug. So far, it has not lived up to its promise, but a

recent study showed that tiny doses of leptin taken after weight loss

could help people keep weight off.

> >

> Melanin-concentrating hormone, or MCH, is one of many compounds

found to stimulate appetite. Scientists have discovered the receptor

for MCH in the human brain, which could allow them to design drugs to

block the hormone's action.

>

January 4, 2004

In a message dated 1/4/2004 12:34:13 PM Central Standard Time,

kristine.patrick@... writes:

I hear ya n ! I find myself watching tv shows where the celebs

give their money to charity and the charities they pick make me roll

my eyes! It is hard because there are so many worthy causes but I

want MY cause to be the most important! I think about how I felt

regarding charities before dx, and how indifferent I was towards

certain causes, especially the ones concerning health. My husband

informed me that he has designated $20.00 a month be taken out of

his paycheck and donated to CFF. He has also convinced six of his

workmates to do the same. That amount seems so small compared to

what fund raisers bring in, and I am a " bigger is better " kind of

person. However, I have changed my way of thinking to " every little

bit helps " .

Cheers,

e

My niece is a very good sports player in just about everything she does and

one year they did an article in the paper about her and they asked her lots of

question and one question they asked her was if she won the lottery what would

she do with the money and she said she would give some of it to charities and

I said what charities you should have said you would give only to the Cystic

Fibrosis Charities. She told me oh I never thought about that GEEZ HOW COULD

SHE FORGET!!!! I had to give her a hard time!! Deb A

January 4, 2004