Guest guest Posted November 29, 2001 Report Share Posted November 29, 2001 Elle: Information from Scopinaro's report states that 100% of the diabetics who participated in the study were cured of diabetes, and that the cure could not be attributed to loss of weight in and of itself, but to the " specific action of BPD on glucose metabolism. " Hess claims that Type II diabetes is cured by the BPD. You gotta give me better arguments than these to make me change my tune. Best, From Scopinaro's Report: " In fact, out of the 1773 (total series) AHS BPD patients with a minimum follow-up of one year, not only the 248 (14%) with preoperative simple hyperglycemia, nor only the 108 (6.1%) with type II diabetes mellitus manageable with oral hypoglycemics, but also the 32 (1.8%) patients with preoperative type II diabetes mellitus requiring insulin therapy, one year after BPD and permanently thereafter had normal serum glucose level without any medication and on totally free diet. Comprehensibly, this is accompanied by serum insulin levels normalization, as demonstrated by us in cross- sectional (22) and longitudinal (serum insulin in 53 AHS BPD subjects: preop. 18±10 mcU/ml; at 1 year 5.2±2.3; at 2 years 4.6±2.0; at 3 years 6.0±3.1; controls 6.9±2.6; ANOVA: each group vs. preop. <.0001) studies, as well as normalization of insulin-sensitivity (Table 6). " " Considering that about 20 percent of type II diabetes mellitus patients are not obese, and about 20 percent of formerly obese patients with type II diabetes mellitus still require insulin therapy after weight normalization by dieting, it must be concluded that simple weight loss or intraabdominal fat reduction cannot account for the observed 100 percent recovery from type II diabetes mellitus after BPD. Actually, our preoperatively diabetic patients had on the average normal serum glucose concentration already one month after operation, when the excess weight was still over 80%, this also indicating a specific action of BPD on glucose metabolism. The latter could be identified with the virtual annulment of the entero-insular axis. Indeed, serum GIP concentration shows after BPD a substantially flat curve in response to the test meal, along with normalization of basal and meal-stimulated serum insulin levels (10). " From Hess's report: " Bariatric surgery has been known to improve or cure diabetes mellitus6. With the biliopancreatic bypass and the duodenal switch we have operated on 36 diabetics, all Type II, of which 18 of them are non-insulin dependent and 18 were insulin dependent. One patient was taking as high as 500 units of insulin a day, but generally they were taking insulin in the range of 40 to 50 units per day. The non- insulin dependent patients would leave the hospital after surgery taking no medication and have continued taking no medication since their surgery. The insulin dependent diabetics would occasionally take a small amount of insulin or a hypoglycemic agent for a short time, but never more than two months following surgery. All of the above patients, after a few months and up to seven years following surgery, are taking no medication of any type for their diabetes. All of them have normal blood sugars as indicated in the graph showing the pre-operative average blood sugar and the post-operative average blood sugar on all these patients up to 5 years (Figure 8). The present glycosylated hemoglobin average for this group is 5.0% (normal reference range is 4.2%-5.9%). We can say without hesitation for the obese Type II diabetic, this surgery will cure their diabetes. " > OK I have to jump in on this. > Diabetes, even type ll diabetes, is not cured by the DS, but is ~controlled~ by weight loss. Right now there is no > cure for diabetes other than a pancreatic organ replacement. > It's important for diabetics to continue to test to make sure their blood glucose level remains low. > Although I am no longer on insulin, I'm still a diabetic and I make sure to test several times a week (fasting and after a > couple of meals where I have had starches). > Our beta cells, the insulin making cells, don't have to overwork themselves to pump out glucogen/insulin as hard > when we lose weight. Sometimes the drasticly fast weight loss can make an immediate difference to a diabetic. > > For me, I quit using insulin the first week out of the hospital because I wasn't eating very much (no duh). As my > meals increased in quantity and as I added the occasional sweet to my diet (Oreos today) I make sure I continue to > test. After the sweets this afternoon, my glucose level rose to 148 but dropped quickly. > > I'm glad my body is responding so well to surgery but I'll never be cured of diabetes. > > Elle in oregon - under 200# for the first time in decades Quote Link to comment Share on other sites More sharing options...
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