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early adrenarche

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Hi Cindy,

My son is almost 12 now, but he went into adrenarche just before his

4th birthday. My son also probably has one of the more extreme cases

of insulin resistance, as he isn't doing very well with his growth

even on GH. What I have learned is that as long as the bone age

doesn't advance, you don't really need to treat the other adrenarche

issues. Even if your son is put on an aromatase inhibitor, it will

not stop the overt signs of adrenarche such as the body odor, acne,

etc. Your doctor should do bloodwork to look at DHEA levels, and if

there is any question about those levels, an ACTH stimulation test

can be done as well. I have not heard of the risk of tumors

associated with elevated IGF-1 levels, but there is a risk of Type 2

diabetes, as we are dealing with this issue now.

Kim C.

> Subject: early adrenarche

>

> Has anyone else's kids had very early adrenarche or insulin

> resistance?

> n just turned 5 and he's had underarm odor for over two years

> now.

> Dr. H talked about that at the convention but didn't mention anything

> being done about it. He just got some tests done on hormone levels, so

> we'll see.

>

> Cindy

>

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