Guest guest Posted October 9, 2001 Report Share Posted October 9, 2001 The best data that I've seen on this, come from Dr. Cade. His graphs show how the protein fragments that are probably derived from gluten, disappear gradually from the patient's system after appropriate diet intervention has been started. The speed of the process depends on several factors. One of the most important was, I believe, chain length: Some molecule fragments are more likely than others to get stored in body tissue in ways that delay the " detoxification " process. The speed should also depend on enzyme activity (in supplement form, or if natural production of proteases picks up again). Dr. Cade demonstrated that the process can be accellerated by dialysis, this is apparently how his interest in the peptide issue started: Some schizophrenic kidney patients improved remarkably from their schzophrenia each time they went through dialysis. Ordinarily, this kind of protein fragment is very short-lived in the body. The half-life of morphine is just a matter of hours. When the normal protease enzymes are missing, it takes longer. We'be been through hundreds of small diet infringements as well as some big ones (up to half a glass of milk). To judge from my son's pupils and his general behaviour, the first phase (with strongly elevated peptide levels) will normally take 1-4 days, and the second phase (with peptide levels still higher than average) will take at least 1-3 weeks. For a patient that has been on a " normal " G & C diet, the quantities stored in the body in less accessible form will be much higher, but I would expect most of the peptide excess to disappear within 2-4 months. This is just a guideline: We've seen several examples where peptide levels have not appeared to drop AT ALL during the first year on GFCF diet, while the parents made every effort to do everything right. One very important reason why it can take very long to get rid of the last protein fragments, is that it takes time to do the diet properly. * We believed that it took us a couple of weeks to go 100% GFCF. * In actual fact, we kept giving him up to 1000 milligrams of gluten every day for the first 5-6 years. There were several hidden sources. It's concievable that even a very small, steady intake (10-100 mg/day or even less) is all that it takes to maintain peptide levels that are significantly elevated. Yours sincerely n Klaveness Gluten in the body > I recently took my son to an experienced allergist who is au fait with the casein/gluten issues, but claimed that there is no evidence that the effects of gluten can take months (some say up to a year) to leave the body - he says it would happen much more quickly. Does anybody know where this theory originates from and whether there is any scientific evidence to back it up? > > Thanks > > Anne Quote Link to comment Share on other sites More sharing options...
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