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Re: Digest Number 3081

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Hi There

Can you kindly take us off the email list.

Regards

Dan & Anne

Re: Tonight

>

> Hey Jodie. Thanks for asking. Everyone seems to be holding up.

> Except, my dh and I went out on a date (first one in about 3 months)

> and I ate so much at dinner - now my stomach hurts! LOL Ugh - I feel

> like you do after Thanksgiving. I can't even go to sleep! LOL

>

> Oh - and the cleaning and sanitizing? Well, I left the couch cushions

> outside this afternoon in the sun. Then, I left a message for an

> upholstery cleaner to come on Monday. Hopefully, they will get the

> message. My big guy did a number on my couch. My dh and I while out

> and about this afternoon looked at couches - we asked the salesman if

> the leather ones were vomit proof. The salesman was kinda taken-a-

> back though and looked at us as if we were strange. Maybe it was the

> galic and wine on my breath. LOL My dh and I just started laughing.

>

> Anyway, I'm hoping Ian doesn't get whatever it was. I couldn't

> stomach it right about now. LOL

>

> Hope all is well with you. Thanks again for asking.

>

> Goodnight.

>

> - H

>

>

>>Inga,

>>

>>This is a tricky subject and I hope I explain my thoughts to you in

>>a clear manner. The Lupron you are using with your son is to delay

>>puberty. That means it delays the onset of facial hair, increase in

>>size of the testicles, deepening of the voice, and all the other

>>stuff that goes along with puberty. It is delayed for several

>>reasons, one being that a boy (or girl) showing these signs of

>>development at an early age will stand out and look too different

>>than his peers. It is also a time when growth speeds up - you know,

>>like when you look at a teen in July (especially boys) and then see

>>him again in September and it looks like he has grown several feet!

>>

>>Now, as Pat explained, Lupron, Zoladex, Lupron Depot, etc. are not

>>associated with adrenarche which is responsible for advancing bone

>>age. For that you would need to use Armidex, an aromatase

>>inhibitor. This drug reduces and/or stops the production of

>>estrogen, an enemy for a child with growth problems because of the

>>advancement of bone age. As you know, once those growth plates

>>fuse, no further growth can be obtained.

>>

>>Max showed signs of both puberty and adrenarche when he was in 5th

>>grade, I believe. He immediately began taking Armidex and his bone

>>age, which was catching up to his chronological age, began to slow

>>down. As his chronological age went on, his bone age slowed down to

>>the point where he is now 3 years delayed. He is 17, but his bone

>>age is 14. That is great because it will give him that much more

>>time to grow. (I think he is almost 5'5 " now!)

>>

>>Soon after starting the Armidex, Dr. H. decided to start him on

>>Zoladex. Because of Max's uncontrolled and precarious anxiety at

>>that time, she thought it would be a better choice than Lupron. The

>>Zoladex would be placed every 86 days vs. the Lupron which would be

>>painful and need to be injected every 28 days. Even though she had

>>never placed the pellet herself before, we trusted her and let her,

>>once again, use Max as her " guinea pig. "

>>

>>The medications worked very well. We happily followed the routine

>>until a little over a year ago. Max at that point was in high

>>school and looked like a baby compared to the huge and developed

>>boys he was in school with. The decision was made to stop the

>>Zoladex so that he could go into puberty and look more like his

>>peers. The timing was right. Kids can be cruel and we did not want

>>him teased because he still looked so young, besides being so much

>>shorter than the others.

>>

>>But we continued to use the Armidex and we still do.

>>

>>Max's voice is deep, he has hairy legs, he shaves now and I know

>>that his testicular development has advanced. When he was in the

>>hospital last fall, I had to help him use the bathroom because he

>>was too weak to go by himself and I got a good look. Man, was I

>>surprised! I was actually embarrassed 'cause he looked like a MAN!

>>He facial features are more sculpted, he has acne, he has muscles

>>and he just looks older all around. (The acne got to the point

>>where I had to take him to the doctor in August for medication. Now

>>that is under control, thank goodness.)

>>

>>My point in all of this long message is that socially it is

>>important to consider puberty and the correct time to let it

>>happen. But medically it is important to keep that estrogen from

>>developing too rapidly so our kids have more time to grow.

>>

>>You mentioned that you have seen weight gain with the increased

>>Lupron dose, too. Yes, that can be a side effect, but you should

>>also have him checked for Type 2 diabetes. Our kids are at risk for

>>that condition and the weight gain can be a sign of that as well.

>>An oral glucose tolerance test would be the thing to do for that.

>>

>>I hope I have helped you understand this better. It is so confusing

>>and even I get mixed up every now and then. Gosh, there is so much

>>to remember and to understand.

>>

>>Jodi Z

>>

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