RTM: Kovatsi & Tsouggas: aspartame affects magnesium Sept 2001 11.22.1 rmforall

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RTM: Kovatsi & Tsouggas:

aspartame affects magnesium Sept 2001 11.22.1 rmforall

http://groups.yahoo.com/group/aspartameNM/message/760 long version

Magnes Res 2001 Sep;14(3):189-94

The effect of oral aspartame administration on the

balance of magnesium in the rat.

Kovatsi L, Tsouggas M.

Laboratory of Forensic Medicine & Toxicology, Faculty of Medicine

Aristotle University of Thessaloniki, Greece. kovatsi@...

The aim of the present work was to determine the effect of aspartame

administration on the excretion of magnesium and its distribution

in the various rat tissues and organs. The present results have shown

that aspartame administration influences the balance of magnesium

in the organism, since in some organs and tissues (heart, lungs,

kidneys, adrenals, jejunum, hair and blood) it is accumulated, while

other organs (liver and testes) are deprived of it.

Aspartame administration also affects the excretion of magnesium

from the organism, since it decreases the concentration of magnesium in

both urine and feces. PMID: 11599551

L. Kovatsi is co-author of three similarly highly technical studies,

recently listed in PubMed,

while M. Tsouggas has no other papers listed.

I have added, at the end of this post, some information

to show that magnesium is a well developed research area.

Of course, like virtually any aspect of medical research,

it can be readily turned into health fraud, whether by

corporate machinations or by the well known plethora

of other quackeries.

Good scientists always always have in mind what they are trying to

establish. Better scientists welcome the process of having to

change their minds in the face of obdurant evidence. So, as a layman,

I regard it as significant that biochemists in Greece are examining the

details of aspartame metabolism. I'm guessing that they are laying

some groundwork for establishing aspartame toxicity as a

well recognized topic for reseach and medical practice.

We behold in the last three years the typical expansion of an evidence-

based medical field, as detailed biochemical investigations and

competent reports by eminent clinicians converge to establish

the reality of aspartame toxicity. As the decades-long campaign,

well-funded, adroit, and very succesful, by industry PR to cast the

issue as a case of cranks and mistaken professionals assailing a

completely innocent, beneficial product,

" the most tested food additive in history, " finally flounders

in a stormy sea of public protest and stubborn facts, the

current meager trickle of research will fast become a mainstream

effort, obviously credible and officially sanctioned, at last,

for the enormous relief of completely gratuitous public misery.

By no means a " food additive " , " Generally Regarded As Safe " ,

aspartame on the face of it is a potent drug,

soon to be widely branded as pernicious and prevalent

a poison as nicotine or mercury.

Magnesium is not in the detailed index of this exhaustive review,

with over 600 references from standard medical research, sold by

http://amazon.com and & Noble:

http://groups.yahoo.com/group/aspartameNM/message/669

Rich Murray: :

" Aspartame Disease " 1038 page expert magnum opus 7.5.1 rmforall

http://groups.yahoo.com/group/aspartameNM/message/752

RTM: Newman & Lipton:

aspartame triggers & worsens migraine 11.17.1 rmforall

Headache 2001 Oct;41(9):899-901

Migraine MLT-Down: An Unusual Presentation of Migraine in Patients With

Aspartame-Triggered Headaches.

[Merck 10-mg Maxalt-MLT, for migraine, has 4 mg aspartame.]

Newman LC, Lipton RB.

Headache Institute, St. Lukes-Roosevelt Hospital Center, New York

NY Department of Neurology

Albert Einstein College of Medicine, Bronx, NY

Innovative Medical Research

http://groups.yahoo.com/group/aspartameNM/message/652

Rich Murray: : fibromyalgia & aspartame & MSG 6.27.1 rmforall

Ann Pharmacother 2001 Jun;35(6):702-6

Relief of fibromyalgia symptoms following

discontinuation of dietary excitotoxins.

JD, Terpening CM, Schmidt SO, Gums JG.

Malcolm Randall Veterans Affairs Medical Center, Gainesville, FL, USA.

Excellent 5-page review by H.J. in " Townsend Letter " ,

Jan 2000, " Aspartame (NutraSweet) Addiction "

http://www.dorway.com/tldaddic.html http://www.sunsentpress.com/

H.J. , M.D. HJmd@... sunsentpress@...

Sunshine Sentinel Press P.O.Box 17799 West Palm Beach, FL 33416

fax

http://groups.yahoo.com/group/aspartameNM/message/346

WebMD: Barclay: Barth:

survey shows aspartame hurts memory in students 11.9.00

http://www.psy.tcu.edu/psy/barth.htm

M. Barth Department of Psychology t.barth@...

Texas Christian University TCU Box 298920 Fort Worth, TX 76129

Chairman, Physiological Psychology

http://groups.yahoo.com/group/aspartameNM/message/689

Rich Murray: Karikas: aspartame binding to DNA:

Clinical Biochemistry July 1998 7.27.1 rmforall

Karikas GA, Schulpis KH, Reclos GJ, Kokotos G.

Dept. of Chemistry, University of Athens, Greece

http://www.chem.uoa.gr gkokotos@...

Measurement of molecular interaction of aspartame and

its metabolites with DNA. Clin Biochem. 1998 Jul;31(5):405-7.

A radioactive tracer study proves that the methanol from a low dose of

of aspartame binds formaldehyde, a deadly cumulative poison, into

tissues: Trocho C et al, June 26 1998, Life Sci, 63(5), 337-349.

http://ww.presidiotex.com/barcelona/index.html

Two teams find hot aspartame releases DKP, a potent carcinogen:

Food Addit Contam 2000 Oct; 17(10): 821-7

Simultaneous formation and detection of the reaction product of

solid-state aspartame sweetener by FT-IR/DSC microscopic system.

Lin SY, Cheng YD

Biopharmaceutics Laboratory,

Department of Medical Research & Education

Veterans General Hospital-Taipei, Shih-Pai, Taiwan,

Republic of China. sylin@...

and

J Pharm Sci 1998 Apr; 87(4): 508-13

Hydration and dehydration behavior of aspartame hemihydrate.

Leung SS, Padden BE, Munson EJ, Grant DJ

Department of Pharmaceutics, College of Pharmacy,

University of Minnesota, Minneapolis 55455-0343, USA.

Sophie S. Leung, PhD

Dolores J. Grant, PhD grant1@...

Lennart Hardell, M.D., PhD, in 1999 reported in Sweden that both

cell phone use and heavy aspartame use correlate with increased

brain cancers http://www.medscape.com/MedGenMed/braintumors

lennart.hardell@... +46 19 602 15 46

There has for years been a competent Greek anti-aspartame website:

http://users.westnet.gr/~cgian/aspartame.htm

Costas Giannakennas, MD

http://www.execpc.com/~magnesum

THE MAGNESIUM WEB SITE

is maintained by: Mason

P.O. Box 1417

, CA 95363

[Three books cover international symposia in 1976, 1988, and 2000.

As it happens, there are a number of Greek researchers.]

http://www.execpc.com/~magnesum/books.html

Magnesium Research

Keep updated with the latest research in Magnesium

The Biological Chemistry of Magnesium

by J. A. Cowan (Editor)

Emphasizing interactions at the molecular level, reviews the current

understanding of magnesium biochemistry, especially the pivoltal role

of magnesium ion in nucleic acid biochemistry. The topics include

magnesium as the catalytic center of RNA enzymes, magnesium-dependent

enzymes in the general metabolism, the genetics and molecular biology

of magnesium transport systems, and the regulation of cytosolic

magnesium ion in the heart.

Addressed to graduate students and non-specialists in biochemistry,

biotechnology, pharmaceutical sciences, and related disciplines.

Annotation copyright Book News, Inc. Portland, OR.

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Rich Murray, MA Room For All rmforall@...

1943 Otowi Road, Santa Fe NM USA 87505

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