RE: Gentamicin, the new kind!/LINDA

[Guest guest]

Thank you so very much! Love, n Rojas

Re: Gentamicin

Hi all,

Gentamicin has been found to cause the gene to read

passed the stop, thereby producing normal cftr in

those with the stop mutations. (I think I got that

right). There is the worry that using gentamicin as

is could cause toxicity over the long run.

Those with stop mutations will find the following

article interesting about a new pill being tested

called PCT128. It does the same thing without the

toxicity of gentamicin.

Popping a pill could fix gene defect

http://www.newscientist.com/news/news.jsp?id=ns99994269

C

Mommy to Mick and Alli, 4 yo twins wcf (both mutations

are stop!)

-------------------------------------------

The opinions and information exchanged on this list should IN NO WAY

be construed as medical advice.

PLEASE CONSULT YOUR PHYSICIAN BEFORE CHANGING ANY MEDICATIONS OR TREATMENTS.

------------------------------------

------------------------------------------------------------------------------

[Guest guest]

,

That was a very interesting article. Eilish also has a stop mutation so

I really do hope this will prove to be a help.

(Australia)

Re: Gentamicin, the new kind!/LINDA

Thank you so very much! Love, n Rojas

Re: Gentamicin

Hi all,

Gentamicin has been found to cause the gene to read

passed the stop, thereby producing normal cftr in

those with the stop mutations. (I think I got that

right). There is the worry that using gentamicin as

is could cause toxicity over the long run.

Those with stop mutations will find the following

article interesting about a new pill being tested

called PCT128. It does the same thing without the

toxicity of gentamicin.

Popping a pill could fix gene defect

http://www.newscientist.com/news/news.jsp?id=ns99994269

C

Mommy to Mick and Alli, 4 yo twins wcf (both mutations

are stop!)

-------------------------------------------

The opinions and information exchanged on this list should IN NO WAY

be construed as medical advice.

PLEASE CONSULT YOUR PHYSICIAN BEFORE CHANGING ANY MEDICATIONS OR

TREATMENTS.

------------------------------------

------------------------------------------------------------------------

------

[Guest guest]

,

Only about 10% of the cf population have stop

mutations (or so I've been led to believe), so it

is not a " cure " for cf, but for those with stop

mutations, a pill like PTC124, or a modified and

non-toxic form of gentamicin, could very well prove

to be close to being one. Let's all hope it pans

out, and keep on fighting the big fight for the rest

of our cf brothers and sisters.

hugs,

C

Mommy to Mick and Alli, 4 yo twins wcf

--- Baxter wrote:

> ,

>

> That was a very interesting article. Eilish also

> has a stop mutation so

> I really do hope this will prove to be a help.

>

> (Australia)

>

> Re: Gentamicin, the new

> kind!/LINDA

>

>

> Thank you so very much! Love, n Rojas

> Re: Gentamicin

>

>

> Hi all,

>

> Gentamicin has been found to cause the gene to

> read

> passed the stop, thereby producing normal cftr in

> those with the stop mutations. (I think I got that

> right). There is the worry that using gentamicin

> as

> is could cause toxicity over the long run.

>

> Those with stop mutations will find the following

> article interesting about a new pill being tested

> called PCT128. It does the same thing without the

> toxicity of gentamicin.

>

> Popping a pill could fix gene defect

>

>

http://www.newscientist.com/news/news.jsp?id=ns99994269

>

> C

> Mommy to Mick and Alli, 4 yo twins wcf (both

> mutations

> are stop!)

>

>

> -------------------------------------------

> The opinions and information exchanged on this

> list should IN NO WAY

> be construed as medical advice.

>

> PLEASE CONSULT YOUR PHYSICIAN BEFORE CHANGING ANY

> MEDICATIONS OR

> TREATMENTS.

>

> ------------------------------------

>

>

>

>

>

------------------------------------------------------------------------

> ------

>