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Re: Ambry Genetic Testing

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> Hello to the CF Support Group,

>

> I'm just curious how many families were diagnosed through Ambry

Genetics in CA.

>

> Henry, 6-year-old with CF, had the basic (I believe, 75 genes

tested for) genetic screening from Genzyme in 1998 and was positive

for dual DF508.

>

> Then, years later, I read about Ambry Genetics in a CFF Newsletter

article explaining that their genetics test checked for 800-900 of

the known CF genes.

They the Genzyme test looks for the most common mutations. They

first ran the Genzyme analysis on my son and found one common

mutation G551D. I insisted on a CF consult with our pediatrician and

the CF doctor had the Ambry test run. The Ambry caught the second

mutation which was rare. Surprisingly the Ambry test which is based

out of CA ( we are in MA) took far less time to get the results back

than did the Genzyme test which is based in MA as well. Insurance

did pick up the cost for bosth tests. SOmeone in this group wrote me

afterwards and said Hopkins has an extensive mutation test as

well.

jan

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