Guest guest Posted December 13, 2004 Report Share Posted December 13, 2004 Probably a silly question but here goes : As my previous pancreatitis was not caused by excessive alcohol, can someone tell me exactly why alcohol is such a taboo for those dealing with Acute Pancreatitis. I don't want moral lectures, as if anyone would!, but just the plain facts of how drinking may affect the pancreas. The reason I ask is that I MAY have 1 beer at New Year... Secondly, I have seen in a few posts recently suggesting to try to avoid stress amongst other things. Is stress directly related to the onset of Pancreatitis in anyone's experience? Both my surgeon and GP say work stress (Bank Manager) is unrelated to my prior condition, but as I will be returning to work in January after 7 months off I wish to avoid any triggers in the future (yes, and that includes alcohol!) Colin Scotland Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 13, 2004 Report Share Posted December 13, 2004 Hi Colin! Alcohol: my understanding is that the alcohol itself is a poison to the cellular and molecular action of the pancreas. That is, metabolizing the liquid results in certain byproducts that destroy the cells which cause the leakage and activation of enzymes inside of the pancreas instead of in the duodenum where it is suppose to happen. This release and activation of enzymes inside of the pancreas causes more damage to cells which creates a viscious cycle. Now when a person has a perfectly healthy pancreas, he or she is able to tolerate a certain amount of cellular damage, and the metabolism is much more efficient. However, when you have a less than perfect pancreas, you are more likely to suffer less efficient metabolism and even if your metabolism is good, you are less likely to tolerate the damaged cells that a healthy pancreas could. Also, it is thought that alcohol creates protein plugs in your ducts so that if you are already narrowed from disease, you are more likely to suffer a complete blockage of juice flow after drinking alcohol. Basically, you most likely will tolerate a few drinks witout immediate affect but, the long term, cumulative effect will probably mean a quicker " death " to the pancreas. However, even though you may not have an immediate reaction one time, there is always a chance that the next time you will, that this will create an actual case of acuter pancreatitis and that this acute pancreatitis will fulminate into the systemic kind which is deadly. If a person knows that he / she has a history or pancreatitis, it is best to avoid creating short term and long term damage to the pancreas. But like all things in life, it is a trade-off and you must prioritorize your decisions. One beer at New Years most likely won't kill you, but it is a drink that you must take being aware of the potential risks. One hypothesis that I read posits that the alcohol relaxes the sphincter of Oddi which allows bile and activated pancreas enzymes to backflow into the pancreas ducts which then causes tissue damage and the resulting inflamamtion, possible cyst formation and pain issues. Stress: My take on this is that stress doesn't cause the problem but it certainly exacerbates it. Both physical and mental stress can tax the system and when you have natural stress hormones in your blood stream it activates the pancreas to release its juices (after all you need energy to combate stress). So whenever you feel hungry or want to eat, your pancreas puts out juice which causes enzyme release which increases pain which again creates a viscious cycle. Just like any other part of the body that is less than perfect (except muscles I guess), you want to try to reduce its functioning in order to preserve it - basically you are babying it along to make it to the end. Laurie Quote Link to comment Share on other sites More sharing options...
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