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Re: Inheritance question

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Hold on: there is a link for this:

http://www.genetics.com.au/Genetics2004/FactSheets/18.asp

and besides, the pictures are charming! Love, n

Inheritance question

If someone has CF and they have a child will that child have CF or

what are the chances?

Family is wondering

thanks

-------------------------------------------

The opinions and information exchanged on this list should IN NO WAY

be construed as medical advice.

PLEASE CONSULT YOUR PHYSICIAN BEFORE CHANGING ANY MEDICATIONS OR TREATMENTS.

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Hi ,

Let's say that " Parent A " has CF. If " Parent A " has CF then with each

pregnancy, " Parent A " will have a child that is always a carrier

(because each child will always inherit a CF gene from " Parent A " ).

If " Parent A " has CF but " Parent B " does NOT have CF -- or is NOT a

CF carrier -- then each child will only be a carrier, but each child

will NOT have CF.

However, if " Parent A " and " Parent B " both have CF, then all children

will have CF (because each child inherits a CF gene from " Parent A "

and " Parent B " ).

Now, if by chance " Parent A " has CF and " Parent B " is a CF carrier,

then each child has a 75% chance of having CF (because each child

automatically inherits a CF gene from " Parent A, " and there's a 25%

chance of inheriting a CF gene from the carrier " Parent B " ).

Or is that 75% supposed to be 50%? Well, the scenarios still stand

correct, it's just my percentage that may be off by 25%. :)

Kim

Mom to (24 with CF) and (21 without CF, though is likely

a carrier)

> If someone has CF and they have a child will that child have CF or

> what are the chances?

> Family is wondering

> thanks

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If a person with cf has a child, the child will definately get the

cf gene from the parent with cf, and has a 1 in 25 chance of getting

a defective cf gene from the other parent (in the U.S., at least,

where one of every twenty-five people in the general population

carry one faulty cf gene.) So, basicly, the child has about a 4%

chance of having cf.

If the other parent is a carrier of a cf gene (genetic testing can

be done to find out, and while it isn't 100% accurate, it's pretty

good) then the chance of the child having cf jumps up to 50%.

That said, most people with cf don't have children. Most men with

cf are sterile and most women with cf have difficulty becoming

pregnant.

Of course, if you talk to actual families of children with cf, you

will get the distinct impression that statistics play no part in cf

at all. Although there is only a one in four chance of two carriers

having a child with cf with each pregnancy, several couples have had

more than one child with cf and none without.

It's like saying that there is a very low probability that you will

be struck by lightning, and an even lower chance that you will be

struck twice. It's not much consolation to know that while you are

lying electrified, on the grass, smelling your singed hair, for the

second time. :/

~

> If someone has CF and they have a child will that child have CF or

> what are the chances?

> Family is wondering

> thanks

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; that was pretty good! If awe-inspiring! Love, n

Re: Inheritance question

If a person with cf has a child, the child will definately get the

cf gene from the parent with cf, and has a 1 in 25 chance of getting

a defective cf gene from the other parent (in the U.S., at least,

where one of every twenty-five people in the general population

carry one faulty cf gene.) So, basicly, the child has about a 4%

chance of having cf.

If the other parent is a carrier of a cf gene (genetic testing can

be done to find out, and while it isn't 100% accurate, it's pretty

good) then the chance of the child having cf jumps up to 50%.

That said, most people with cf don't have children. Most men with

cf are sterile and most women with cf have difficulty becoming

pregnant.

Of course, if you talk to actual families of children with cf, you

will get the distinct impression that statistics play no part in cf

at all. Although there is only a one in four chance of two carriers

having a child with cf with each pregnancy, several couples have had

more than one child with cf and none without.

It's like saying that there is a very low probability that you will

be struck by lightning, and an even lower chance that you will be

struck twice. It's not much consolation to know that while you are

lying electrified, on the grass, smelling your singed hair, for the

second time. :/

~

> If someone has CF and they have a child will that child have CF or

> what are the chances?

> Family is wondering

> thanks

-------------------------------------------

The opinions and information exchanged on this list should IN NO WAY

be construed as medical advice.

PLEASE CONSULT YOUR PHYSICIAN BEFORE CHANGING ANY MEDICATIONS OR TREATMENTS.

------------------------------------

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