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Pernille has enough growth hormone in her system. The question is: will she get

any effect

of using growth hormone?

Love from Stine mom to Kristoffer 5 and Pernille 3 RSS

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Stine ... I am certainly not the expert here but from what I know, most

RSS kids aren't deficient but benefit greatly from still taking it!

Others will respond I am sure!

Dawna

>

> Pernille has enough growth hormone in her system. The question is:

will she get any effect

> of using growth hormone?

>

> Love from Stine mom to Kristoffer 5 and Pernille 3 RSS

>

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Stine,

I think it was Dr. Stanhope from Great Ormond Street Hospital in

London who said that our kids do produce growth hormone within the

normal range, but they do not use it efficiently. (I'm sure if I got

it wrong, someone will correct me.) That means that our kids need

more gh than the " normal " child in order to grow. And to catch up in

their growth. Remember, they start out behind and need that extra

help to catch up.

Jodi Z

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  • 1 month later...

Jeanie,

Most of our RSS kids do produce enough growth hormone, but they do not

use what they have efficiently. They need the extra gh to maximize

what they already have and to achieve catch-up growth. This cannot be

done, according to Drs. Harbison and Stanhope, without first achieving

catch-up growth through caloric replenishment. The caloric deficit

must first be made up through eating or g-tube and then the child will

start to grow and appear to be catching up. That growth will

eventually flatline and then gh is started.

Does this help at all?

Jodi Z

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Yes. I am now wondering how old our kids are when they start to consider GH. I

just want to make sure that we don't " miss the boat " , so to speak. I think the

Geneticist that diagnosed Brockton was a little miffed that I want to see Dr.

Harbison. Also, how important is an endocrinologist at this stage? They said

that the Endo. involved in his case sees no reason to see him right now. I just

don't know how concerned I should be and if I should be pressing the issue. Any

advice and knowledge on these subjects is, of course, GREATLY appreciated!

Thank you!

Jeanie.......Brockton (16 mo. actual age, 13 1/2 corrected age, RSS) and

's (18) mom

Jodi Zwain wrote:

Jeanie,

Most of our RSS kids do produce enough growth hormone, but they do not

use what they have efficiently. They need the extra gh to maximize

what they already have and to achieve catch-up growth. This cannot be

done, according to Drs. Harbison and Stanhope, without first achieving

catch-up growth through caloric replenishment. The caloric deficit

must first be made up through eating or g-tube and then the child will

start to grow and appear to be catching up. That growth will

eventually flatline and then gh is started.

Does this help at all?

Jodi Z

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You won't miss the boat with starting gh. There are some who start

at age 2 or 3 and others who don't start until several years later.

It depends on several factors:

-caloric repletion and catch-up growth from making up the calories

-the flatlining of the catch-up growth

-the age of your child when you are able to get to a knowledgable

endo, who, by the way, does not necessarily have to be Dr. H.,

although she is an expert on RSS

-blood sugar issues that may or may not exist in your child

-the parents' readiness or willingness to use gh

-and, I'm sure, other factors I just cannot think of at this point

in time.

Endocrinologists like to see patients at an early age so that they

can begin tracking their growth and monitor eating and other changes

in the body. Sometimes blood sugar/ketone issues do not arise at a

young age, but will pop up in the preschool years. The endo will

keep records of the child's weight/height/growth velocity, track

asymmetry if it exists, watch for signs of adrenarche (some people

see it in babies or toddlers, believe it or not), etc.

Jeanie, you are not running out of time. Please don't feel as if

you have to see someone yesterday. You are taking Brockton to

doctors who are keeping an eye on his growth and other issues, so

that is good. You should record any information they give you,

including height and weight, growth velocity, etc. When you do get

to an endocrinologist, that information will come in handy, helping

the endo to see a pattern.

The geneticist, by the way, may be a bit out of sorts because

geneticists tend to " lose " patients once they start with endos.

They like to keep track of their patients and offer advice and

guidance, too. Some keep going to the geneticist, some do not.

It's your choice.

Jodi Z

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Hi Jeanie

I have to second what Jodi Z said. Some kids start around the ages of 2-5, my

son didn't start GH until he was 8. I would have liked to have started earlier,

but there were several factors involved. First we didn't even KNOW there was a

thing wrong with Adam until he was 2 years old. NO ONE said anything was amiss

when he was an infant/baby.

Once we started to figure there was something wrong, our doctors here in Canada

said there was nothing they could do. Once THAT endo retired, the new one

started to give out GH. It took me another year to convince Adam's father to

allow the GH and so we started at 8. I remember asking Dr. H. if that age was

too late and she said no way!

So relax, do all the necessary steps (like calorie intake) first and get

Brockton on the right path. If the endo is saying nothing can be done, well see

Dr. H. or another endo. You have time and you will do what is best for Brockton!

Oh I should say, Adam's projected height as an adult WITHOUT GH was 4'7 " ; he's

now 4'8 " at the age of 13 so I have now been guaranteed 5 feet for sure and

probably more than that.

Deb

Re: Re: Growth hormone

Yes. I am now wondering how old our kids are when they start to consider GH.

I just want to make sure that we don't " miss the boat " , so to speak. I think

the Geneticist that diagnosed Brockton was a little miffed that I want to see

Dr. Harbison. Also, how important is an endocrinologist at this stage? They

said that the Endo. involved in his case sees no reason to see him right now. I

just don't know how concerned I should be and if I should be pressing the issue.

Any advice and knowledge on these subjects is, of course, GREATLY appreciated!

Thank you!

Jeanie.......Brockton (16 mo. actual age, 13 1/2 corrected age, RSS) and

's (18) mom

Jodi Zwain wrote:

Jeanie,

Most of our RSS kids do produce enough growth hormone, but they do not

use what they have efficiently. They need the extra gh to maximize

what they already have and to achieve catch-up growth. This cannot be

done, according to Drs. Harbison and Stanhope, without first achieving

catch-up growth through caloric replenishment. The caloric deficit

must first be made up through eating or g-tube and then the child will

start to grow and appear to be catching up. That growth will

eventually flatline and then gh is started.

Does this help at all?

Jodi Z

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Okay. Thanks. I'm still a little freaked out by the fact that Brockton lost

weight last week. He's been following an upward curve right along but now he's

got this " glitch " . I'm hoping when I take him back tomorrow he'll be over 16

lbs. How nice that would be.

Deb wrote: Hi Jeanie

I have to second what Jodi Z said. Some kids start around the ages of 2-5, my

son didn't start GH until he was 8. I would have liked to have started earlier,

but there were several factors involved. First we didn't even KNOW there was a

thing wrong with Adam until he was 2 years old. NO ONE said anything was amiss

when he was an infant/baby.

Once we started to figure there was something wrong, our doctors here in Canada

said there was nothing they could do. Once THAT endo retired, the new one

started to give out GH. It took me another year to convince Adam's father to

allow the GH and so we started at 8. I remember asking Dr. H. if that age was

too late and she said no way!

So relax, do all the necessary steps (like calorie intake) first and get

Brockton on the right path. If the endo is saying nothing can be done, well see

Dr. H. or another endo. You have time and you will do what is best for Brockton!

Oh I should say, Adam's projected height as an adult WITHOUT GH was 4'7 " ; he's

now 4'8 " at the age of 13 so I have now been guaranteed 5 feet for sure and

probably more than that.

Deb

Re: Re: Growth hormone

Yes. I am now wondering how old our kids are when they start to consider GH.

I just want to make sure that we don't " miss the boat " , so to speak. I think

the Geneticist that diagnosed Brockton was a little miffed that I want to see

Dr. Harbison. Also, how important is an endocrinologist at this stage? They

said that the Endo. involved in his case sees no reason to see him right now. I

just don't know how concerned I should be and if I should be pressing the issue.

Any advice and knowledge on these subjects is, of course, GREATLY appreciated!

Thank you!

Jeanie.......Brockton (16 mo. actual age, 13 1/2 corrected age, RSS) and

's (18) mom

Jodi Zwain wrote:

Jeanie,

Most of our RSS kids do produce enough growth hormone, but they do not

use what they have efficiently. They need the extra gh to maximize

what they already have and to achieve catch-up growth. This cannot be

done, according to Drs. Harbison and Stanhope, without first achieving

catch-up growth through caloric replenishment. The caloric deficit

must first be made up through eating or g-tube and then the child will

start to grow and appear to be catching up. That growth will

eventually flatline and then gh is started.

Does this help at all?

Jodi Z

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  • 4 weeks later...

Hi Aidan's mom!!

Welcome to the group!! My name is Pat, and I am g-ma to .

just turned 4 years old in Dec. He currently weighs 28# 10oz (13kg) and

measures 35.8 " (91cm) tall.

Actually, it is my understanding that GH (Growth Hormone) does not rule

growth in the human body until on or about the age of 2. Caloric intake

does. So, most important at this age, is making sure that Aidan is getting

enough calories to complete his catch-up growth.

Completion of caloric catch-up growth can be different for each child. For

my g-son, , it was determined that his " caloric catch-up " was

attained when he stopped growing taller, but continued to gain weight, for a

period of several months. His growth curve flat-lined while his weight curve

continued to rise.

Children on GHT usually increase their current growth velocity by 1.5 to 2

times. You need to be sure that Aidan will be able to gain weight at that

same increased rate.

Our first Endo, working with old information, didn't believe that GHT would

make any real difference for an RSS child. She agreed to a 6-8 month " trial "

period, but said that she would stop treatment if he didn't show

" significant " results. This was when was only 15 months of age. When

the 8 months would have been up, wouldn't have even been two. Not a

" fair " trial, so we chose to work on his " catch-up growth " and wait until

later to start him.

How long is Aidan?? How much does he weigh? Do you have any problems with

feeding him?? Have you had any problems with blood sugars, hypoglycemia, or

relux?? All of these are part of the decision making process.

Hope this helps answer your questions/

Pat (g-ma to , RSS, 4 yrs old, 28# 10.6oz, 35 " , G-Tube, GHT)

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