Guest guest Posted January 19, 2010 Report Share Posted January 19, 2010 My thoughts and prayers are with him, I hope all goes well and he is up and about in no time. Ken Overman To: Breathe-Support Sent: Tue, January 19, 2010 5:05:05 PMSubject: Steve Knipstein Just wanted to report that Steve is currently in surgery having a right single lung transplant at Brigham and Womens Hospital in Boston. Surgery started at about 6pm eastern time and will be about 6 hours. Will post any further info as I hear it. I know that Steve and his family will appreciate any prayers and loving thoughts sent their way! Beth Moderator Fibrotic NSIP 06/06 Dermatomyositis 11/08 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 20, 2010 Report Share Posted January 20, 2010 Why do some choose a single vs. a double lung transplant? Cost? C_53_Familial IPF_5/09, Washington HOPE doesn't disappoint! To: Breathe-Support Sent: Tue, January 19, 2010 5:05:05 PMSubject: Steve Knipstein Just wanted to report that Steve is currently in surgery having a right single lung transplant at Brigham and Womens Hospital in Boston. Surgery started at about 6pm eastern time and will be about 6 hours. Will post any further info as I hear it. I know that Steve and his family will appreciate any prayers and loving thoughts sent their way! Beth Moderator Fibrotic NSIP 06/06 Dermatomyositis 11/08 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 20, 2010 Report Share Posted January 20, 2010 , To my knowledge cost of single vs double is not a deciding factor for a patient. As far as I know lung availability is the biggest deciding factor of the single vs double decision. There was a paper presented last year at the International Society for Heart Lung Transplantations meeting in Paris. In it survival data obtained from UNOS from 1987 through 1997. They compared folks who survived 10 years to folks who survived 1 to 5 years. Among the strongest factors in those who survived longer than 10 years was bilateral transplantation. In other words a double lung transplant. The other factors included things like close antigen matching and whether the recipient had a college education. Not all transplant centers do bilaterals some do them under limited circumstances. It is harder to get two lungs than single lungs. If I was dying and waiting for transplant and they offered me a single lung I might be tempted to take it rather than hanging out waiting for a matched set. It does appear however that double transplant is the optimum at least for some people. Some places (Duke is among them) do mostly doubles. Beth Moderator Fibrotic NSIP 06/06 Dermatomyositis 11/08 To: Breathe-Support Sent: Wed, January 20, 2010 9:05:46 PMSubject: Re: Steve Knipstein Why do some choose a single vs. a double lung transplant? Cost? C_53_Familial IPF_5/09, Washington HOPE doesn't disappoint! From: Beth <mbmurtha (AT) yahoo (DOT) com>To: Breathe-Support@ yahoogroups. comSent: Tue, January 19, 2010 5:05:05 PMSubject: Steve Knipstein Just wanted to report that Steve is currently in surgery having a right single lung transplant at Brigham and Womens Hospital in Boston. Surgery started at about 6pm eastern time and will be about 6 hours. Will post any further info as I hear it. I know that Steve and his family will appreciate any prayers and loving thoughts sent their way! Beth Moderator Fibrotic NSIP 06/06 Dermatomyositis 11/08 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 21, 2010 Report Share Posted January 21, 2010 cost has nothing to do with single vs double for many people with pf a single is fine, remember people can live with one healthy lung cancer patients frequently lose one lung or part of a lung and do fine other factors include in simplified terms: a shorter, less complicated surgery single lung transplants tend to do better than double lung transplants this is the way it was explained to me by both transplant doc and transplant surgeon on the other hand, someone with cystic fibrosis has to have a double lung transplant people with CF tend to be younger than people with PF [there are exceptions] the docs also look at total health of the individual, age, etc the remaining PF lung is just there Pink Joyce R (IPF 3/06) IFA 5/09 Pennsylvania Donate Life Listed 1/09 Inactive 4/09 www.transplantfund.org--- Subject: Re: Steve KnipsteinTo: Breathe-Support Date: Wednesday, January 20, 2010, 9:05 PM Why do some choose a single vs. a double lung transplant? Cost? C_53_Familial IPF_5/09, Washington HOPE doesn't disappoint! From: Beth <mbmurtha (AT) yahoo (DOT) com>To: Breathe-Support@ yahoogroups. comSent: Tue, January 19, 2010 5:05:05 PMSubject: Steve Knipstein Just wanted to report that Steve is currently in surgery having a right single lung transplant at Brigham and Womens Hospital in Boston. Surgery started at about 6pm eastern time and will be about 6 hours. Will post any further info as I hear it. I know that Steve and his family will appreciate any prayers and loving thoughts sent their way! Beth Moderator Fibrotic NSIP 06/06 Dermatomyositis 11/08 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 21, 2010 Report Share Posted January 21, 2010 mary beth that's interesting almost the opposite of what i was told Pink Joyce R (IPF 3/06) IFA 5/09 Pennsylvania Donate Life Listed 1/09 Inactive 4/09 www.transplantfund.org--- Subject: Re: Steve KnipsteinTo: Breathe-Support Date: Wednesday, January 20, 2010, 9:30 PM , To my knowledge cost of single vs double is not a deciding factor for a patient. As far as I know lung availability is the biggest deciding factor of the single vs double decision. There was a paper presented last year at the International Society for Heart Lung Transplantations meeting in Paris. In it survival data obtained from UNOS from 1987 through 1997. They compared folks who survived 10 years to folks who survived 1 to 5 years. Among the strongest factors in those who survived longer than 10 years was bilateral transplantation. In other words a double lung transplant. The other factors included things like close antigen matching and whether the recipient had a college education. Not all transplant centers do bilaterals some do them under limited circumstances. It is harder to get two lungs than single lungs. If I was dying and waiting for transplant and they offered me a single lung I might be tempted to take it rather than hanging out waiting for a matched set. It does appear however that double transplant is the optimum at least for some people. Some places (Duke is among them) do mostly doubles. Beth Moderator Fibrotic NSIP 06/06 Dermatomyositis 11/08 From: worth <hope2thend (AT) yahoo (DOT) com>To: Breathe-Support@ yahoogroups. comSent: Wed, January 20, 2010 9:05:46 PMSubject: Re: Steve Knipstein Why do some choose a single vs. a double lung transplant? Cost? C_53_Familial IPF_5/09, Washington HOPE doesn't disappoint! From: Beth <mbmurtha (AT) yahoo (DOT) com>To: Breathe-Support@ yahoogroups. comSent: Tue, January 19, 2010 5:05:05 PMSubject: Steve Knipstein Just wanted to report that Steve is currently in surgery having a right single lung transplant at Brigham and Womens Hospital in Boston. Surgery started at about 6pm eastern time and will be about 6 hours. Will post any further info as I hear it. I know that Steve and his family will appreciate any prayers and loving thoughts sent their way! Beth Moderator Fibrotic NSIP 06/06 Dermatomyositis 11/08 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 21, 2010 Report Share Posted January 21, 2010 Joyce, I can't speak to what you were told but the data shows that in general long term survival rates are better with bilateral lung transplant.That doesn't mean however that single lung transplant is not desireable and it doesn't mean that you can't have long term survival with a single lung transplant. It just means that over the ten year period, 87-97 those with bilateral transplants lived longer. However and this is a big however....we have to remember that lung transplant has come a long way even since 1997. Overall survival rates are higher and are improving. There are some instances where single lung transplant may be more desireable and availability of organs continues to be a major issue. If it was true that single lung transplant recipients always lived longer there'd never be any reason to do a bilateral transplant would there? Here is the text of the abstract in question. The full presentation is on the ISHLT website.(www.ishlt.org) [9] Factors Indicative of Long Term Survival after Lung Transplantation: A Review of 890 10-Year SurvivorsE.S. Weiss, J.G. , C.A. Merlo, J.V. Conte, A.S. Shah Division of Cardiac Surgery, Dept of Surgery, The s Hopkins University School of Medicine, Baltimore, MD; Division of Pulmonology and Critical Medicine, Dept of Medicine, The s Hopkins University of School of Medicine, Baltimore, MDPurpose: Despite 20 years of lung transplantation (LTx), factors influencing long term survival remain largely unknown. The United Network for Organ Sharing(UNOS) dataset provides an opportunity to examine long term LTx survivors.Methods and Materials: We conducted a case-control study embedded within the prospectively collected UNOS LTx cohort to identify 890 adults from 1987-1997, who survived ≥10 years after first LTx. Patients transplanted within the same era and surviving 1-5 yrs served as controls. Multivariable (MV) stepwise logistic regression with incorporation of interaction terms evaluated factors indicative of long term survival. To address LTx era, MV analysis was first performed on a randomly generated subset of cases (n=720) and independently validated comparing remaining patients (n=160) to additional controls transplanted from 1998-2002. Other outcomes evaluated included return to normal quality of life (QOL) and time to bronchiolitis obliterans (BO).Results: Of 5,111 LTx patients from 1987-1997, 890 (17%) survived ≥10 years (mean follow up (f/u) 12.2±1.7 yrs). Mean f/u for controls (N=1,657) was 2.8±1.1 yrs. The distribution of 10 yr survivors by disease was: cystic fibrosis (CF) 196 (22%), chronic obstructive pulmonary disease (COPD) 254 (29%) and idiopathic pulmonary fibrosis IPF 94 (11%). On MV logistic regression, significant factors indicative of 10 year survival included bilateral (BLT) vs. singe LTx (OR 2.45 [1.49-4.04], p<0.001), 5 or 6 HLA antigen match (OR 1.51 [1.02-2.22],p=0.04) and college education (OR 1.45 [1.01-2.02], p=0.05). After LTx, 10 year survivors had lower oxygen requirements (0.2 vs 1 L/min O2, p<0.001), fewer hospitalizations (0.5 vs. 0.6, p<0.001) and treatments (1.4 vs 1.6, p=0.01) for rejection, longer times to the development of BO (149 vs. 34 months, p<0.001) and were more likely to report normal QOL (38 vs. 8%,p<0.001).Conclusions: Examination of a cohort of long term LTx survivors in the UNOS dataset indicates that BLT, HLA matching, and higher education may portend improved survival following LTx.Wednesday, April 22, 2009 5:30 PM Beth Moderator Fibrotic NSIP 06/06 Dermatomyositis 11/08 To: Breathe-Support Sent: Thu, January 21, 2010 8:36:54 AMSubject: Re: Steve Knipstein mary beth that's interesting almost the opposite of what i was told Pink Joyce R (IPF 3/06) IFA 5/09 Pennsylvania Donate Life Listed 1/09 Inactive 4/09 www.transplantfund. org From: Beth <mbmurtha (AT) yahoo (DOT) com>Subject: Re: Steve KnipsteinTo: Breathe-Support@ yahoogroups. comDate: Wednesday, January 20, 2010, 9:30 PM , To my knowledge cost of single vs double is not a deciding factor for a patient. As far as I know lung availability is the biggest deciding factor of the single vs double decision. There was a paper presented last year at the International Society for Heart Lung Transplantations meeting in Paris. In it survival data obtained from UNOS from 1987 through 1997. They compared folks who survived 10 years to folks who survived 1 to 5 years. Among the strongest factors in those who survived longer than 10 years was bilateral transplantation. In other words a double lung transplant. The other factors included things like close antigen matching and whether the recipient had a college education. Not all transplant centers do bilaterals some do them under limited circumstances. It is harder to get two lungs than single lungs. If I was dying and waiting for transplant and they offered me a single lung I might be tempted to take it rather than hanging out waiting for a matched set. It does appear however that double transplant is the optimum at least for some people. Some places (Duke is among them) do mostly doubles. Beth Moderator Fibrotic NSIP 06/06 Dermatomyositis 11/08 From: worth <hope2thend (AT) yahoo (DOT) com>To: Breathe-Support@ yahoogroups. comSent: Wed, January 20, 2010 9:05:46 PMSubject: Re: Steve Knipstein Why do some choose a single vs. a double lung transplant? Cost? C_53_Familial IPF_5/09, Washington HOPE doesn't disappoint! From: Beth <mbmurtha (AT) yahoo (DOT) com>To: Breathe-Support@ yahoogroups. comSent: Tue, January 19, 2010 5:05:05 PMSubject: Steve Knipstein Just wanted to report that Steve is currently in surgery having a right single lung transplant at Brigham and Womens Hospital in Boston. Surgery started at about 6pm eastern time and will be about 6 hours. Will post any further info as I hear it. I know that Steve and his family will appreciate any prayers and loving thoughts sent their way! Beth Moderator Fibrotic NSIP 06/06 Dermatomyositis 11/08 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 21, 2010 Report Share Posted January 21, 2010 there are still reasons to do bilateral -- there are lots of varialbles wonder what the data from 97 to 2007 says Pink Joyce R (IPF 3/06) IFA 5/09 Pennsylvania Donate Life Listed 1/09 Inactive 4/09 www.transplantfund.org--- Subject: Re: Steve KnipsteinTo: Breathe-Support Date: Thursday, January 21, 2010, 10:09 AM Joyce, I can't speak to what you were told but the data shows that in general long term survival rates are better with bilateral lung transplant.That doesn't mean however that single lung transplant is not desireable and it doesn't mean that you can't have long term survival with a single lung transplant. It just means that over the ten year period, 87-97 those with bilateral transplants lived longer. However and this is a big however....we have to remember that lung transplant has come a long way even since 1997. Overall survival rates are higher and are improving. There are some instances where single lung transplant may be more desireable and availability of organs continues to be a major issue. If it was true that single lung transplant recipients always lived longer there'd never be any reason to do a bilateral transplant would there? Here is the text of the abstract in question. The full presentation is on the ISHLT website.(www.ishlt.org) [9] Factors Indicative of Long Term Survival after Lung Transplantation: A Review of 890 10-Year SurvivorsE.S. Weiss, J.G. , C.A. Merlo, J.V. Conte, A.S. Shah Division of Cardiac Surgery, Dept of Surgery, The s Hopkins University School of Medicine, Baltimore, MD; Division of Pulmonology and Critical Medicine, Dept of Medicine, The s Hopkins University of School of Medicine, Baltimore, MDPurpose: Despite 20 years of lung transplantation (LTx), factors influencing long term survival remain largely unknown. The United Network for Organ Sharing(UNOS) dataset provides an opportunity to examine long term LTx survivors.Methods and Materials: We conducted a case-control study embedded within the prospectively collected UNOS LTx cohort to identify 890 adults from 1987-1997, who survived ≥10 years after first LTx. Patients transplanted within the same era and surviving 1-5 yrs served as controls. Multivariable (MV) stepwise logistic regression with incorporation of interaction terms evaluated factors indicative of long term survival. To address LTx era, MV analysis was first performed on a randomly generated subset of cases (n=720) and independently validated comparing remaining patients (n=160) to additional controls transplanted from 1998-2002. Other outcomes evaluated included return to normal quality of life (QOL) and time to bronchiolitis obliterans (BO).Results: Of 5,111 LTx patients from 1987-1997, 890 (17%) survived ≥10 years (mean follow up (f/u) 12.2±1.7 yrs). Mean f/u for controls (N=1,657) was 2.8±1.1 yrs. The distribution of 10 yr survivors by disease was: cystic fibrosis (CF) 196 (22%), chronic obstructive pulmonary disease (COPD) 254 (29%) and idiopathic pulmonary fibrosis IPF 94 (11%). On MV logistic regression, significant factors indicative of 10 year survival included bilateral (BLT) vs. singe LTx (OR 2.45 [1.49-4.04], p<0.001), 5 or 6 HLA antigen match (OR 1.51 [1.02-2.22], p=0.04) and college education (OR 1.45 [1.01-2.02], p=0.05). After LTx, 10 year survivors had lower oxygen requirements (0.2 vs 1 L/min O2, p<0.001), fewer hospitalizations (0.5 vs. 0.6, p<0.001) and treatments (1.4 vs 1.6, p=0.01) for rejection, longer times to the development of BO (149 vs. 34 months, p<0.001) and were more likely to report normal QOL (38 vs. 8%,p<0.001).Conclusions: Examination of a cohort of long term LTx survivors in the UNOS dataset indicates that BLT, HLA matching, and higher education may portend improved survival following LTx.Wednesday, April 22, 2009 5:30 PM Beth Moderator Fibrotic NSIP 06/06 Dermatomyositis 11/08 From: Joyce T Rosenberg <pinkrockybeach@ yahoo.com>To: Breathe-Support@ yahoogroups. comSent: Thu, January 21, 2010 8:36:54 AMSubject: Re: Steve Knipstein mary beth that's interesting almost the opposite of what i was told Pink Joyce R (IPF 3/06) IFA 5/09 Pennsylvania Donate Life Listed 1/09 Inactive 4/09 www.transplantfund. org From: Beth <mbmurtha (AT) yahoo (DOT) com>Subject: Re: Steve KnipsteinTo: Breathe-Support@ yahoogroups. comDate: Wednesday, January 20, 2010, 9:30 PM , To my knowledge cost of single vs double is not a deciding factor for a patient. As far as I know lung availability is the biggest deciding factor of the single vs double decision. There was a paper presented last year at the International Society for Heart Lung Transplantations meeting in Paris. In it survival data obtained from UNOS from 1987 through 1997. They compared folks who survived 10 years to folks who survived 1 to 5 years. Among the strongest factors in those who survived longer than 10 years was bilateral transplantation. In other words a double lung transplant. The other factors included things like close antigen matching and whether the recipient had a college education. Not all transplant centers do bilaterals some do them under limited circumstances. It is harder to get two lungs than single lungs. If I was dying and waiting for transplant and they offered me a single lung I might be tempted to take it rather than hanging out waiting for a matched set. It does appear however that double transplant is the optimum at least for some people. Some places (Duke is among them) do mostly doubles. Beth Moderator Fibrotic NSIP 06/06 Dermatomyositis 11/08 From: worth <hope2thend (AT) yahoo (DOT) com>To: Breathe-Support@ yahoogroups. comSent: Wed, January 20, 2010 9:05:46 PMSubject: Re: Steve Knipstein Why do some choose a single vs. a double lung transplant? Cost? C_53_Familial IPF_5/09, Washington HOPE doesn't disappoint! From: Beth <mbmurtha (AT) yahoo (DOT) com>To: Breathe-Support@ yahoogroups. comSent: Tue, January 19, 2010 5:05:05 PMSubject: Steve Knipstein Just wanted to report that Steve is currently in surgery having a right single lung transplant at Brigham and Womens Hospital in Boston. Surgery started at about 6pm eastern time and will be about 6 hours. Will post any further info as I hear it. I know that Steve and his family will appreciate any prayers and loving thoughts sent their way! Beth Moderator Fibrotic NSIP 06/06 Dermatomyositis 11/08 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 21, 2010 Report Share Posted January 21, 2010 Joyce, I don't know that anyone has looked at that data in the same way. They may have, I just haven't seen it. You are correct there are many variables. I just happen to be a patient at a center (Duke) that strongly favors bilateral (double) transplant over single in patients with our type of lung disease. Transplant candidates at Duke with pulmonary fibrosis or cystic fibrosis almost always have bilateral transplants. Those candidates at Duke with other types of respiratory illness such as COPD or asthma often have single lung transplants. Beth Moderator Fibrotic NSIP 06/06 Dermatomyositis 11/08 To: Breathe-Support Sent: Thu, January 21, 2010 10:16:11 AMSubject: Re: Steve Knipstein there are still reasons to do bilateral -- there are lots of varialbles wonder what the data from 97 to 2007 says Pink Joyce R (IPF 3/06) IFA 5/09 Pennsylvania Donate Life Listed 1/09 Inactive 4/09 www.transplantfund. org From: Beth <mbmurtha (AT) yahoo (DOT) com>Subject: Re: Steve KnipsteinTo: Breathe-Support@ yahoogroups. comDate: Wednesday, January 20, 2010, 9:30 PM , To my knowledge cost of single vs double is not a deciding factor for a patient. As far as I know lung availability is the biggest deciding factor of the single vs double decision. There was a paper presented last year at the International Society for Heart Lung Transplantations meeting in Paris. In it survival data obtained from UNOS from 1987 through 1997. They compared folks who survived 10 years to folks who survived 1 to 5 years. Among the strongest factors in those who survived longer than 10 years was bilateral transplantation. In other words a double lung transplant. The other factors included things like close antigen matching and whether the recipient had a college education. Not all transplant centers do bilaterals some do them under limited circumstances. It is harder to get two lungs than single lungs. If I was dying and waiting for transplant and they offered me a single lung I might be tempted to take it rather than hanging out waiting for a matched set. It does appear however that double transplant is the optimum at least for some people. Some places (Duke is among them) do mostly doubles. Beth Moderator Fibrotic NSIP 06/06 Dermatomyositis 11/08 From: worth <hope2thend (AT) yahoo (DOT) com>To: Breathe-Support@ yahoogroups. comSent: Wed, January 20, 2010 9:05:46 PMSubject: Re: Steve Knipstein Why do some choose a single vs. a double lung transplant? Cost? C_53_Familial IPF_5/09, Washington HOPE doesn't disappoint! From: Beth <mbmurtha (AT) yahoo (DOT) com>To: Breathe-Support@ yahoogroups. comSent: Tue, January 19, 2010 5:05:05 PMSubject: Steve Knipstein Just wanted to report that Steve is currently in surgery having a right single lung transplant at Brigham and Womens Hospital in Boston. Surgery started at about 6pm eastern time and will be about 6 hours. Will post any further info as I hear it. I know that Steve and his family will appreciate any prayers and loving thoughts sent their way! Beth Moderator Fibrotic NSIP 06/06 Dermatomyositis 11/08 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 21, 2010 Report Share Posted January 21, 2010 As I understood it, and I may be wrong, if there are no other recipiants with the same match then one person could get both lungs? Ken O. To: Breathe-Support Sent: Wed, January 20, 2010 6:30:38 PMSubject: Re: Steve Knipstein , To my knowledge cost of single vs double is not a deciding factor for a patient. As far as I know lung availability is the biggest deciding factor of the single vs double decision. There was a paper presented last year at the International Society for Heart Lung Transplantations meeting in Paris. In it survival data obtained from UNOS from 1987 through 1997. They compared folks who survived 10 years to folks who survived 1 to 5 years. Among the strongest factors in those who survived longer than 10 years was bilateral transplantation. In other words a double lung transplant. The other factors included things like close antigen matching and whether the recipient had a college education. Not all transplant centers do bilaterals some do them under limited circumstances.. It is harder to get two lungs than single lungs. If I was dying and waiting for transplant and they offered me a single lung I might be tempted to take it rather than hanging out waiting for a matched set. It does appear however that double transplant is the optimum at least for some people. Some places (Duke is among them) do mostly doubles.. Beth Moderator Fibrotic NSIP 06/06 Dermatomyositis 11/08 From: worth <hope2thend (AT) yahoo (DOT) com>To: Breathe-Support@ yahoogroups. comSent: Wed, January 20, 2010 9:05:46 PMSubject: Re: Steve Knipstein Why do some choose a single vs. a double lung transplant? Cost? C_53_Familial IPF_5/09, Washington HOPE doesn't disappoint! From: Beth <mbmurtha (AT) yahoo (DOT) . com>To: Breathe-Support@ yahoogroups. comSent: Tue, January 19, 2010 5:05:05 PMSubject: Steve Knipstein Just wanted to report that Steve is currently in surgery having a right single lung transplant at Brigham and Womens Hospital in Boston. Surgery started at about 6pm eastern time and will be about 6 hours. Will post any further info as I hear it. I know that Steve and his family will appreciate any prayers and loving thoughts sent their way! Beth Moderator Fibrotic NSIP 06/06 Dermatomyositis 11/08 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 21, 2010 Report Share Posted January 21, 2010 Ken There are many factors. Sometimes too, one of the lungs isn't good or was even damaged in the accident. From everyone I've talked to they would love two lungs in most cases but they'd also like to do as many patients as possible. On younger patients though they work very hard to get two lungs as they are anticipated needing them much longer. They are still learning too. They have no idea what the maximum life is with transplanted lungs or if there is any normal limit. There's a small group of people and I have no idea how many who have had the second transplant. Compared to other things, lung tranplants are so relatively new and I anticipate the improvements we're seeing now and will see in the next few years will be incredible. There is a very simple premise in play, " The More We Do, The Better We Get. " > > As I understood it, and I may be wrong, if there are no other recipiants with the same match then one person could get both lungs? >  > Ken O. > > > > > ________________________________ > From: Beth mbmurtha@... > To: Breathe-Support > Sent: Wed, January 20, 2010 6:30:38 PM > Subject: Re: Steve Knipstein > >  > , > To my knowledge cost of single vs double is not a deciding factor for a patient. As far as I know lung availability is the biggest deciding factor of the single vs double decision. > > There was a paper presented last year at the International Society for Heart Lung Transplantations meeting in Paris. In it survival data obtained from UNOS from 1987 through 1997. They compared folks who survived 10 years to folks who survived 1 to 5 years. Among the strongest factors in those who survived longer than 10 years was bilateral transplantation. In other words a double lung transplant. The other factors included things like close antigen matching and whether the recipient had a college education. Not all transplant centers do bilaterals some do them under limited circumstances. It is harder to get two lungs than single lungs. If I was dying and waiting for transplant and they offered me a single lung I might be tempted to take it rather than hanging out waiting for a matched set. > It does appear however that double transplant is the optimum at least for some people. Some places (Duke is among them) do mostly doubles. > > >  > Beth > Moderator > Fibrotic NSIP 06/06 Dermatomyositis 11/08 >  >  > > > > > ________________________________ > From: worth hope2thend (AT) yahoo (DOT) com> > To: Breathe-Support@ yahoogroups. com > Sent: Wed, January 20, 2010 9:05:46 PM > Subject: Re: Steve Knipstein > >  > Why do some choose a single vs. a double lung transplant? Cost? >  > C_53_Familial IPF_5/09, Washington > HOPE doesn't disappoint! > > > > > > ________________________________ > From: Beth mbmurtha (AT) yahoo (DOT) com> > To: Breathe-Support@ yahoogroups. com > Sent: Tue, January 19, 2010 5:05:05 PM > Subject: Steve Knipstein > >  > Just wanted to report that Steve is currently in surgery having a right single lung transplant at Brigham and Womens Hospital in Boston. Surgery started at about 6pm eastern time and will be about 6 hours. > Will post any further info as I hear it. I know that Steve and his family will appreciate any prayers and loving thoughts sent their way! >  > Beth > Moderator > Fibrotic NSIP 06/06 Dermatomyositis 11/08 >  >  > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 21, 2010 Report Share Posted January 21, 2010 good to know, thanks! C_53_Familial IPF_5/09, Washington HOPE doesn't disappoint! To: Breathe-Support@...Sent: Thu, January 21, 2010 5:34:00 AMSubject: Re: Steve Knipstein cost has nothing to do with single vs double for many people with pf a single is fine, remember people can live with one healthy lung cancer patients frequently lose one lung or part of a lung and do fine other factors include in simplified terms: a shorter, less complicated surgery single lung transplants tend to do better than double lung transplants this is the way it was explained to me by both transplant doc and transplant surgeon on the other hand, someone with cystic fibrosis has to have a double lung transplant people with CF tend to be younger than people with PF [there are exceptions] the docs also look at total health of the individual, age, etc the remaining PF lung is just there Pink Joyce R (IPF 3/06) IFA 5/09 Pennsylvania Donate Life Listed 1/09 Inactive 4/09 www.transplantfund. org From: worth <hope2thend (AT) yahoo (DOT) com>Subject: Re: Steve KnipsteinTo: Breathe-Support@ yahoogroups. comDate: Wednesday, January 20, 2010, 9:05 PM Why do some choose a single vs. a double lung transplant? Cost? C_53_Familial IPF_5/09, Washington HOPE doesn't disappoint! From: Beth <mbmurtha (AT) yahoo (DOT) com>To: Breathe-Support@ yahoogroups. comSent: Tue, January 19, 2010 5:05:05 PMSubject: Steve Knipstein Just wanted to report that Steve is currently in surgery having a right single lung transplant at Brigham and Womens Hospital in Boston. Surgery started at about 6pm eastern time and will be about 6 hours. Will post any further info as I hear it. I know that Steve and his family will appreciate any prayers and loving thoughts sent their way! Beth Moderator Fibrotic NSIP 06/06 Dermatomyositis 11/08 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 22, 2010 Report Share Posted January 22, 2010 yes that is what i was told last year when i met with the surgeon Pink Joyce R (IPF 3/06) IFA 5/09 Pennsylvania Donate Life Listed 1/09 Inactive 4/09 www.transplantfund.org--- Subject: Re: Steve KnipsteinTo: Breathe-Support Date: Thursday, January 21, 2010, 12:31 PM As I understood it, and I may be wrong, if there are no other recipiants with the same match then one person could get both lungs? Ken O. From: Beth <mbmurtha (AT) yahoo (DOT) com>To: Breathe-Support@ yahoogroups. comSent: Wed, January 20, 2010 6:30:38 PMSubject: Re: Steve Knipstein , To my knowledge cost of single vs double is not a deciding factor for a patient. As far as I know lung availability is the biggest deciding factor of the single vs double decision. There was a paper presented last year at the International Society for Heart Lung Transplantations meeting in Paris. In it survival data obtained from UNOS from 1987 through 1997. They compared folks who survived 10 years to folks who survived 1 to 5 years. Among the strongest factors in those who survived longer than 10 years was bilateral transplantation. In other words a double lung transplant. The other factors included things like close antigen matching and whether the recipient had a college education. Not all transplant centers do bilaterals some do them under limited circumstances. . It is harder to get two lungs than single lungs. If I was dying and waiting for transplant and they offered me a single lung I might be tempted to take it rather than hanging out waiting for a matched set. It does appear however that double transplant is the optimum at least for some people. Some places (Duke is among them) do mostly doubles.. Beth Moderator Fibrotic NSIP 06/06 Dermatomyositis 11/08 From: worth <hope2thend (AT) yahoo (DOT) com>To: Breathe-Support@ yahoogroups. comSent: Wed, January 20, 2010 9:05:46 PMSubject: Re: Steve Knipstein Why do some choose a single vs. a double lung transplant? Cost? C_53_Familial IPF_5/09, Washington HOPE doesn't disappoint! From: Beth <mbmurtha (AT) yahoo (DOT) . com>To: Breathe-Support@ yahoogroups. comSent: Tue, January 19, 2010 5:05:05 PMSubject: Steve Knipstein Just wanted to report that Steve is currently in surgery having a right single lung transplant at Brigham and Womens Hospital in Boston. Surgery started at about 6pm eastern time and will be about 6 hours. Will post any further info as I hear it. I know that Steve and his family will appreciate any prayers and loving thoughts sent their way! Beth Moderator Fibrotic NSIP 06/06 Dermatomyositis 11/08 Quote Link to comment Share on other sites More sharing options...
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