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Hi All;

My son and I are also the only ones in our family with CMT. As far as my

Father and his family, we are unsure. We have not heard nor seen him for

over 13 years. At first my friends would ask me, why I don't look him up

and investigate his family's history. My reply was if it would cure or help

us in any way; I would. With this disease, I believe the present and

future is what is important.

Lee

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Hi it's me Carolyn Iam back and i would really like to

have genetic testing done except the findings may go

against for future insurances. is being fitted

with his ankle supports on tuesday he is thrilled[not]

-take care CAROLYN-- Gretchen Glick <liliwigg@...>

wrote:

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I am the only person in my family, anywhere, past and

present who has<BR>

CMT. I was diagnosed along time ago before genetic

testing and my docs<BR>

think it is pointless now. And that is OK with me. ~

G<BR>

</tt>

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  • 3 years later...

Hi Liz,

I'm not sure about whether you can or not get

genetic testing in Australia. However, Dr

Shelling in Auckland is carrying out BPES genetic

testing.

a.shelling@...

All the best,

--- lizzy72mal <lizzy72mal@...> wrote:

>

>

> Hi,

>

> My son and husband have BPES and we live in

> Australia. I understand

> that genetic testing to determine if they have

> Type 1 or 2 is

> available in New Zealand but not in Australia.

> Could someone

> possibly give me the contact details where the

> genetic testing can

> be undertaken in New Zealand.

>

> Thanks.

>

> Liz

>

>

>

>

>

>

>

Find local movie times and trailers on Movies.

http://au.movies.

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I have BPES and so does my two month old daughter and my father. What are the benefits of getting genetic testing?

thank you

Beth Fairbairn <andreajoyf@...> wrote:

Hi Liz,I'm not sure about whether you can or not getgenetic testing in Australia. However, Dr Shelling in Auckland is carrying out BPES genetictesting.a.shelling@...All the best, --- lizzy72mal <lizzy72mal@...> wrote: > > > Hi,> > My son and husband have BPES and we live in> Australia. I understand > that genetic testing to determine if they have> Type 1 or 2 is > available in New Zealand but not in Australia. > Could someone > possibly give me the contact details where the> genetic testing can > be undertaken in New Zealand.> > Thanks.> > Liz> > > > > > > Find local movie times and trailers on

Movies.http://au.movies.

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Hello Liz,

welcome to rhe group. We live in NZ & there is a Dr Komudi

Siriwardena in Auckland who is the geneticist that my daughter

, aged 18yrs, will see in a few weeks time. Her & I are the

only ones in our family with BPES. Its good to have as much

information as you can before going to the geneticist, regarding

other family members who are affected eg. aunts, uncles, grandies etc.

Now, I`m not sure what part of Oz you are, but there is a Dr

Mackey at the Eye & Ear Hospital in Melbourne & a Dr Craig in

Adelaide who could help point you in the right direction.

Hope this is helpful

Keep in touch

Maree

-- In blepharophimosis , " lizzy72mal "

<lizzy72mal@y...> wrote:

>

>

> Hi,

>

> My son and husband have BPES and we live in Australia. I

understand

> that genetic testing to determine if they have Type 1 or 2 is

> available in New Zealand but not in Australia. Could someone

> possibly give me the contact details where the genetic testing can

> be undertaken in New Zealand.

>

> Thanks.

>

> Liz

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  • 3 months later...

My husband Jim just got his results from the Athena testing: PMP22

duplication/deletion " inconclusive. " The 9 sequencing tests were all " no

sequence

alteration " or negative. Has anyone else had an inconclusive test? Did

repeating the test change the result? It won't make any difference to him, but

one

of our sons is considering starting a family. Five or so years ago he had at

test for one or two genes when we were going to MDA at UCLA [we now go to

Santa Barbara], but I don't know which gene(s), and we were told the tests were

negative.

Elinor

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Elinor,

I had DNA tests done through Athena. Only results was that it wasn't CIDP.

After spinal tap, doctor said it is CMT 2 and that the only thing they can do is

help me manage it. Meanwhile, I'm exercising regularly and using nutritional

products. I've had three different diagnoses from three different doctors. I'm

thinking about seeing another doctor SO I can get ANOTHER diagnosis. <grin>

Frustrating, isn't it?

Carl

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I know how you feel! My blood test did not show anything also and now they are

thinking mine is SMA after 20 years being told CMT. I guess that is what

technology does (LOL)

Jackie

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  • 4 weeks later...

Beth,

I'm not sure about your question about the testing, but give you my opinion based on my experience with BPES as far as having another child with BPES. My grandfather has BPES and his first son, my father, had it as well. His second son did not have it. I am was the first born in my family and i have, but my brother doesn't. My first born has it, but my 2nd doesn't, and my 3rd has it. I just know that there is a 50/50 chance of passing it down. It surely didn't interfere with my decisions to have children though. No matter if they had it or not i knew i wanted more than one child.

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Thank you for your message, I know I want another child but

probably right now it is too soon for me to really make a decision,

we are in the middle of too much stress. We had an unusually

difficult time with Lily's surgeries due to the infection she got, I

look at her now and I think if the surgery had been successful the

first time, she would have been fine and we wouldn't have gone

through so much pain for her first six months, but for whatever

reason, it turned out that way. What matters now is that she can see

everything and she is such a wonderful little baby.

I admire you for not being as afraid as I am. You probably don't

think it's any big deal but to me your are brave.

thank you again

Beth

>

> Beth,

>

> I'm not sure about your question about the testing, but give you

my opinion based on my experience with BPES as far as having another

child with BPES. My grandfather has BPES and his first son, my

father, had it as well. His second son did not have it. I am was

the first born in my family and i have, but my brother doesn't. My

first born has it, but my 2nd doesn't, and my 3rd has it. I just

know that there is a 50/50 chance of passing it down. It surely

didn't interfere with my decisions to have children though. No

matter if they had it or not i knew i wanted more than one child.

>

>

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Hi

I dont know past my Father in Law ..but he had it, my husbands oldest brother and sister do not ...my husband the last has it, my two sons have it ...and I am Due June 9th with #3 a little girl!!!!!! praying she does not...but it is a 50/50 chance...I dont think dealing with this has been extremly difficult for us. We have a great team of doctors and surgeons and my kids have no other problems at all. I look at it this way ....so many kids have something worse...maybe I am just trying to make myself feel bett, . I don;t know . I knew we wanted another and would deal with what God has in store for us...and i am not a very religios person either. But it is out of my hands.

Sharon

Feichtner <mfeichtner@...> wrote:

Beth,

I'm not sure about your question about the testing, but give you my opinion based on my experience with BPES as far as having another child with BPES. My grandfather has BPES and his first son, my father, had it as well. His second son did not have it. I am was the first born in my family and i have, but my brother doesn't. My first born has it, but my 2nd doesn't, and my 3rd has it. I just know that there is a 50/50 chance of passing it down. It surely didn't interfere with my decisions to have children though. No matter if they had it or not i knew i wanted more than one child.

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  • 1 year later...
Guest guest

I wanted to add something regarding IVF - preimplantation diagnosis

is different than a standard screening done during IVF. This is how

it would work in someone who either has BPES or whose spouse has it.

The spouse would be tested, If the mutation is located, then during

the IVF process, before implantation, cells are removed and tested

for THAT SAME MUTATION FOUND IN THE SPOUSE. I asked Dr. Rosenbaum if

anyone else with BPES that he sees, has used this technology. He said

no, not yet, but other families with other types of genetic disorders

are doing it. It's only been recently it was offered. He said it's

not 100% that the mutation can be found for BPES, which I think

people on this board have already covered.

I am not advocating this procedure, but I want to explain it so if

you are considering this, you know what to ask for. Just because

someone hasn't done it before doesn't mean it can't be done, you just

have to find the right people and ask the right questions. I have

learned this the hard way.... There were so many things I didn't know

about BPES, so much my parents didn't know. It's not such a bad thing

to know what the options are and make choices.

> >

> > Hi to everyone,

> > My appointment was interesting yesterday. I was very surprised

> > about the level of knowledge the doctor had about BPES. Although,

> > she advised the best way to discover whether POF is prevalent

would

> > be via fertility specialists and not through discovering whether

> > type 1 or 2 BPES. I thought this would be conclusive but

> apparently

> > not. I asked about screening of embryos through IVF but this is

> not

> > an option yet and she thinks this will not be available for

another

> > 40 years, only life limiting sydromes are screened for. The

doctor

> > mentioned about pre-natal screening but I was horrified to hear

> this

> > advice. My view is that if you are going through IVF and embryos

> > are screened that's one thing but to have a pre-natal to make

this

> > choice is a whole different decision which I don't believe should

> be

> > offered.

> >

> > The doctor took some blood anyway but no genetic testing for type

1

> > or 2 is available in the UK and needs to be sent to france or

> > belgium and I was advised results can take up to a year so I will

> > definately be concentrating on fertility advice and not holding

out

> > for the genetic results. If I am able to have a child I would

like

> > this result as whatever type I am, I understand my child will

be.

> >

> > so the uncertain time for me continues but I will continue

reading

> > the facinating discussions which is a strength to me at this

time.

> > Thankyou to those who posted kind words and those involved in

> > discussions. I think I may have started quite a healthy

> > discussion.

> >

> > To Bryony (new member) I can emphasize with you, some feelings

> about

> > POF which I am not sure whether I am at risk from POF or not. I

> > have experienced hot flushes but I have also recently come off

the

> > pill and unsure whether this is a hormonal side effect to this

but

> I

> > am very hypersensitive to everything at present. I hope you find

> > this site of use to you as I certainly so. Take care, D

> >

>

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  • 2 years later...
Guest guest

After following the thread about diagnosis, I thought I'd mention that I found a lab in Denver, CO which does cheek swab testing, Kimball Genetics. Here's the link to their celiac gene test: http://www.kimballgenetics.com/tests-celiacdisease.html. It includes an explanation of the genes under test. I called them and they sent me 2 test kids free of charge, and gave me the codes used for insurance purposes so we could check (our plan does cover them, it turns out). They quoted me $395 if they were to bill our insurance directly, or 10% less if we pay them directly and then submit for insurance ourselves. This is a much better price than I had expected, and our gastro was also surprised at the low price.

Have any of you used this lab?

Just FYI (but probably you all know already), this test will only tell you if you are susceptible to CD, not whether you actually have it. In our case, we want to know for our younger daughter who currently does not have CD. If she's not carrying one of those gene alleles, then we can stop testing her blood in the future. If we don't get gene information for her then our gastro recommends that she get a blood test about every 2 years or whenever she displays symptoms. And of course if she has the genes, then she'll still need regular blood tests anyway, but there's about a 50% chance she doesn't have them. My husband and I are also interested for ourselves, since it's highly likely that one of us carries the genes (there aren't many spontaneous gene mutations in these gene locations, so our daughter almost certainly inherited them from one of us), although neither of us currently has CD either. Only our 9-yr old daughter does, and she's a text-book case (off the charts blood test followed by a highly definitive biopsy of the duodenum.).

Best,

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