RE: Probiotics and CD discussed at recent Kaiser patient group meeting

[Guest guest]

Or grow your own by making kefir.

See the group kefir_making and get some kefir grains. Raise them in

good milk and use them to make kefired cider (if you are casein intolerant)

And make and eat your own raw sauerkraut

and lacto-fermented cucumber pickles.

None of this is hard, all of it is traditional

and all of it will help your tummy.

Connie

From: [mailto: ] On Behalf Of j. hogle

Sent: Sunday, June 08, 2008 3:03

PM

Subject: [ ]

Probiotics and CD discussed at recent Kaiser patient group meeting

At the recent celiac meeting at Kaiser Santa Clara, Dr.

Wong, a pediatric gastroenterologist at the clinic there discussed

probiotics and CD. He said that a number of rigorous scientific studies are

mostly in vitro rather than in vivo but that their results generally show that

probiotics can inhibit or, even, stop gliadin-caused damage. (I gave him

a couple of recent abstracts of such that he hadn't seen that also argue well

for probiotics likely value in humans.*) He also noted that the anecdotal

evidence is pretty good. Consequently, he does recommend to a number of

his patients that they take probiotic complexes that contain a greater variety

and tens of billions of bacteria as a dietary supplement. He gave a

couple of examples, including VSL#3.

Those who already use such products as VSL#3, Ultimate Flora, Flora Q, and

Florastor know that they are relatively expensive and non-prescription (I

checked with our Kaiser pharmacy). I have also not researched yet whether

it is a good idea to go from no added bacteria beyond that in yogurt to

something like VSL#3, which claims 450 billion total of eight different

bacteria). Trader Joe's does offer a starting point in its Trader

Darwin's Acidophilus & Probiotic Complex, which contains " 4 billion

organisms (at time of manufacture) "

consisting of Lactobacillus acidophilus, Lactobacillus helveticus,

Bifidobacterium bifidum and Streptococcus thermophilus. It is $5.99 for

50 tablets taken two at a time.

Hogle

Freelance academic librarian

Instructor, online research

Email: jjhogle

Web: www.blueroom.com

Reality ain't what you think it is

Art Graphics & Photographs

[http://www.blueroom.com/realityaint.htm]

* The following is the Title and

Abstract of a study just out in the June 2008 Clinical and Experimental

Immunology (pp 552-8):

Live probiotic Bifidobacterium lactis

bacteria inhibit the toxic effects induced by wheat gliadin in epithelial cell

culture.

Wheat gliadin induces severe intestinal symptoms and small-bowel mucosal

damage in coeliac disease patients. At present, the only effective treatment

for the disease is a strict life-long gluten-free diet. In this study we

investigated whether probiotics Lactobacillus

fermentum or Bifidobacterium

lactis can inhibit the toxic effects of gliadin in intestinal cell

culture conditions. The ability of live probiotics to inhibit peptic-tryptic

digested gliadin-induced damage to human colon cells Caco-2 was evaluated by

measuring epithelial permeability by transepithelial resistance, actin

cytoskeleton arrangements by the extent of membrane ruffling and expression of

tight junctional protein ZO-1. B. lactis inhibited the gliadin-induced increase

dose-dependently in epithelial permeability, higher concentrations completely

abolishing the gliadin-induced decrease in transepithelial resistance. The same

bacterial strain also inhibited the formation of membrane ruffles in Caco-2

cells induced by gliadin administration. Furthermore, it also protected the

tight junctions of Caco-2 cells against the effects of gliadin, as evinced by

the pattern of ZO-1 expression. We conclude

thus that live B. lactis bacteria can counteract directly the harmful effects

exerted by coeliac-toxic gliadin and would clearly warrant further studies of

its potential as a novel dietary supplement in the treatment of coeliac disease.

[Guest guest]

Its so good to see confirmation and dissemination of this knowledge at Kaiser!Question I have, when we eat cultured foods do the pro-biotic bacteria survive the stomach or not and get to the gut in sufficient numbers?BeaFrom: Connie Hampton <connie@...>Subject: RE: [ ] Probiotics and CD discussed at recent Kaiser patient group meeting Date: Sunday, June 8, 2008, 9:42 PM

Or grow your own by making kefir.

See the group kefir_making and get some kefir grains. Raise them in

good milk and use them to make kefired cider (if you are casein intolerant) And make and eat your own raw sauerkraut

and lacto-fermented cucumber pickles. None of this is hard, all of it is traditional

and all of it will help your tummy.

Connie

From: [mailto: ] On Behalf Of j. hogle

Sent: Sunday, June 08, 2008 3:03

PM

Subject: [ ]

Probiotics and CD discussed at recent Kaiser patient group meeting

At the recent celiac meeting at Kaiser Santa Clara, Dr.

Wong, a pediatric gastroenterologist at the clinic there discussed

probiotics and CD. He said that a number of rigorous scientific studies are

mostly in vitro rather than in vivo but that their results generally show that

probiotics can inhibit or, even, stop gliadin-caused damage.

[Guest guest]

Probiotics are acid-loving bacteria that

do survive the stomach, but don’t stay long in the (more neutral or even

base ph) gut so need to be replenished every day.

Connie

From: [mailto: ] On Behalf Of Beatrice Garth

Sent: Sunday, June 08, 2008 9:59

PM

Subject: RE: [ ]

Probiotics and CD discussed at recent Kaiser patient group meeting

Its so good to see

confirmation and dissemination of this knowledge at Kaiser!

Question I have, when we eat cultured foods do the pro-biotic bacteria survive

the stomach or not and get to the gut in sufficient numbers?

Bea

--- On Sun, 6/8/08, Connie Hampton <conniehampton-research>

wrote:

From:

Connie Hampton <conniehampton-research>

Subject: RE: [ ] Probiotics and CD discussed at recent Kaiser

patient group meeting

Date: Sunday, June 8, 2008, 9:42 PM

Or grow your own by making kefir. See the group

kefir_making and get some kefir grains. Raise them in good milk and use

them to make kefired cider (if you are casein intolerant)

And make and eat your own raw sauerkraut and lacto-fermented

cucumber pickles.

None of this is hard, all of it is traditional and all of it will

help your tummy.

Connie

From: [mailto: @

groups. com ] On Behalf Of j.

hogle

Sent: Sunday, June 08, 2008 3:03

PM

@ groups.

com

Subject: [ ]

Probiotics and CD discussed at recent Kaiser patient group meeting

At the recent celiac meeting at Kaiser Santa Clara,

Dr. Wong, a pediatric gastroenterologist at the clinic there

discussed probiotics and CD. He said that a number of rigorous scientific

studies are mostly in vitro rather than in vivo but that their results

generally show that probiotics can inhibit or, even, stop gliadin-caused

damage.

[Guest guest]

Thanks Connie! I still take the probiotics however as well as eat my live organic yogurt since it seems to help especially against a fungal infection I got as a result of too many antibiotics. I seem to be allergic to other forms of fermented things however than yogurt, but maybe the saurkraut would work.BeaFrom: Connie Hampton <connie@...>Subject: RE: [ ] Probiotics and CD discussed at recent Kaiser patient group meeting Date: Monday, June

9, 2008, 6:48 AM

Probiotics are acid-loving bacteria that

do survive the stomach, but don¢t stay long in the (more neutral or even

base ph) gut so need to be replenished every day.

Connie

From: [mailto: ] On Behalf Of Beatrice Garth

Sent: Sunday, June 08, 2008 9:59

PM

Subject: RE: [ ]

Probiotics and CD discussed at recent Kaiser patient group meeting

..