Tylenol (Acetaminophen) depletes Glutathione (necessary for removal of mercury)

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Tylenol (Acetaminophen) depletes Glutathione (necessary for removal of mercury)

http://www.whale.to/vaccine/tylenol_depletes_glutathione.html

 

 

http://www.wellness.com/blogs/DrMarkham/51/what-every-user-of-acetaminophen\

-needs-to-know/dr-laura-markham

" The danger is that there isn't much difference between a safe, effective

dose, and a toxic dose. Just a doubling of the maximum daily dose can be

enough to kill, warns Dr. Anne Larson of the University of Washington

Medical Center. The other problem is that if you have no food in your

stomach, or if you have alcohol in your system, or worse yet, both, (not

relevant for your kids unless they're teenagers, but think about that

tylenol you took for your hangover last month), the regular dosage can be

toxic because of the overload to the liver. "

COMMENT

" Glutathione is found in every one of the trillions of cells in the body.

It is most abundant in the liver and then the kidneys. These are the

detoxifying organs. NAC N-acetyl cystiene is provided to patients in every

hospital emergency situation in the USA for acetaminophen overdose. However

NAC has many side effects to the health of the individual, but the

alternative is certain death. So it is only administered in emergency room

situations. "

http://www.mercola.com/2005/may/17/tylenol_risk.htm

" Most experts believe Tylenol causes its damage by depleting glutathione.

If you keep your glutathione levels up, the damage from the Tylenol may be

largely preventable. Even conventional medicine recognizes this, as anyone

who overdoses on Tylenol receives large doses of NAC in the emergency room. "

http://www.sciencedaily.com/releases/2002/10/021014072451.htm

" An overdose of acetaminophen can cause depletion of glutathione and land a

person in the hospital. " Acetaminophen toxicity is the number one cause of

hospital admission for liver failure in the United States, " he said. "

http://www.benbest.com/nutrceut/NAC.html

" Glutathione detoxifies acetaminophen, but once glutathione is depleted

there can be significant cell death in the liver [THE AMERICAN JOURNAL OF

MEDICINE; Flanagan,RJ; 91(Suppl C):131S-139S (1991)]. AIDS victims can

suffer severe liver and kidney damage by using acetaminophen or alcohol,

which severely deplete glutatione [PROCEEDINGS OF THE NATIONAL ACADEMY OF

SCIENCES (USA); Herzenberg,LA; 94(5):1967-1972 (1997)]. "

http://www.ssafood.com/site/docsTopicsTips/Nourish%20Your%20Eyes.mht

" Glutathione, another antioxidant, also prevents cataracts. In fact, lenses

with cataracts contain one-fifteenth (1/15th) of the normal amount of

glutathione and one-tenth (1/10th) the normal level of vitamin C.

Glutathione is in asparagus, avocado, broccoli, garlic, onions, spinach,

tomatoes, watermelon, eggs and walnuts. Abel advises taking alpha lipoic

acid, N-acetyl cysteine and selenium, which contribute to glutathione

production. Abel notes that metabolizing and excreting acetaminophen

(Tylenol) depletes glutathione. " Tylenol is probably not the best long-term

pain reliever for anyone concerned with eye health. " He says. "

GOOGLE ON +glutathione+tylenol

http://www.gotdownsyndrome.net/glutathione & acetaminophen.html

Glutathione & The Acetaminophen (active ingredient in Tylenol) Issue:

Glutathione is commonly deficient in individuals with Down Syndrome, due to

the extra chromosome & overexpression of the SOD-1 gene. Glutathione is an

important antioxidant. It helps scavenge free radicals, deal with oxidative

stress & the pro-oxidant state of individuals with Down Syndrome.

Acetaminophen (the active ingredient in Tylenol & many other OTC drugs),

depletes Glutathione levels in the liver (where it is made & stored).

Therefore, for a person with Down Syndrome, this situation is very

important. Since Acetaminophen depletes Glutathione (which is already

deficient in DS), it is a bad situation - a key antioxidant is being even

more depleted. It can then cause more oxidative damage, free radicals &

liver damage. Tylenol is known to possibly cause liver damage & failure. It

is best if Tylenol (and drugs containing Acetaminophen) be avoided, but if

it is necessary, they can be used at times. When you have to use them, just

make sure you give more Glutathione or N-acetyl-cysteine to help out!

Below, is alot of info on Glutathione & the Acetaminophen issue (since it

is an important issue that comes up fairly often on DS lists):

The following is a list of some of the drugs that contain Acetaminophen:

Actifed Plus

Anacin (all products)

Benadryl (Plus and Plus Nighttime)

Comtrex (all products)

Dristan (all products except Room Vaporizer)

Drixoral Plus

Excedrin (all products)

Nyquil Nighttime Cold Medicine

Pamprin (all products)

Panadol, Children's and Infant's

Percogesic

Sinutab (all products)

Sominex Pain Relief Formula 1 Tablets

TheraFlu (all products)

Tylenol (all products)

Paracetomal

from:

http://www.mdanderson.org/topics/paincontrol/display.cfm?id=34E2C00E-5D6A-44

A1-8317170F0DAB8D54 & method=displayFull

This article is one of the best articles I have seen on Glutathione. It

talks about the numerous things that Glutathione is involved with. It also

talks about Acetaminophen & Glutathione. The article also does not talk

with too many " big words " & things that are really hard to understand.

http://www.thorne.com/altmedrev/fulltext/glut.html

Here are a couple quotes from the above article about Acetaminophen (with a

few notes of mine):

" Many pharmaceutical products are oxidants capable of depleting GSH [my

note: Glutathione] from the liver, kidneys, heart, and other tissues.29 The

popular over-the-counter drug acetaminophen [my note: active ingredient inÂ

Tylenol] is a potent oxidant [my note: it creates oxidation - free

radicals]. It depletes GSH from the cells of the liver [my note: which is

where GSH is made & stored], and by so doing renders the liver more

vulnerable to toxic damage. "

" The consequences of sustained GSH depletion are grim. As cellular GSH is

depleted, first individual cells die in those areas most affected [my note:

we have lots of cell death already going on in DS]. Then zones of tissue

damage begin to appear; those tissues with the highest content of

polyunsaturated lipids and/or the most meager antioxidant defenses are

generally the most vulnerable. Localized free-radical damage [my note:

which is an issue in DS, due to low antioxidant levels & high oxidative

stress] spreads across the tissue in an ever-widening, self-propagating

wave. If this spreading wave of tissue degeneration is to be halted, the

antioxidant defenses must be augmented. "

This is an interesting abstract that says that Resveratrol helps against

the toxicity done by Acetaminophen. Resveratrol is a potent antioxidant -

it is from the skin of grapes. If you have to give Tylenol, it sounds like

it'd be very beneficial to give Resveratrol also:

Protective effects of resveratrol against acetaminophen-induced toxicity in

mice.

Marmara University, School of Pharmacy, Departments of Pharmacology,

Istanbul, Turkey.

This investigation elucidates the role of free radicals in acetaminophen

(AA)-induced toxicity and the possible protection by resveratrol (RVT).

BALB-c mice were injected with a single dose of 900mg/kg AA to induce

toxicity, while RVT administred in a dose of 30mg/kg i.p. following AA.

Mice were sacrificed 4h after AA injection to determine serum ALT, AST and

tumor necrosis factor-alpha (TNF-alpha) levels in blood, and glutathione

(GSH), malondialdehyde (MDA) levels, myeloperoxidase (MPO) activity and

collagen contents in liver tissues. Formation of reactive oxygen species in

hepatic tissue samples was monitored by using chemiluminescence (CL)

technique with luminol and lucigenin probe. ALT, AST levels and TNF-alpha

were increased significantly after AA treatment, and reduced with RVT. AA

caused a significant decrease in GSH levels while MDA levels and MPO

activity were increased in liver tissues. On the other hand when RVT

administered following AA, depletion of GSH and accumulation of MDA and

neutrophil infiltration were reversed back to control. Furthermore

increased luminol and lucigenin CL levels in the AA group reduced by RVT

treatment. Our results implicate that AA causes oxidative damage in hepatic

tissues and RVT, by its potent antioxidant effects protects the liver

tissue. These data suggest that RVT may be of therapeutic use in preventing

hepatic oxidative injury due to AA toxicity.

SO STAY AWAY FROM TYLENOL... YOU ARE BETTER OFF WITH MOTRIN IF YOU MUST!!!

Love, Gabby. :0)

http://stemcellforautism.blogspot.com/

 

" I know of nobody who is purely Autistic or purely neurotypical. Even God had

some Autistic moments, which is why the planets all spin. " ~ Jerry Newport

 

 

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Do u have any info about the effects of Motrin?