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I got this article (see below) from Dr. Mercola site at:

http://articles.mercola.com/sites/articles/archive/2008/01/02/dmso-and-vitamin-b\

12.aspx

Has anybody ever tried this..... I am considering giving it a test go on myself!

DMSO and Vitamin B12

by Dr. Gregg

There have been a number of publications reporting studies showing that

breathing nitrous oxide may destroy a person's vitamin B12. This has been

reported not only in journal articles, but has finally been incorporated in the

latest books on nutritional supplements as well as books on biochemistry. What

first came to my mind was the use of this gas by dentists.

Nitrous oxide, often called " laughing gas, " is commonly used by dentists

to help mitigate pain. This could present a risk to patients, but probably more

often it presents a risk to people working in the office who would be exposed

every day. However, a far greater potential concern came to mind when I recently

read a news article that stated that the catalytic converters in automobiles are

creating enough nitrous oxide emissions to contribute significantly to the

greenhouse effect. It is also known to be a very stable molecule that has a

lifetime in the atmosphere of approximately 150 years.

With cars continuing to produce it, one would expect the concentration in

the atmosphere, world wide, to be increasing every year, and it appears to be

doing so. Is this already producing B12 deficiencies world wide, which will

increase with time? This would not be surprising because we require (and absorb)

only a few micrograms of vitamin B12 per day and our livers store only a few

micrograms in reserve. It would take only a very low concentration of nitrous

oxide in the atmosphere to destroy this if the destruction process is efficient,

and the individual's dietary absorption process is inefficient. What are the

potential health consequences and what can we as individuals do to protect

against this potential problem?

I have had some personal experience which I will discuss below that makes

me believe that I have discovered a significant fraction of the population is

B12 deficient. It is a far greater fraction that I would have expected, since it

even exists in young people who should have healthy B12 absorption systems. Is

this the effect of the atmospheric nitrous oxide emissions already showing up? I

believe it is a definite possibility which deserves some serious attention.

Health Consequences of a Vitamin B12 Deficiency

It is widely recognized that vitamin B12 in combination with folic acid is

essential for your body to synthesize hemoglobin. A deficiency can result in a

particular form of anemia called pernicious anemia. However, as we continually

expand our knowledge of biochemistry, it is being recognized that these vitamins

fill far more broad ranging requirements. It is doubtful that all their

functions been identified, but it is reasonable to conclude that a deficiency

could result in or contribute to a broad range of degenerative processes.

The absorption of vitamin B12 requires a highly specialized process which

tends to become less effective with age. For this reason it is common for

doctors to give elderly people B12 shots which result in them feeling much

better and more energetic. It is also common for the elderly to develop numerous

degenerative diseases. (They don't all get shots.)

Does a B12 (and folic acid) deficiency contribute to the development of

many degenerative diseases that we commonly associate with aging? It would not

surprise me at all if it does. It doesn't appear to be so common to give vitamin

B12 shots to young people, so we may have not discovered a deficiency that may

exist. Is there a similar deficiency in younger people resulting in a different

set of medical problems? I have reason to believe there might be, and my only

explanation for such a surprising and unnatural development is the growing

nitrous oxide concentration in the atmosphere.

The individual solutions and my evidence that the problem might be broad

ranging over all age groups. If a serious vitamin B12 deficiency is being caused

by automobile emissions, we certainly want to change that process. However, this

will require changes in cars that are beyond our individual control. So, what

can we do individually?

I am a strong believer in oral dietary supplements. It is the best start.

You can get B12 and folic acid supplements at any health food store and follow

the directions on the label. Since vitamin B12 requires a special absorption

system that may not be healthy in a particular individual, some people may not

benefit from oral supplements.

For such people, one form of B12 is available, called sublingual tablets,

which are designed to be held under the tongue while the B12 is absorbed through

the skin. Many may find this approach to be advantageous. Available by

prescription are B12 shots, which may have to be administered by a doctor. I

discovered another approach which I experimented with personally and which

eventually led me to discover what I interpreted to be a very common Vitamin B12

deficiency, independent of the age group. This surprised and puzzled me very

much.

Back in 1994 when I was focusing on learning as much as I could about

vitamin B12, an experiment came to mind which I decided to try on myself. I saw

a bottle of DMSO (dimethylsulfoxide) on the shelf of my health food store and

remembered that DMSO is not only absorbed directly through the skin, but it also

would carry with it any impurities dissolved in it. This can be a serious

problem if the impurities are toxic.

However, I also realized that if I dissolved vitamin B12 in it, it might

carry it directly to my blood stream through my skin. I tried it and the results

were dramatic for me, far greater than any impact I had ever felt from oral or

sublingual tablets. I put some of my vitamin B12 tablets obtained at a health

food store into a two liquid ounce bottle with an eyedropper and filled it with

DMSO. It took a couple of days for the tablets to fall apart. Once they did, I

put an eyedropper load on one arm and rubbed it in. In approximately one hour I

started to feel very good, which was a sense of general strength and well being.

This lasted all day.

When I tried it again the next day, I got no such feeling. I also didn't

experience any bad effects either. Since I knew that approximately one month's

requirement of B12 is stored in your liver, I reasoned that my system was simply

fully supplied with Vitamin B12 and that I wouldn't need to use it again for a

month or so. When I tried it again a month or so later, I got a significant

boost from it again. Since then I have continued to use it on a once every month

or so basis.

With time I decided to also add folic acid and a multiviamin-multimineral

tablet to give the solution a broader base of nutritional support. I use a two

ounce bottle with an eyedropper, add 10mg of vitamin B12 (ten 1000 mcg tablets),

9.6 mg of folic acid (twelve 800 mcg tablets) and a single

multivitamin-multimineral tablet and fill it with 99.9% DMSO (leaving a bubble

at the top so it can be mixed when shaken). All ingredients were obtained from

my local health food store.

The tablets are mostly binder and take a few days to fall apart. They

don't fully dissolve, but that doesn't seem to matter in terms of potency. I now

use this regularly on approximately a once every month or two basis. It serves

as a reasonable mood elevator for me, and I believe it contributes significantly

to my general health. My interpretation is I seem to become deficient in vitamin

B12 even though I take oral supplements regularly.

Over time I have told a number of other people about this and many have

chosen to try it. (I strongly recommended that they consult their physician

first.) Of those who have chosen to make up solutions and try it, approximately

50% have told me that they noticed a very significant energy boost, and this was

not limited to elderly people. It seemed to be independent of age, from age 25

and up.

Some also found a benefit if they used it as frequently as once every two

weeks and others were like me, finding the best time span between use to be in

the once-a-month or so range. If I interpret this to indicate B12 deficiencies,

the 50% number is much higher than I would have expected, and the impact on

young people was particularly unexpected. Is this an indication that there is

something happening in our environment that is causing a broad base of Vitamin

B12 deficiencies? When I read the news article about automobile exhaust and the

production of enough nitrous oxide to affect the greenhouse effect, a light

turned on. This may the cause. If so, it is a very important issue.

It is my hope that this article will stimulate a thorough investigation

into this issue to systematically evaluate if it is true, and result in an

organized effort towards a solution.

--------------------------------------------------------------------------

Dr. Mercola's Comment:

I have not used Dr. Gregg's approach, yet. It certainly seems to be a safe

alternative, though, for those who do not want to use vitamin B12 injections.

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We've never tried it, but love the shots for Tyler. I would love an

effective way to test mb12 on without shots. (He doesn't

currently see a DAN doctor.) If you try it, let me know if you see

any noticeable effects.

in NJ

> I got this article (see below) from Dr. Mercola site at:

http://articles.mercola.com/sites/articles/archive/2008/01/02/dmso-

and-vitamin-b12.aspx

>

> Has anybody ever tried this..... I am considering giving it a test

go on myself!

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