Egg Phosphatidylcholine in Health;

[Guest guest]

http://sciencelinks.jp/j-east/article/200521/000020052105A0683743.php

Hen Egg Phosphatidylcholine in Health; Hen egg phosphatidylcholine combined with

vitamin B12 improved memory dysfunction in brain

Accession number;05A0683743

Title;Hen Egg Phosphatidylcholine in Health; Hen egg phosphatidylcholine

combined with

vitamin B12 improved memory dysfunction in brain

Author;MASUDA YASUNOBU(Res. Inst. Q.P. Corp., JPN)

Journal Title;Associate Journal of Japanese Society for Medical Use of

Functional Foods

Journal Code:G0430C

ISSN:1348-2564

VOL.2;NO.6;PAGE.343-348(2005)

Figure & Table & Reference;FIG.2, TBL.2, REF.18

Pub. Country;Japan

Language;Japanese

Abstract;The lowering of Ach amount in the brain by the aging is estimated as a

cause of

learning memory lowering. Though Ach in the brain is synthesized from acetyl CoA

and

choline, choline must be depended on dietary intake. It is necessary to take in

choline as

the phospholipid for efficient intake of choline. Phosphatidylcholine (PC), a

phospholipid

as a supply source of choline, is included in the egg yolk at a high content. In

this paper,

the effect on cerebral function by combined use of egg yolk PC and vitamin B12

is

examined. It was indicated that the combined use of egg yolk PC and VB12

promotes

recovery from learning memory disorder through the brain cholinergic system,

when the

effect on brain Ach concentration and learning memory was examined in the

fore-brain

nucleus basalis damage rat. Also, in an aging-promoted mouse, hippocampus PKC

activity

and ratio of DHA in the phosphatidylethanolamine of the cerebrum increased by

the

combined use of egg yolk PC and VB12, and the possibility of useful effect on

hippocampus PKC activity lowering by the aging and fatty acid composition of the

brain

was indicated. In addition, the combined use of egg yolk PC and VB12 improved

the

cognition disorder of Alzheimer disease also in the clinic, and the usefulness

for psychic

function injury of senile dementia was indicated. From the above, it was

considered that

since the combined use of egg yolk PC and VB12 shows improving effect on

cerebral

function failure, it is a functional material suitable for the maintenance of

the health of

the brain.

BACK