Re: Update on Tanner on Nutriiveda/interesting new study

[Guest guest]

Hi Lis,

Happy New Year - May 2010 be filled with WONDERFUL things for you and your

family!

I'm trying to register on the big tent website and this is the 2nd time, i'm not

able to...?!

Any ideas on how to make it work?? Also, can you send me the updated photos/link

to

see Tanner!!! !NO WAY he is 5/8 " .....almost as tall as ME!?!?!?!!!

ALSO - I'm dying to hear / see the new news on ...How is she, Robin,

their family?!

I tried calling their old # the other day, around xmas time -- but think it's

not the correct #...

She's doing well? Can you update me?? I'm thrilled if she is doing great?!

Well, must go - thinking of you & sending love & best wishes,

laur

[ ] Update on Tanner on Nutriiveda/interesting new

study

Hi all!

Well I have been posting to our new BigTent group and am loving it there -but

wanted to share here as well for those of you who have not moved over yet. First

of all for those that don't know - our BigTent group which is free and private

and has way more in the arena of options to make sharing with each other better

is at https://www.bigtent.com/groups/cherab

Tanner has been on the nutriiveda since September but because it was on

backorder until mid October he really has only been on it since mid October. As

I let everyone know it wasn't only us that noticed improvements in Tanner's

speech as we got a call from his head of school who reported not only vast

improvements in speech but in focus, academics -specifically reading as he all

of a sudden was walking around reading books, alert, and not only talking better

-but much more alert and talkative throughout the day -specifically after lunch

when reportedly prior to nutriiveda after lunch he used to be " wiped out " . As

far as weight I know many of the little ones do not need to lose weight, and

this product is fine for them too, but as Tanner got older he appeared to be

putting weight on in his stomach and neck- as Dr. Agin said it looked like

something metabolic was going on (this was in spite of the fact Tanner was

tested for everything under the sun and tested negati ve) Tanner has always

eaten very healthy too. I just uploaded photos of Tanner to the photo section

here and of course they are on our BigTent group as well. Tanner is now at a

perfect weight for his height -we are thrilled with that but of course even more

with how well he is doing on this product. He lost 12 pounds and grew over an

inch since starting. He is now 5 foot 8 1/2 inches and 150 pounds (13 years old)

Since Mel is not on any fish oils at all and doing so amazing I found that to be

most interesting. Tanner when I started the nutriiveda was still on his regular

4 ProEFA and 2 ProEPA and in the past if I lowered that in any way he would

regress. Sometime after Thanksgiving I lowered Tanner cold turkey to a 1/2

dosage 2 ProEFA 1 ProEPA just to see if I noticed any regression -I didn't. I

don't want to stop the fish oils as we have heart disease in our family and know

that will help my boys no matter what but do find it interesting that Tanner did

not regress from his dosage being cut in half. I strongly feel this product is

supporting his metabolic system in some way.

For those of you who are friends of mine on fb you will know that in general

Tanner's facial expressions in photo for random photos (not the ones I hand pick

out) he doesn't always have much in the way of facial expressions. What you'll

notice when you look at the photos of Tanner in the uploads is that in every

photo he now has facial expressions. Some of you may not recall but a few years

ago Dr. Jonas and I even tried attaching electrodes to his face to try to

stimulate the nerve endings in his face to try to get his to move his facial

muscles more as his oral apraxia gave him such a blank look too much of the

time. No longer -and how easy was it.

I've been getting such great feedback from parents of children with ADHD too

(mainly teens that are on meds) that we started my son Dakota on it too. If

anyone has interest in this area let me know and I can get you the phone number

of some of the other parents. I currently have an early childhood professional

that is interested in interviewing each of the families to see what she can

learn as to why this appears to be working. She is interested in starting a blog

as well; so look for it at http://www.pursuitofreserach.org under " blogs "

So why? Is it the synergistic blend of ayurveda, protein, amino acids? I don't

know if any of us will know for sure anytime soon but do know that I don't yet

know of one doctor who has not approved this for the kids. Like the fish oils

most say they don't know if it will help in any way -but " can't hurt " So why

perhaps is it working? Well I posted the other day about the amino acid/neuro

improvement link in mice. Today I want to leave everyone with this interesting

study that to me perhaps explains possible links to metabolic/diet and neuro

conditions:

Loss of epigenetic regulators causes mental retardation

Developing neurons don't just need the right genes to guide them as they grow,

they need access to the right genes at the right times. The improper functioning

of one specific protein complex that normally suppresses gene activation is

responsible for a mental retardation-like syndrome in mice, reports a team of

scientists at The Rockefeller University. New findings, published in recent

issues of Neuron and Science, indicate that malfunction of this protein complex

causes mental retardation in mice and humans and may even play a role in

promoting susceptibility to drug addiction. The research also establishes the

complex as a key regulator of neuronal transcriptional identity.

" This research is the result of a close collaboration between our group and that

of Tarakhovsky, which is focused on understanding the role of

epigenetic mechanisms in brain function, such as learning and memory, " says

senior coauthor Greengard, Astor Professor and head of the

Laboratory of Molecular and Cellular Neuroscience. Greengard won the 2000 Nobel

Prize in Physiology or Medicine for research into how neurons communicate.

" Our findings may facilitate the identification of mechanisms responsible for

long-term storage of environmental information in neurons as well as other cell

types, " says senior coauthor Tarakhovsky, professor and

head of the Laboratory of Lymphocyte Signaling. " We now have an animal system

that not only reproduces the human disease but may also enable us to understand

the underlying mechanisms. "

Although genes provide the fixed template that instructs our cells how to grow,

increasing evidence suggests that gene activity is governed by a group of

proteins known as histones. Histones are subjected to chemical modifications

that can permit or prevent genes from becoming active. These modifications are

established by specific enzymes that add well-defined chemical residues to the

amino acids localized within the tails of the histone proteins. Histone

modifications were first identified in the early 1960s by Rockefeller scientist

Allfrey and his colleagues. During the past two decades, research by

Rockefeller University's C. Allis suggested that histone modification

could generate a unique epigenetic " code " that regulates the specific

recruitment of gene expression activators and repressors to individual genes.

The research program of the Greengard and Tarakhovsky labs focuses on GLP/G9a,

an enzyme pair responsible for inducing an epigenetic mark widely known to

silence gene expression in mammals, including humans. By attaching two methyl

chemical groups to a specific amino acid on a specific histone, GLP/G9a

suppresses gene activity. Tarakhovsky and his colleagues, who study GLP/G9a and

its role in epigenetic regulation of inflammatory responses, created a strain of

mice that enables conditional removal of this complex in various cell types,

including neurons in the adult brain.

First author Anne Schaefer, a senior research associate in Greengard's lab,

subjected these mice to a battery of behavioral tests and determined that they

behave much like humans with a mental retardation syndrome called the 9q34

deletion syndrome, in which the region of chromosome 9 that codes for the GLP

genes is missing. The mice lacking GLP/G9a, unlike their normal counterparts,

were not afraid of open space, were lethargic (and as a result, obese) and had

problems learning to adapt to their environment.

The researchers compared the brains of normal mice and the conditional knockouts

and found that there were no structural differences between them. In other

words, the behavioral and learning problems associated with the conditional

knockouts were not due to any kind of damage to the brain's structure or to the

individual neurons.

" This suppressive epigenetic mark completely disappears in these mice, but the

neurons themselves do not die and appear normal, " says Schaefer. " The mice

maintain many of their basal behavioral functions, such as eating and breeding,

but they display abnormal behavior in response to various environmental

signals. "

Schaefer and her colleagues also found that loss of GLP/G9a resulted in

increased expression of genes usually found in muscles and the heart. In

addition to their analysis of genes that change in the different brain regions,

they used a cellular analysis technique developed in labs headed by Rockefeller

scientist iel Heintz and Greengard, called TRAP, which reveals

transcriptional profiles by isolating the RNA messages from structurally and

functionally defined individual cell populations.

" We found that several nonneuronal genes, normally suppressed by the epigenetic

mark, became upregulated in the GLP/G9a conditional knockouts, " says Schaefer.

According to Schaefer and her colleagues, it's also possible that genetically

predetermined or environmentally induced changes of the epigenetic regulators

controlling the methylation mark on histone H3 may be responsible for individual

differences in learning and social adaptation.

The Greengard and Tarakhovsky labs have taken these findings a step further in

collaboration with Nestler's lab at the Mount Sinai School of Medicine. In

research reported in the the January 8 issue of the journal Science, they found

that repeated cocaine administration promotes cocaine preference in mice,

revealing a key role for G9a in drug addiction.

Epigenetic regulators are considered the " last frontier " by pharmaceutical

companies, Tarakhovsky says, because of their position in the chain of events in

cell signaling. " The major excitement of these findings is that there are very

few proteins known to have such key regulatory functions and are structurally

well defined. That means it should be possible to design drugs that specifically

interfere with their activity. "

http://newswire.rockefeller.edu/?page=engine & id=1021

=====

[Guest guest]

Thanks for sending the update on Tanner .My son (16 yr.) has also started to

regress over the last year.  I attributed it to graduating from 8th grade and

stress of starting high school. He has been on 4 complete 369 and 2 EPA Nordic

naturals.  He is also on Vit E d-Alpha800 IU and High Gamma Vit E 400IU.  He

takes all his supplements in the AM with his breakfast.  Do you still have

Tanner on Vit E? Did you transition off slowly? Where can I get the Nutriveda

and how much of a dose should I give? Nick weighs 170 and is 5'9 " .  Thanks so

much for all you do. I know that my son is much better off from using what I

have learned on this site. Hope to hear from you soon....Carol

From: kiddietalk <kiddietalk@...>

Subject: [ ] Update on Tanner on Nutriiveda/interesting new

study

Date: Saturday, January 9, 2010, 9:19 PM

 

Hi all!

Well I have been posting to our new BigTent group and am loving it there -but

wanted to share here as well for those of you who have not moved over yet.

First of all for those that don't know - our BigTent group which is free and

private and has way more in the arena of options to make sharing with each other

better is at https://www. bigtent.com/ groups/cherab

Tanner has been on the nutriiveda since September but because it was on

backorder until mid October he really has only been on it since mid October. As

I let everyone know it wasn't only us that noticed improvements in Tanner's

speech as we got a call from his head of school who reported not only vast

improvements in speech but in focus, academics -specifically reading as he all

of a sudden was walking around reading books, alert, and not only talking better

-but much more alert and talkative throughout the day -specifically after lunch

when reportedly prior to nutriiveda after lunch he used to be " wiped out " . As

far as weight I know many of the little ones do not need to lose weight, and

this product is fine for them too, but as Tanner got older he appeared to be

putting weight on in his stomach and neck- as Dr. Agin said it looked like

something metabolic was going on (this was in spite of the fact Tanner was

tested for everything under the sun and

tested negative) Tanner has always eaten very healthy too. I just uploaded

photos of Tanner to the photo section here and of course they are on our BigTent

group as well. Tanner is now at a perfect weight for his height -we are

thrilled with that but of course even more with how well he is doing on this

product. He lost 12 pounds and grew over an inch since starting. He is now 5

foot 8 1/2 inches and 150 pounds (13 years old)

Since Mel is not on any fish oils at all and doing so amazing I found that to be

most interesting. Tanner when I started the nutriiveda was still on his regular

4 ProEFA and 2 ProEPA and in the past if I lowered that in any way he would

regress. Sometime after Thanksgiving I lowered Tanner cold turkey to a 1/2

dosage 2 ProEFA 1 ProEPA just to see if I noticed any regression -I didn't. I

don't want to stop the fish oils as we have heart disease in our family and know

that will help my boys no matter what but do find it interesting that Tanner did

not regress from his dosage being cut in half. I strongly feel this product is

supporting his metabolic system in some way.

For those of you who are friends of mine on fb you will know that in general

Tanner's facial expressions in photo for random photos (not the ones I hand pick

out) he doesn't always have much in the way of facial expressions. What you'll

notice when you look at the photos of Tanner in the uploads is that in every

photo he now has facial expressions. Some of you may not recall but a few years

ago Dr. Jonas and I even tried attaching electrodes to his face to try to

stimulate the nerve endings in his face to try to get his to move his facial

muscles more as his oral apraxia gave him such a blank look too much of the

time. No longer -and how easy was it.

I've been getting such great feedback from parents of children with ADHD too

(mainly teens that are on meds) that we started my son Dakota on it too. If

anyone has interest in this area let me know and I can get you the phone number

of some of the other parents. I currently have an early childhood professional

that is interested in interviewing each of the families to see what she can

learn as to why this appears to be working. She is interested in starting a

blog as well; so look for it at http://www.pursuito freserach. org under " blogs "

So why? Is it the synergistic blend of ayurveda, protein, amino acids? I don't

know if any of us will know for sure anytime soon but do know that I don't yet

know of one doctor who has not approved this for the kids. Like the fish oils

most say they don't know if it will help in any way -but " can't hurt " So why

perhaps is it working? Well I posted the other day about the amino acid/neuro

improvement link in mice. Today I want to leave everyone with this interesting

study that to me perhaps explains possible links to metabolic/diet and neuro

conditions:

Loss of epigenetic regulators causes mental retardation

Developing neurons don't just need the right genes to guide them as they grow,

they need access to the right genes at the right times. The improper functioning

of one specific protein complex that normally suppresses gene activation is

responsible for a mental retardation- like syndrome in mice, reports a team of

scientists at The Rockefeller University. New findings, published in recent

issues of Neuron and Science, indicate that malfunction of this protein complex

causes mental retardation in mice and humans and may even play a role in

promoting susceptibility to drug addiction. The research also establishes the

complex as a key regulator of neuronal transcriptional identity.

" This research is the result of a close collaboration between our group and that

of Tarakhovsky, which is focused on understanding the role of

epigenetic mechanisms in brain function, such as learning and memory, " says

senior coauthor Greengard, Astor Professor and head of the

Laboratory of Molecular and Cellular Neuroscience. Greengard won the 2000 Nobel

Prize in Physiology or Medicine for research into how neurons communicate.

" Our findings may facilitate the identification of mechanisms responsible for

long-term storage of environmental information in neurons as well as other cell

types, " says senior coauthor Tarakhovsky, professor and

head of the Laboratory of Lymphocyte Signaling. " We now have an animal system

that not only reproduces the human disease but may also enable us to understand

the underlying mechanisms. "

Although genes provide the fixed template that instructs our cells how to grow,

increasing evidence suggests that gene activity is governed by a group of

proteins known as histones. Histones are subjected to chemical modifications

that can permit or prevent genes from becoming active. These modifications are

established by specific enzymes that add well-defined chemical residues to the

amino acids localized within the tails of the histone proteins. Histone

modifications were first identified in the early 1960s by Rockefeller scientist

Allfrey and his colleagues. During the past two decades, research by

Rockefeller University's C. Allis suggested that histone modification

could generate a unique epigenetic " code " that regulates the specific

recruitment of gene expression activators and repressors to individual genes.

The research program of the Greengard and Tarakhovsky labs focuses on GLP/G9a,

an enzyme pair responsible for inducing an epigenetic mark widely known to

silence gene expression in mammals, including humans. By attaching two methyl

chemical groups to a specific amino acid on a specific histone, GLP/G9a

suppresses gene activity. Tarakhovsky and his colleagues, who study GLP/G9a and

its role in epigenetic regulation of inflammatory responses, created a strain of

mice that enables conditional removal of this complex in various cell types,

including neurons in the adult brain.

First author Anne Schaefer, a senior research associate in Greengard's lab,

subjected these mice to a battery of behavioral tests and determined that they

behave much like humans with a mental retardation syndrome called the 9q34

deletion syndrome, in which the region of chromosome 9 that codes for the GLP

genes is missing. The mice lacking GLP/G9a, unlike their normal counterparts,

were not afraid of open space, were lethargic (and as a result, obese) and had

problems learning to adapt to their environment.

The researchers compared the brains of normal mice and the conditional knockouts

and found that there were no structural differences between them. In other

words, the behavioral and learning problems associated with the conditional

knockouts were not due to any kind of damage to the brain's structure or to the

individual neurons.

" This suppressive epigenetic mark completely disappears in these mice, but the

neurons themselves do not die and appear normal, " says Schaefer. " The mice

maintain many of their basal behavioral functions, such as eating and breeding,

but they display abnormal behavior in response to various environmental

signals. "

Schaefer and her colleagues also found that loss of GLP/G9a resulted in

increased expression of genes usually found in muscles and the heart. In

addition to their analysis of genes that change in the different brain regions,

they used a cellular analysis technique developed in labs headed by Rockefeller

scientist iel Heintz and Greengard, called TRAP, which reveals

transcriptional profiles by isolating the RNA messages from structurally and

functionally defined individual cell populations.

" We found that several nonneuronal genes, normally suppressed by the epigenetic

mark, became upregulated in the GLP/G9a conditional knockouts, " says Schaefer.

According to Schaefer and her colleagues, it's also possible that genetically

predetermined or environmentally induced changes of the epigenetic regulators

controlling the methylation mark on histone H3 may be responsible for individual

differences in learning and social adaptation.

The Greengard and Tarakhovsky labs have taken these findings a step further in

collaboration with Nestler's lab at the Mount Sinai School of Medicine. In

research reported in the the January 8 issue of the journal Science, they found

that repeated cocaine administration promotes cocaine preference in mice,

revealing a key role for G9a in drug addiction.

Epigenetic regulators are considered the " last frontier " by pharmaceutical

companies, Tarakhovsky says, because of their position in the chain of events in

cell signaling. " The major excitement of these findings is that there are very

few proteins known to have such key regulatory functions and are structurally

well defined. That means it should be possible to design drugs that specifically

interfere with their activity. "

http://newswire. rockefeller. edu/?page= engine & id= 1021

=====

[Guest guest]

Hi Carol!

While Tanner had done well on the low dosage of vitamin e for about 2 years

-Tanner's had to be off all vitamin e since his massive regression on the

product called Speak which has mega dosages of vitamin E and K (may want to read

this to learn more why

http://www.facebook.com/topic.php?uid=115029735601 & topic=10637 )

For Tanner he no longer is on any supplements at all except 2 ProEFA and 1

ProEPA once a day and nutriiveda. I didn't think anything of Tanner being on

the 4 ProEFA and 2 ProEPA he was on for years...but once on the Nutriiveda his

speech SURGED- and not just speech but amount of speech, clarity, complexity

-and his surge was in academics and facial expressions. His grades have gone up

and he's not the only one. I have been posting quite a few recent studies on

Facebook and to our BigTent group about the new research coming out showing the

possible links between nutrition/amino acids and protein to neurological

function and repair.

Since your son is closer to Tanner's age and on/has been on the same supplements

-please check the nutriiveda out with his doctor and any friends you have that

are nutritionists etc. Everyone I have shown it to have been very impressed

with it and I was told if nothing else it's good nutrition loaded with easily

digestible protein and all the essential amino acids etc.. The synergistic

blend of ayurveda is something we are all learning in this group but Sowmya

from our group is from India and she says while they may be new things to most

of us -to her they are every day items used in the diet. There are no known

side effects, drug interactions, or overdosage warnings on the product. In this

group I do tell parents about the vitamin a but from what I can gather the

turmeric is very high in beta carotene. Please call me with any questions 773

335 5135. It will be SO cool to hear that like my son Tanner who's one of our

older 'children' (and of course Mel) that you see a surge that brings your son

up on all aspects. I mean I an honestly say that Tanner is as close to " normal "

now as whatever normal is. I don't discredit the years of therapy and fish oils

etc....but since the surges were so rapid on the nutriiveda I do believe this

metabolic product somehow was so needed by him. He seems to be aware of it as

well and asks for it. I have my ADHD son Dakota on it for lunch every day now

(he never wants to eat lunch -and he's a horrible eater unlike Tanner) That was

due to the 4 friend's kids - all teens -who went on the nutriiveda to lose a few

pounds and the side benefit is that all went to straight A students from B and C

students...well Josh had even more issues and jumped around a few schools and is

now " excelling " and straight As since on this. I find that too strange to make

it coincidence. The fish oils always sounded too good to be true too -I'm sure

like the fish oils there is a logical scientific explanation as to what's going

on. Somehow I suspect if we start exploring some of the recent studies we'll

unlock more answers.

=====

[Guest guest]

-

I started my 4 year old on Nutriiveda on Friday... Have finally figured

out how to give it to her easily (just blend it up in a blender and give to her

in sippy and she sucks it dry!)  I give her 2 scoops in the morning.  I have

not personally seen any changes in her - but she is in school today and therapy

tomorrow so maybe they will see some changes as they work with her.  I am not

giving up hope and if nothing else, it's good for her to get the additional

protiens, etc.  Her pediatrician, and my father (MD) both saw nothing wrong

with giving it to her as you say below no dr.'s have said anything other than

" it can't hurt " ...  One thing I have noticed and I'm not sure if it's just her

but she won't eat bkfst - like she is full - after drinking it... But she was

never a huge bkfst person anyway so I'm not terribly worried... I was tryig to

give it to her in yogurt but that only frustrated me and she didn't eat it all

b/c there was so

much of it and I could only do 1 scoop at a time... So now she sucks it down in

a drink...

Any thoughts on if I should do anything different?  And she does just get the

2 scoops right?

I will keep you updated on her progress, but so far as everything else we have

done for her - no changes...

  Cristal

gtzellner@...

________________________________

From: kiddietalk <kiddietalk@...>

Sent: Sun, January 10, 2010 12:19:51 AM

Subject: [ ] Update on Tanner on Nutriiveda/interesting new

study

 

Hi all!

Well I have been posting to our new BigTent group and am loving it there -but

wanted to share here as well for those of you who have not moved over yet. First

of all for those that don't know - our BigTent group which is free and private

and has way more in the arena of options to make sharing with each other better

is at https://www. bigtent.com/ groups/cherab

Tanner has been on the nutriiveda since September but because it was on

backorder until mid October he really has only been on it since mid October. As

I let everyone know it wasn't only us that noticed improvements in Tanner's

speech as we got a call from his head of school who reported not only vast

improvements in speech but in focus, academics -specifically reading as he all

of a sudden was walking around reading books, alert, and not only talking better

-but much more alert and talkative throughout the day -specifically after lunch

when reportedly prior to nutriiveda after lunch he used to be " wiped out " . As

far as weight I know many of the little ones do not need to lose weight, and

this product is fine for them too, but as Tanner got older he appeared to be

putting weight on in his stomach and neck- as Dr. Agin said it looked like

something metabolic was going on (this was in spite of the fact Tanner was

tested for everything under the sun and

tested negative) Tanner has always eaten very healthy too. I just uploaded

photos of Tanner to the photo section here and of course they are on our BigTent

group as well. Tanner is now at a perfect weight for his height -we are thrilled

with that but of course even more with how well he is doing on this product. He

lost 12 pounds and grew over an inch since starting. He is now 5 foot 8 1/2

inches and 150 pounds (13 years old)

Since Mel is not on any fish oils at all and doing so amazing I found that to be

most interesting. Tanner when I started the nutriiveda was still on his regular

4 ProEFA and 2 ProEPA and in the past if I lowered that in any way he would

regress. Sometime after Thanksgiving I lowered Tanner cold turkey to a 1/2

dosage 2 ProEFA 1 ProEPA just to see if I noticed any regression -I didn't. I

don't want to stop the fish oils as we have heart disease in our family and know

that will help my boys no matter what but do find it interesting that Tanner did

not regress from his dosage being cut in half. I strongly feel this product is

supporting his metabolic system in some way.

For those of you who are friends of mine on fb you will know that in general

Tanner's facial expressions in photo for random photos (not the ones I hand pick

out) he doesn't always have much in the way of facial expressions. What you'll

notice when you look at the photos of Tanner in the uploads is that in every

photo he now has facial expressions. Some of you may not recall but a few years

ago Dr. Jonas and I even tried attaching electrodes to his face to try to

stimulate the nerve endings in his face to try to get his to move his facial

muscles more as his oral apraxia gave him such a blank look too much of the

time. No longer -and how easy was it.

I've been getting such great feedback from parents of children with ADHD too

(mainly teens that are on meds) that we started my son Dakota on it too. If

anyone has interest in this area let me know and I can get you the phone number

of some of the other parents. I currently have an early childhood professional

that is interested in interviewing each of the families to see what she can

learn as to why this appears to be working. She is interested in starting a blog

as well; so look for it at http://www.pursuito freserach. org under " blogs "

So why? Is it the synergistic blend of ayurveda, protein, amino acids? I don't

know if any of us will know for sure anytime soon but do know that I don't yet

know of one doctor who has not approved this for the kids. Like the fish oils

most say they don't know if it will help in any way -but " can't hurt " So why

perhaps is it working? Well I posted the other day about the amino acid/neuro

improvement link in mice. Today I want to leave everyone with this interesting

study that to me perhaps explains possible links to metabolic/diet and neuro

conditions:

Loss of epigenetic regulators causes mental retardation

Developing neurons don't just need the right genes to guide them as they grow,

they need access to the right genes at the right times. The improper functioning

of one specific protein complex that normally suppresses gene activation is

responsible for a mental retardation- like syndrome in mice, reports a team of

scientists at The Rockefeller University. New findings, published in recent

issues of Neuron and Science, indicate that malfunction of this protein complex

causes mental retardation in mice and humans and may even play a role in

promoting susceptibility to drug addiction. The research also establishes the

complex as a key regulator of neuronal transcriptional identity.

" This research is the result of a close collaboration between our group and that

of Tarakhovsky, which is focused on understanding the role of

epigenetic mechanisms in brain function, such as learning and memory, " says

senior coauthor Greengard, Astor Professor and head of the

Laboratory of Molecular and Cellular Neuroscience. Greengard won the 2000 Nobel

Prize in Physiology or Medicine for research into how neurons communicate.

" Our findings may facilitate the identification of mechanisms responsible for

long-term storage of environmental information in neurons as well as other cell

types, " says senior coauthor Tarakhovsky, professor and

head of the Laboratory of Lymphocyte Signaling. " We now have an animal system

that not only reproduces the human disease but may also enable us to understand

the underlying mechanisms. "

Although genes provide the fixed template that instructs our cells how to grow,

increasing evidence suggests that gene activity is governed by a group of

proteins known as histones. Histones are subjected to chemical modifications

that can permit or prevent genes from becoming active. These modifications are

established by specific enzymes that add well-defined chemical residues to the

amino acids localized within the tails of the histone proteins. Histone

modifications were first identified in the early 1960s by Rockefeller scientist

Allfrey and his colleagues. During the past two decades, research by

Rockefeller University's C. Allis suggested that histone modification

could generate a unique epigenetic " code " that regulates the specific

recruitment of gene expression activators and repressors to individual genes.

The research program of the Greengard and Tarakhovsky labs focuses on GLP/G9a,

an enzyme pair responsible for inducing an epigenetic mark widely known to

silence gene expression in mammals, including humans. By attaching two methyl

chemical groups to a specific amino acid on a specific histone, GLP/G9a

suppresses gene activity. Tarakhovsky and his colleagues, who study GLP/G9a and

its role in epigenetic regulation of inflammatory responses, created a strain of

mice that enables conditional removal of this complex in various cell types,

including neurons in the adult brain.

First author Anne Schaefer, a senior research associate in Greengard's lab,

subjected these mice to a battery of behavioral tests and determined that they

behave much like humans with a mental retardation syndrome called the 9q34

deletion syndrome, in which the region of chromosome 9 that codes for the GLP

genes is missing. The mice lacking GLP/G9a, unlike their normal counterparts,

were not afraid of open space, were lethargic (and as a result, obese) and had

problems learning to adapt to their environment.

The researchers compared the brains of normal mice and the conditional knockouts

and found that there were no structural differences between them. In other

words, the behavioral and learning problems associated with the conditional

knockouts were not due to any kind of damage to the brain's structure or to the

individual neurons.

" This suppressive epigenetic mark completely disappears in these mice, but the

neurons themselves do not die and appear normal, " says Schaefer. " The mice

maintain many of their basal behavioral functions, such as eating and breeding,

but they display abnormal behavior in response to various environmental

signals. "

Schaefer and her colleagues also found that loss of GLP/G9a resulted in

increased expression of genes usually found in muscles and the heart. In

addition to their analysis of genes that change in the different brain regions,

they used a cellular analysis technique developed in labs headed by Rockefeller

scientist iel Heintz and Greengard, called TRAP, which reveals

transcriptional profiles by isolating the RNA messages from structurally and

functionally defined individual cell populations.

" We found that several nonneuronal genes, normally suppressed by the epigenetic

mark, became upregulated in the GLP/G9a conditional knockouts, " says Schaefer.

According to Schaefer and her colleagues, it's also possible that genetically

predetermined or environmentally induced changes of the epigenetic regulators

controlling the methylation mark on histone H3 may be responsible for individual

differences in learning and social adaptation.

The Greengard and Tarakhovsky labs have taken these findings a step further in

collaboration with Nestler's lab at the Mount Sinai School of Medicine. In

research reported in the the January 8 issue of the journal Science, they found

that repeated cocaine administration promotes cocaine preference in mice,

revealing a key role for G9a in drug addiction.

Epigenetic regulators are considered the " last frontier " by pharmaceutical

companies, Tarakhovsky says, because of their position in the chain of events in

cell signaling. " The major excitement of these findings is that there are very

few proteins known to have such key regulatory functions and are structurally

well defined. That means it should be possible to design drugs that specifically

interfere with their activity. "

http://newswire. rockefeller. edu/?page= engine & id= 1021

=====

[Guest guest]

The nutriiveda can be used as meal replacement and it does fill you up. In

other words even without other foods it's supposed to supply us with all the

essential nutrients we need for that one meal. My son Dakota who is now 15 is

like your daughter in that he would skip right by lunch and never eat it -even

with food put in front of him. He's thin and a very picky eater and I've always

been concerned he doesn't eat enough. We now give him a shake for lunch (we mix

it up in a water bottle) and it's worked out great as I know he'll eat breakfast

and dinner. I know for most of the kids we don't want that -so what I would do

is split the dosage of 2 scoops in half so that she won't feel so full. My

friend in a doctor in internal medicine and she feels that for the

little ones that may be better anyway so they are getting the nutrients

throughout the day. Ask her pediatrician and your dad what they think of that.

Thanks so much for sharing!!

=====

[Guest guest]

Hi, how much is the nutriiveda?

>

> Hi all!

>

> Well I have been posting to our new BigTent group and am loving it there -but

wanted to share here as well for those of you who have not moved over yet.

First of all for those that don't know - our BigTent group which is free and

private and has way more in the arena of options to make sharing with each other

better is at https://www.bigtent.com/groups/cherab

>

>

[Guest guest]

Hi , I am a mom of a 3.5yr old apricot son and I have him on the oils. He is

speaking now for 6 months but still has a long way to go. My question is about

the nutriiveda...it is advertised as a weight loss product so it is still safe

for a 3 year old who can't afford to loose any weight? It sounds like I would

give it a shot but I'm concerned about him loosing weight. Also it says it

increases energy do u think it will hype up a small child? Finally how long

did it take for u to see results? Thank you for any info u can provide.

AnnMarie

Sent from my Verizon Wireless BlackBerry

[ ] Re: Update on Tanner on Nutriiveda/interesting

new study

Hi Carol!

While Tanner had done well on the low dosage of vitamin e for about 2 years

-Tanner's had to be off all vitamin e since his massive regression on the

product called Speak which has mega dosages of vitamin E and K (may want to read

this to learn more why

http://www.facebook.com/topic.php?uid=115029735601 & topic=10637 )

For Tanner he no longer is on any supplements at all except 2 ProEFA and 1

ProEPA once a day and nutriiveda. I didn't think anything of Tanner being on

the 4 ProEFA and 2 ProEPA he was on for years...but once on the Nutriiveda his

speech SURGED- and not just speech but amount of speech, clarity, complexity

-and his surge was in academics and facial expressions. His grades have gone up

and he's not the only one. I have been posting quite a few recent studies on

Facebook and to our BigTent group about the new research coming out showing the

possible links between nutrition/amino acids and protein to neurological

function and repair.

Since your son is closer to Tanner's age and on/has been on the same supplements

-please check the nutriiveda out with his doctor and any friends you have that

are nutritionists etc. Everyone I have shown it to have been very impressed

with it and I was told if nothing else it's good nutrition loaded with easily

digestible protein and all the essential amino acids etc.. The synergistic

blend of ayurveda is something we are all learning in this group but Sowmya

from our group is from India and she says while they may be new things to most

of us -to her they are every day items used in the diet. There are no known

side effects, drug interactions, or overdosage warnings on the product. In this

group I do tell parents about the vitamin a but from what I can gather the

turmeric is very high in beta carotene. Please call me with any questions 773

335 5135. It will be SO cool to hear that like my son Tanner who's one of our

older 'children' (and of course Mel) that you see a

surge that brings your son up on all aspects. I mean I an honestly say that

Tanner is as close to " normal " now as whatever normal is. I don't discredit the

years of therapy and fish oils etc....but since the surges were so rapid on the

nutriiveda I do believe this metabolic product somehow was so needed by him. He

seems to be aware of it as well and asks for it. I have my ADHD son Dakota on

it for lunch every day now (he never wants to eat lunch -and he's a horrible

eater unlike Tanner) That was due to the 4 friend's kids - all teens -who went

on the nutriiveda to lose a few pounds and the side benefit is that all went to

straight A students from B and C students...well Josh had even more issues and

jumped around a few schools and is now " excelling " and straight As since on

this. I find that too strange to make it coincidence. The fish oils always

sounded too good to be true too -I'm sure like the fish oils there is a logical

scientific explanation as to what's going

on. Somehow I suspect if we start exploring some of the recent studies we'll

unlock more answers.

=====

[Guest guest]

AnnMarie,

Yes, it is safe for a 3.5yr old. Since NV was designed as a weight

management tool, it has not caused any of the kids to lose weight. All the

MDs who have reviewed it have said that is safe as well.

Here is the dosage by age: <4yrs= 1 scoop/day; 4-8yrs= 2 scoops/day; 9+yrs=

4 scoops/day

It is recommended to start with half the dose and then increase the next

week. Also it is recommended to split the full dose in half and give it

2x/day. So for 1 scoop, give 1/2 scoop in am and 1/2 scoop in afternoon or

pm.

As far as the energy, one of my clients' developmental pediatricians

recommends to start with 1/2 dose to make sure it doesn't affect your child

in that way. I haven't heard reports of 'too' much energy. I drink it and

notice that I have sufficient energy to get through the day w/o caffeine.

will have to report on how long it took until she saw changes in

Tanner. As I remember, only a week or 2.

Let me know what other questions you may have.

Warmest wishes,

Barbara

Barbara A. , M.S., CCC-SLP

Executive Director/ Help Me Speak, LLC

http://www.helpmespeak.com

(o) 410-442-9791 (f) 410-442-9783

2500 Wallington Way; Suite 103

Marriottsville, MD 21104

follow us on FaceBook:

http://www.facebook.com/pages/Marriottsville-MD/Help-Me-Speak-LLC/1046288520

32

Efusjon Energy Club http://www.myefusjon.com/barbarataylor

call me before you join!

Lose weight w/ NutriVeda! http://www.barbarataylor.myzrii.com

[ ] Re: Update on Tanner on

Nutriiveda/interesting new study

Hi Carol!

While Tanner had done well on the low dosage of vitamin e for about 2 years

-Tanner's had to be off all vitamin e since his massive regression on the

product called Speak which has mega dosages of vitamin E and K (may want to

read this to learn more why

http://www.facebook.com/topic.php?uid=115029735601 & topic=10637 )

For Tanner he no longer is on any supplements at all except 2 ProEFA and 1

ProEPA once a day and nutriiveda. I didn't think anything of Tanner being

on the 4 ProEFA and 2 ProEPA he was on for years...but once on the

Nutriiveda his speech SURGED- and not just speech but amount of speech,

clarity, complexity -and his surge was in academics and facial expressions.

His grades have gone up and he's not the only one. I have been posting

quite a few recent studies on Facebook and to our BigTent group about the

new research coming out showing the possible links between nutrition/amino

acids and protein to neurological function and repair.

Since your son is closer to Tanner's age and on/has been on the same

supplements -please check the nutriiveda out with his doctor and any friends

you have that are nutritionists etc. Everyone I have shown it to have been

very impressed with it and I was told if nothing else it's good nutrition

loaded with easily digestible protein and all the essential amino acids

etc.. The synergistic blend of ayurveda is something we are all learning

in this group but Sowmya from our group is from India and she says while

they may be new things to most of us -to her they are every day items used

in the diet. There are no known side effects, drug interactions, or

overdosage warnings on the product. In this group I do tell parents about

the vitamin a but from what I can gather the turmeric is very high in beta

carotene. Please call me with any questions 773 335 5135. It will be SO

cool to hear that like my son Tanner who's one of our older 'children' (and

of course Mel) that you see a

surge that brings your son up on all aspects. I mean I an honestly say

that Tanner is as close to " normal " now as whatever normal is. I don't

discredit the years of therapy and fish oils etc....but since the surges

were so rapid on the nutriiveda I do believe this metabolic product somehow

was so needed by him. He seems to be aware of it as well and asks for it.

I have my ADHD son Dakota on it for lunch every day now (he never wants to

eat lunch -and he's a horrible eater unlike Tanner) That was due to the 4

friend's kids - all teens -who went on the nutriiveda to lose a few pounds

and the side benefit is that all went to straight A students from B and C

students...well Josh had even more issues and jumped around a few schools

and is now " excelling " and straight As since on this. I find that too

strange to make it coincidence. The fish oils always sounded too good to be

true too -I'm sure like the fish oils there is a logical scientific

explanation as to what's going

on. Somehow I suspect if we start exploring some of the recent studies

we'll unlock more answers.

=====

[Guest guest]

Correction---it has not caused any kids who didn’t NEED to lose wt to lose

it.

Warmest wishes,

Barbara

Barbara A. , M.S., CCC-SLP

Executive Director/ Help Me Speak, LLC

<http://www.helpmespeak.com/> http://www.helpmespeak.com

(o) 410-442-9791 (f) 410-442-9783

2500 Wallington Way; Suite 103

Marriottsville, MD 21104

follow us on FaceBook:

http://www.facebook.com/pages/Marriottsville-MD/Help-Me-Speak-LLC/1046288520

32

Efusjon Energy Club <http://www.myefusjon.com/barbarataylor>

http://www.myefusjon.com/barbarataylor

call me before you join!

Lose weight w/ NutriVeda! http://www.barbarataylor.myzrii.com

From:

[mailto: ] On Behalf Of Barbara

Sent: Tuesday, January 12, 2010 2:57 PM

Subject: RE: [ ] Re: Update on Tanner on

Nutriiveda/interesting new study

AnnMarie,

Yes, it is safe for a 3.5yr old. Since NV was designed as a weight

management tool, it has not caused any of the kids to lose weight. All the

MDs who have reviewed it have said that is safe as well.

Here is the dosage by age: <4yrs= 1 scoop/day; 4-8yrs= 2 scoops/day; 9+yrs=

4 scoops/day

It is recommended to start with half the dose and then increase the next

week. Also it is recommended to split the full dose in half and give it

2x/day. So for 1 scoop, give 1/2 scoop in am and 1/2 scoop in afternoon or

pm.

As far as the energy, one of my clients' developmental pediatricians

recommends to start with 1/2 dose to make sure it doesn't affect your child

in that way. I haven't heard reports of 'too' much energy. I drink it and

notice that I have sufficient energy to get through the day w/o caffeine.

will have to report on how long it took until she saw changes in

Tanner. As I remember, only a week or 2.

Let me know what other questions you may have.

Warmest wishes,

Barbara

Barbara A. , M.S., CCC-SLP

Executive Director/ Help Me Speak, LLC

http://www.helpmespeak.com

(o) 410-442-9791 (f) 410-442-9783

2500 Wallington Way; Suite 103

Marriottsville, MD 21104

follow us on FaceBook:

http://www.facebook.com/pages/Marriottsville-MD/Help-Me-Speak-LLC/1046288520

32

Efusjon Energy Club http://www.myefusjon.com/barbarataylor

call me before you join!

Lose weight w/ NutriVeda! http://www.barbarataylor.myzrii.com

[ ] Re: Update on Tanner on

Nutriiveda/interesting new study

Hi Carol!

While Tanner had done well on the low dosage of vitamin e for about 2 years

-Tanner's had to be off all vitamin e since his massive regression on the

product called Speak which has mega dosages of vitamin E and K (may want to

read this to learn more why

http://www.facebook.com/topic.php?uid=115029735601

<http://www.facebook.com/topic.php?uid=115029735601 & topic=10637>

& topic=10637 )

For Tanner he no longer is on any supplements at all except 2 ProEFA and 1

ProEPA once a day and nutriiveda. I didn't think anything of Tanner being

on the 4 ProEFA and 2 ProEPA he was on for years...but once on the

Nutriiveda his speech SURGED- and not just speech but amount of speech,

clarity, complexity -and his surge was in academics and facial expressions.

His grades have gone up and he's not the only one. I have been posting

quite a few recent studies on Facebook and to our BigTent group about the

new research coming out showing the possible links between nutrition/amino

acids and protein to neurological function and repair.

Since your son is closer to Tanner's age and on/has been on the same

supplements -please check the nutriiveda out with his doctor and any friends

you have that are nutritionists etc. Everyone I have shown it to have been

very impressed with it and I was told if nothing else it's good nutrition

loaded with easily digestible protein and all the essential amino acids

etc.. The synergistic blend of ayurveda is something we are all learning

in this group but Sowmya from our group is from India and she says while

they may be new things to most of us -to her they are every day items used

in the diet. There are no known side effects, drug interactions, or

overdosage warnings on the product. In this group I do tell parents about

the vitamin a but from what I can gather the turmeric is very high in beta

carotene. Please call me with any questions 773 335 5135. It will be SO

cool to hear that like my son Tanner who's one of our older 'children' (and

of course Mel) that you see a

surge that brings your son up on all aspects. I mean I an honestly say

that Tanner is as close to " normal " now as whatever normal is. I don't

discredit the years of therapy and fish oils etc....but since the surges

were so rapid on the nutriiveda I do believe this metabolic product somehow

was so needed by him. He seems to be aware of it as well and asks for it.

I have my ADHD son Dakota on it for lunch every day now (he never wants to

eat lunch -and he's a horrible eater unlike Tanner) That was due to the 4

friend's kids - all teens -who went on the nutriiveda to lose a few pounds

and the side benefit is that all went to straight A students from B and C

students...well Josh had even more issues and jumped around a few schools

and is now " excelling " and straight As since on this. I find that too

strange to make it coincidence. The fish oils always sounded too good to be

true too -I'm sure like the fish oils there is a logical scientific

explanation as to what's going

on. Somehow I suspect if we start exploring some of the recent studies

we'll unlock more answers.

=====