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Drug Combo May Treat Brain Injury, Animal Study Suggests

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Executive Health September 24, 2010,

Drug Combo May Treat Brain Injury, Animal Study Suggests

Therapy seemed to improve rats' memory after trauma, but more research needed,

experts say

HealthDay/ScoutNews LLC

FRIDAY, Sept. 24 (HealthDay News) -- Drug therapy that combines a derivative of

the antibiotic tetracycline and a synthetic derivative of an amino acid may help

patients suffering from traumatic brain injury, a new study in animals suggests.

Rats treated with the therapy -- a combination of the antibiotic minocycline and

N-acetylcysteine -- showed marked improvement in reasoning and memory, according

to researchers from the State University of New York (SUNY) Downstate Medical

Center.

Currently, there are no drugs available that effectively treat traumatic brain

injury, or TBI. A number of single drugs have failed clinical trials, but U.S.

researchers decided to test various combinations of five drugs on rats with

experimental brain injuries.

" There is a great need for drugs to treat TBI. Perhaps the fastest way to get

treatments to the clinic is to combine drugs already known to be both safe and

effective, " study corresponding author J. Bergold, an associate professor

of physiology and pharmacology at SUNY Downstate Medical Center, said in a

center news release.

" The combination of minocycline and N-acetylcysteine showed a large, synergistic

improvement of cognition and memory after experimental traumatic brain injury.

We are continuing these studies to get this combination in a clinical trial, " he

said.

Each year in the United States, about 1.7 million people suffer a TBI, according

to background information in the news release. Most of these are concussions or

mild forms of brain injury, but more serious traumatic brain injuries cause a

considerable number of deaths and permanent cases of disability.

The research was recently published online in the journal PLoS One.

More information

The U.S. National Institute of Neurological Disorders and Stroke has more about

traumatic brain injury.

-- Preidt

SOURCE: SUNY Downstate Medical Center, news release, Sept. 17, 2010

HealthDay. All rights reserved.

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You can wait for them to finish up their synthetic drug version of what is found

in Mother Nature and see if there are no side effects over years...or you can

eat right.

If interested in the following I encourage you to read the original study from

December 2009 'With Amino Acid Diet, Mice Improve After Brain Injury'

http://www.sflorg.com/comm_center/medical/p974_99.html

" Neurology researchers have shown that feeding amino acids to brain-injured

animals restores their cognitive abilities and may set the stage for the first

effective treatment for cognitive impairments suffered by people with traumatic

brain injuries. "

I have on the theory page

" neurology researchers have shown that feeding amino acids to brain-injured

animals restores their cognitive abilities and may set the stage for the first

effective treatment for cognitive impairments suffered by people with traumatic

brain injuries. "

http://pursuitofresearch.org/science.html

So the choice is food or a drug? Pardon the pun...but no brainer! And why

don't they even mention the incredible results of just food which based on the

drug study are superior to the drug results? A quote from my Aunt Leona Dr.

Leona Wiener " Most follow the money, but search for the truth "

=====

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