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Re: Is NV a medication or just food?

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Hi Diane, thank you for your kind thoughts about my son . We are thrilled

with his progress on NV. As far as your curiosity about " discontinuation

syndrome " , that can and will occur if anyone, adults or children are taken off

of something that is essential to their bodies ie: citrus, water, AIR! Or, if

you stop all intake of fat or all intake of carbohydrates.

Ayurvedic medicine uses FOOD to heal the body. When you're sick and you eat

chicken soup it makes you feel better or when you have an upset stomach and you

eat tea and toast. Because the chicken soup and the tea and toast help you feel

better are they considered DRUGS?

You've brought this curiosity up in past posts and I'm wondering why. I feel

that you might be promoting fear in parents like myself who are always searching

for ways to help our children and if it's with something " natural " as opposed to

a drug, that's fantastic.

My son's Dr. approved the use of NV as did many other doctors. My son was on

Tegretol for 9 yrs. for his seizures which has a list of side effects including

liver damage.

NV has no side effects, everything in it is BALANCED. There is a member of this

group that is allergic to the sun and she has a physical reaction , does that

make the sun a drug? I am so happy to not have my son stuck for bloodwork every

3 months to see if he has liver damage. So if he can be on " Just Food " and not

have seizures, then so be it and that's what I will call it.

I include my phone # so that people in the group can call me with questions, I

welcome that. And I do not agree that we are misleading anyone saying a food is

a food as a food is a food. Until proven otherwise, NV is a food and Tegretol is

a medication and until you need a prescription for NV, it's not a medication.

But then again they have prescription fish oil now but I believe that it's still

not considered a drug it's considered prescription fish oil.

Wouldn't you rather use a food source rather than a medication that can damage

your body?I'm taken aback by your curiosity. Do you work for a pharmaceutical

company? Because if the FDA starts to consider food as " drugs " then oranges

could be $100 each and a canister of NV could be $500 a canister and it won't be

able to help a lot of kids at that cost if parents can't afford to buy it.

~~Dawn Falley 631-447-0615

> > >

> > > Hi everyone, so far so good, has been totally off his seizure

meds. 3 wks. now! But I wanted to let all know that last week we had 3 days of

h#ll, because I ran out of NV and he did not have any at all for 4 days. NOT

GOOD!!! He was having emotional meltdowns, he was super sensitive to any sounds,

like even if I was opening a bag of something, the crinkling was making him

cringe!He only got about 3 solid hrs. of sleep each night, because he kept

waking and the ceiling fan was scaring him. It was crazy and I felt sooo bad for

him. His speech definitely declined. Needless to say I ordered extra so this

does NOT happen again. As soon as he had 1 NV drink he started to get back to

himself.I just wanted to let everyone know what happened to us when we ran out.

If anyone would like to contact me my # is 631-447-0615 in New York.

> > >

> >

>

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But actually this is semantics -some call chicken soup " Jewish Penicillin " as a

joke. What about " comfort foods " and " food for thought " You may not know this

but those are expressions we picked up here in the West that have a basis in

ayurveda which is how we can use nutrition -Mother Nature- food to help the body

help itself. Ayurveda literally translates to the " science of life "

And questions like yours is why I have the story of the " magic orange " up on our

theory page

" I like to refer to the ignorance that surrounds nutrition's importance on

health, including neurological function, as the " magic orange " reaction. I'm

referring to scurvy and the impact a simple orange had on sailors years ago. Of

course the orange wasn't " magic " but if one is ignorant in the aspect of or

importance of the vitamin C in the orange they could look at the orange as

magically keeping a sailor alive. "

http://pursuitofresearch.org/science.html

And in addition I believe you may be missing a huge point ...Dawn's son is 14

and had been on seizure medication for NINE YEARS and JUST came off of them in

the past few days. Isn't there the possibility that is going through

discontinuation syndrome but not from NV but from the seizure meds? See I have

many PhDs in my family so even without my PhD with my IQ and background I think

like one -most don't that is the problem. Also -if you check areas of surges

http://pursuitofresearch.org/pursuit.html -as you can see noted typically

sensory improvements come in later -so 's strong sensory regression taken

off NV is not typical and being he's just off seizure meds that makes more sense

to me- it's logical. Speech regression, behavior regression are the two most

common regressions being taken off NV -and we see the same with fish oils when

we stop and they too are not drugs -they are essential fatty acids. Essential

(again) means the body needs it -can't produce it so needs to consume it.

Between NV and fish oils I believe we are providing our children with all the

essential nutrients their body's need to help the body help itself. It's

possible the NV balanced 's system to keep that stage of first being off

seizure medications under control...kind of like making sure you are hydrated to

lessen the affects of jet lag (and water isn't a drug either- and neither is

flying)

And as far as neurotransmitters there are other foods that contribute to

affecting the levels- the most well known is chocolate. So is chocolate a drug

or a candy or a food -see? I can even expand on your question if I wanted to

explore that. But I have enough information in that area to know that is not my

interest. My interest in understanding more about essential nutrients that

perhaps have been missing from our children's bodies.

And RDA is set because there are certain amount of various nutrients the human

body needs daily to function and maintain. If you don't get enough you have a

deficiency and you will have side effects from such deficiency. That does not

make nutrients drugs either.

But what makes ME curious if why you keep asking the same question here -clearly

if any one of us lay people or professionals knew one would answer you. Not

only that the doctors -the world renowned medical doctors behind NV

http://pursuitofresearch.org/advisors.html did not create NV for children, for

autism or apraxia, for therapeutic use in neurodevelopmental disorders...it was

created as a whole food product that used basic ayurvevda 101 principals so that

this one product could benefit any " dosha " (or anyone) and it will just support

good health, strengthen the metabolic system by providing essential nutrients

through whole food sources. Every single ingredient of NV is certified as a

food by the FDA and I verified that numerous times. In addition the product NV

is not only a clean food which is 100 percent natural and tested free of any

heavy metals, herbicides and pesticides it's 100 percent water soluble. There

were over 300 clinical studies on each of the foods that comprise NV that the

doctor's studied and the product is claimed by the company to have no known

overdose, side effects, or drug interactions.

And the most obvious....CLEARLY if any medical or research doctor in the world

knew that NV would have the amazing affects on our children and us too that it's

having in therapeutic ways for autism, apraxia, seizures etc....um....don't you

think there would be a number of companies producing the same product already

(I'm sure others will start NOW that I figured it out! Or try to anyway -good

luck to that!)

It may not make sense to you but clearly by pure mistake I discovered something

as just a parent that may lead to answers to help God only knows how many

children around the world. And last words from me....if a child's neurologist

or pediatrician approve this...if an MD from University of Kentucky who has his

PhD in neuropharmcology and Child & Adolescent Psychiatrist; Pediatrician;

Triple Board Graduate Vice Chair for Research, Department of Psychiatry

Researcher in Psychiatry and Anatomy Departments UK Outpatient Child &

Adolescent Psychiatrist Interests: Pervasive Developmental Disorders;

Developmental Pediatrics; Neuroscience Research....approves it as

" nutritionally sound and no reason a child can't take it " Perhaps ask someone

like him -or your child's doctor -or search online. But until there is research

we won't know how the foods are helping the body -but foods are healing to the

body...that does not make them drugs.

The following is about chocolate....a drug, a candy...or a food? (candy and

food I say -depending upon the type of chocolate)

Dr Le Fanu: Chocolate

Chocolate: finally, an excuse to indulge , says Dr Le Fanu.

By Dr Le Fanu

Published: 1:31PM BST 24 Aug 2010

Chocolate is reputedly the most comprehensively beneficial of all natural

products – certainly none is credited with being of value in so many, and for so

wide a range, of conditions.

The Aztecs started it with their physicians commending the pods of the

" chocolate tree " as a powerful fortifier prior to military (and sexual)

engagements and as a panacea for digestive ailments. Then, in the mid-18th

century, the great Swedish classifier of plants Carl Linnaeus named it Theobroma

cacao (literally " the food of the Gods " ) following which its medicinal

indications blossomed – for female complaints, promoting milk production in

nursing mothers, expelling kidney stones, as a sleeping draught and so on.

This might seem fanciful were it not that a couple of centuries later, when

chemists developed the techniques for analyzing the constituents of plants and

their products, they found chocolate to be among the most complex. It is now

known to contain a range of constituents of therapeutic relevance, including the

neurotransmitters dopamine and serotonin, the stimulant theobromine and the

famous antioxidants that protect the integrity of the lining of the arteries and

lower the blood pressure.

So, along with everything else, chocolate should also protect against heart

attacks and strokes, and there was much excitement last year with a study's

findings that regular chocolate eating increased the chances of surviving a

heart attack almost threefold.

For those with raised blood pressure the picture is not quite so clear. It

requires considerable quantities – a whole bar of 70 per cent chocolate a day –

to have the desired effect, which some might think is just " too much of a good

thing " .

Elsevier Ltd All rights reserved.

http://www.telegraph.co.uk/health/healthadvice/jameslefanu/7961898/Dr--Le-F\

anu-Chocolate.html

2-Phenylethylamine, a constituent of chocolate and wine, causes mitochondrial

complex-I inhibition, generation of hydroxyl radicals and depletion of striatal

biogenic amines leading to psycho-motor dysfunctions in Balb/c mice

T. Senguptaa and K.P. MohanakumarCorresponding Author Contact Information, a,

E-mail The Corresponding Author, E-mail The Corresponding Author

a Laboratory of Clinical and Experimental Neurosciences, Division of Cell

Biology and Physiology, Indian Institute of Chemical Biology (CSIR, Govt. of

India), 4, Raja S C Mullick Road, Jadavpur, Kolkata 700 032, India

Received 25 February 2010;

revised 29 June 2010;

accepted 24 July 2010.

Available online 4 August 2010.

Abstract

Behavioral and neurochemical effects of chronic administration of high doses of

2-phenylethylamine (PEA; 25–75 mg/kg, i.p. for up to 7 days) have been

investigated in Balb/c mice. Depression and anxiety, as demonstrated

respectively by increased floating time in forced swim test, and reduction in

number of entries and the time spent in the open arms in an elevated plus maze

were observed in these animals. General motor disabilities in terms of akinesia,

catalepsy and decreased swimming ability were also observed in these animals.

Acute and sub-acute administration of PEA caused significant, dose-dependent

depletion of striatal dopamine, and its metabolites levels. PEA caused

dose-dependent generation of hydroxyl radicals in vitro in Fenton's reaction in

test tubes, in isolated mitochondrial fraction, and in vivo in the striatum of

mice. A significant inhibition of NADH-ubiquinone oxidoreductase (complex-I; EC:

1.6.5.3) activity suggests the inhibition in oxidative phosphorylation in the

mitochondria resulting in hydroxyl radical generation. Nissl staining and TH

immnunohistochemistry in brain sections failed to show any morphological

aberrations in dopaminergic neurons or nerve terminals. Long-term

over-consumption of PEA containing food items could be a neurological risk

factor having significant pathological relevance to disease conditions such as

depression or motor dysfunction. However, per-oral administration of higher

doses of PEA (75–125 mg/kg; 7 days) failed to cause such overt neurochemical

effects in rats, which suggested safe consumption of food items rich in this

trace amine by normal population.

Keywords: Oxidative stress; NADH-unbiquinone oxidoreductase; Forced swim test;

Elevated plus maze; Anxiety; Depression; Parkinson's disease; Endogenous amines

contained in food; Chocolate; Wine

Article Outline

1.

Introduction

2.

Materials and methods

2.1. Animals

2.2. Chemicals and consumables

2.3. Experimental design

2.4. Analysis of behavioral parameters

2.4.1. Akinesia

2.4.2. Catalepsy

2.4.3. Swim test

2.4.4. Forced swim test

2.4.5. Elevated plus maze

2.4.6. PEA on in vitro generation of radical dotOH

2.4.7. PEA on ex vivo generation of radical dotOH

2.4.8. PEA on in vivo formation of radical dotOH

2.4.9. Mitochondrial complex-I assay

2.4.10. Brain histology and histochemistry

2.5. Statistics

3.

Results

3.1. General behavior

3.2. Motor behaviors

3.3. Psychometric assessment

3.4. Acute and sub-chronic effects of PEA on striatal biogenic amine

metabolism

3.5. Effects of PEA on the production of hydroxyl radical

3.6. Mitochondrial complex-I activity

3.7. Histology

3.8. Per-oral administration of PEA: effect on striatal biogenic amine

levels

4.

Discussion

Acknowledgements

References

http://www.sciencedirect.com/science?_ob=ArticleURL & _udi=B6T0B-50PCM43-2 & _user=1\

0 & _coverDate=08%2F04%2F2010 & _rdoc=1 & _fmt=high & _orig=search & _origin=search & _sort=\

d & _docanchor= & view=c & _searchStrId=1464866208 & _rerunOrigin=scholar.google & _acct=C\

000050221 & _version=1 & _urlVersion=0 & _userid=10 & md5=f8e407bdd87ab165f26527b8bcecad\

7b & searchtype=a

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