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,

I am so glad you told me about the folic acid. I had no idea. I will stop

taking it on Sunday nights when I take my MTX. I'm going to discuss this

with my doctors at Stanford next month. I can't believe they didn't tell me

about this problem.

I was sorry to hear all of your problems. I feel so badly for you and your

family. Keep me posted. You are in my prayers.

Take care and God bless you!

Amy

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Dear Amy, you are in my prayers always.

It has been great supporting each other this way for my morale.

My doc did say that if you needed to take the folic acid on the day of your

methotrexate that it would have to be timed carefully both before and after

needing a several hour window so as to not negate some of the action of the

methotrexate.

Interesting to note that the Arava , though it is the same class as

Methotrexate.. an antimetabolite, it doesn't cause mouth sores or bone marrow

suppression, so there is no need to use the Folic Acid!

Let me know how it goes with your appointment.

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Hi,

Good luck with the appointment! I just thought I'd mention a few things.

I've been through methotrexate therapy before and didn't tolerate it well.

It's taken me a while to find a therapy that works well and I'm almost in

complete remission, it just took time. Make sure your doctor has you biopsied

at least once a year (it doesn't hurt). If taking the pill form of MTX is too

expensive or if it upsets your stomach, MTX is available in an injectable

form that is cheaper and doesn't bother your stomach too much. I hope it's

the treatment for you and good luck again!

See ya in remission,

Chad

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  • 1 month later...
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--- Lee Ann Walter <SAWalter@...> wrote:

> From: " Lee Ann Walter " <SAWalter@...>

>

> Hi Annette!

> My Doc. plans on starting me at 7mg of MTX a week

> plus the folic

> acid. What is the folic acid for anyway?

Hi Lee Ann

Someone else may have a more specific reply but I

believe the folic acid simply helps with some of the

side effects of Methotrexate(MTX). I suffered from

mouth sores at first(and still do occasionally) but

went up to 3 folic acid tabs a day and it has helped a

lot. 7 mg of MTX is a very low dose, I'm on 17.5, so

hopefully you won't have any problems.

===

C McCullough

thelockhorns@...

_____________________________________________________________

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> Someone else may have a more specific reply but I

> believe the folic acid simply helps with some of the

> side effects of Methotrexate(MTX). I suffered from

> mouth sores at first(and still do occasionally) but

> went up to 3 folic acid tabs a day and it has helped a

> lot. 7 mg of MTX is a very low dose, I'm on 17.5, so

> hopefully you won't have any problems.

That what the doctors told me. Folic acid counters the side effects,

specifically the mouth sores/ulcers. I guess I have been lucky. I'm on 20mg

MTX per week and 5mg folic acid per day and have had no mouth ulcer

problems.

Cheers

Tony

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  • 1 month later...

--- Lee Ann Walter <SAWalter@...> wrote:

> Does any one know how much Folic acid a day is safe?

> I am on 1mg a day right now.

Hi Lee Ann

I'm on 3mg a day and have been told that up to 5mg is

okay.

===

C McCullough

thelockhorns@...

__________________________________________________

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At 09:16 PM 9/2/1999 -0400, you wrote:

>From: opaoma <opaoma@...>

>

>Lee Ann Walter wrote:

>>

>> Does any one know how much Folic acid a day is safe? I am on 1mg a

>> day right now.

>

>Lee Ann,

>I'm on 1 mg a day also.

>Marsha

FWIW, I was reading a blurb in the PDR about a particular prescription

vitamin that had 1 mg of folic acid. It had a warning in it that said,

" folic acid in doses above o.1 mg daily may obscure pernicious anemia in

that hematologic remission can occur while neurological manifestations

remain progressive. " (p. 3170 1999 PDR, Vicon Forte vitamin supplement.)

Beyond that, I don't know if there is any other danger to taking folic acid.

You might consider checking to see if taking it as " folate " is safer. I

don't know if it is, but many of the nutrients we need in small amounts

become toxic in larger amounts like Vit A and E, but are safe if taken in a

different form, such as betacarotene for Vit A. With betacarotene, the body

makes as much Vit A as it needs and discards the rest. I'm wondering if

there's another form of folic acid that is safe like that. Just a thought.

Kathy Fowkes

fowkes@...

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Lee Ann Walter wrote:

>

> Does any one know how much Folic acid a day is safe? I am on

1mg a

> day right now.

Lee Ann,

I'm on 1 mg a day also.

Marsha<<<

Does it depend on how much MTX you re taking? And isn't the

folic acid suppose to prevent the clod sores?

Lee Ann

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<!doctype html public " -//w3c//dtd html 4.0 transitional//en " >

<html>

I take 2.5 mg a day, and it is useful for both the mtx and my PCOS. & nbsp;

I don't take it on weekends, when I take my mtx.

<p>Janet

<br> & nbsp;

<br> & nbsp;</html>

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Lee Ann Walter wrote:

>

> Does any one know how much Folic acid a day is safe? I am on

1 mg a

> day right now.

>>Does it depend on how much MTX you re taking? And isn't the

folic acid suppose to prevent the clod sores?

Lee Ann<<

Marsha and Lee Ann, I recently questioned my RD on this subject. She

says if on a low dose of MTX, no more than 1 mg dly is needed. Anything more

would counteract the effect of MTX. Increase to 2 mg only if mouth sores are

present except on MTX day and day after. Catja

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I believe folic acid is one of those vitamins that is just excreted in

excess. our office puts certain pregnant moms on 4 mg per day with no

side effects.--Alysia

Lee Ann Walter wrote:

> Does any one know how much Folic acid a day is safe? I am on 1mg a

> day right now. I

>

>

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<!doctype html public " -//w3c//dtd html 4.0 transitional//en " >

<html>

" folic acid in doses above o.1 mg daily may obscure pernicious anemia in

<br>that hematologic remission can occur while neurological manifestations

<br>remain progressive. "

<p>Now can someone translate this for me??

<p>Janet</html>

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At 09:44 PM 9/3/1999 -0230, you wrote:

><!doctype html public " -//w3c//dtd html 4.0 transitional//en " >

><html>

> " folic acid in doses above o.1 mg daily may obscure pernicious anemia in

><br>that hematologic remission can occur while neurological manifestations

><br>remain progressive. "

><p>Now can someone translate this for me??

><p>Janet</html>

I had to really think about it too! :-) From what I can figure based on

root words and such, it looks like it's saying that if you have anemia, the

folic acid in doses of 1 mg or larger can mask the anemia when the usual

bloodtest is given to prove that it's there, making it look like the anemia

is better, when in fact it's still there and progressing, and still causing

problems. If there were any other contraindications for folic acid, I'm

sure it would have been listed, so unless you have anemia, I wouldn't worry

about it. :-)

Kathy Fowkes

fowkes@...

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It means that if you have pernicious anemia (which results in a low

hematocrit)

taking Folic Acid (which increases the hematocrit) would mask your illness.

Since we do not have the pernicious anemia we do not have to worry. We get a

boost from the folic acid because the side effect from Methotrexate is also

bone marrow supression - which results in

a lower red blood cell count and lower

hematocrit. Taking folic acid can keep us from getting anemic too!!! It

works really well for me personally!

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Catja848@... wrote:

>

> From: Catja848@...

>

>

>

> Lee Ann Walter wrote:

> >

> > Does any one know how much Folic acid a day is safe? I am on

> 1 mg a

> > day right now.

>

> >>Does it depend on how much MTX you re taking? And isn't the

> folic acid suppose to prevent the clod sores?

> Lee Ann<<

>

> Marsha and Lee Ann, I recently questioned my RD on this subject. She

> says if on a low dose of MTX, no more than 1 mg dly is needed. Anything more

> would counteract the effect of MTX. Increase to 2 mg only if mouth sores are

> present except on MTX day and day after. Catja

>

> ---------------------------

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  • 6 months later...
Guest guest

I always get an Upset Stomach if I DO NOT take my Folic Acid.

[ ] folic acid

From: PBias@...

Has anyone ever gotten upset stomach after taking folic acid? I never

seem to remember to take the folic acid but on the rare occassion that I

do I get an upset feeling. Maybe that is why I don't remember to take

it?

Pat B

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Guest guest

Dear ,

I also get an upset stomach if I forget to take my folic acid; at the

beginning, it happened to me quite often; now I think I got used to it.

I put the bottle on my kitchen table not to forget it next to the pepper

mill because I have to take it 3 times a week: Monday, Wednesday

and Friday. Sometimes I am asking myself : Which day is it

today, I get mix up, but it is quite an habit by now. I always see

the bottle and it really helps me.

Take care. Jocelyne

Harper wrote:

From: Harper <AHarper@...>

I always get an Upset Stomach if I DO NOT take my Folic

Acid.

[ ] folic acid

From: PBias@...

Has anyone ever gotten upset stomach after taking folic

acid? I never

seem to remember to take the folic acid but on the rare

occassion that I

do I get an upset feeling. Maybe that is why I don't

remember to take

it?

Pat B

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Enter:

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  • 3 months later...
Guest guest

Amy:

Tell me more, please. I am taking Folic Acid because my Dr. said I

needed to because I was taking MTX. I am injecting 10ml MTX weekly.

Please give me more info.

Thanks

Patty from Missouri

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Guest guest

Patty from Missouri,

I take two folic acids a day. They have helped so much with hair loss and

the scalp burning I have from the MTX. Now, I'm no expert, so I'm sure that

others can give you more scientific information, but it's changed my life.

Why we don't take folic acid on the MTX day has something to do with it

altering the effectiveness of the MTX. Others in the group advised me and

when I asked my doctors about it, they said they agreed with the group.

, the group founder is on vacation, but she has helped me more than I

can say.

Amy

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  • 2 months later...

In a message dated 9/5/00 2:17:21 AM Pacific Daylight Time,

egroups writes:

Hi all,

The folic acid is a methotrexate antidote so to speak. When you take it , it

stops the action of the methotrexate. That is why the doc usually says NOT to

take it on the day you take your Metho shot or pills. The Metho can help

tremendously with the mouth sores, fatigue, anemia and is well worth taking.

I have heard reported doses of anywhere from 1-5 mg per day for six days a

week from friends on the list over the years. It is pretty cheap, but somehow

you need a prescription anyway to get the 1 mg pills-the healthfood stores

have it around here-but in much smaller doses-so you would be taking three

pills to make up for 1 mg-pretty bad if you already take a few dozen pills a

day to deal with, so I asked for the prescription. It was and is not

reimbursable, but at least it is in the higher dose and is a teeny pill too.

I personally endorse taking it -- at least 1 mg six days a week for everyone

taking methotrexate right away! It can only help, and I am unaware of any

side effects from that small a dose, just good effects!

Join the Mailing List website for Psoriatic Arthritis by going to

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My folic acid is covered by my insurance. Also, my Rheum, explained to me the reasoning larger doses of Folic Acid is by prescription is because, it will mask certain illnesses in elderly people. Becky

[ ] Re:Folic Acid

It was and is not reimbursable, but at least it is in the higher dose and is a teeny pill too. I personally endorse taking it -- at least 1 mg six days a week for everyone taking methotrexate right away! It can only help, and I am unaware of any side effects from that small a dose, just good effects!

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, please let me know if you get an answer to your question regarding

the ratio of folic to B12. I currently take 10 mg/day of b-12

(hydroxycobalamin) IM injections and about 1 mg./day average of folic acid

but I have no idea what the proper ratio should be. Thanks, Steve Bullock

Folic Acid

>

> Is anyone using a good folic acid that they could recommend? And do you

know

> what the ratio should be for B12 to Folic Acid? I am taking B12

injections

> twice a week but I am not taking Folic Acid, I just found out that I most

> likely should be taking Folic Acid to balance out the B12. Thanks,

>

> This list is intended for patients to share personal experiences with each

other, not to give medical advice. If you are interested in any treatment

discussed here, please consult your doctor.

>

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