Effects of dietary coconut oil, butter and safflower oil on plasma lipids, lipoproteins and lathosterol levels.

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Hi All,

Nice last line:

" These data suggest that cholesterol synthesis is lower during diets rich in

coconut fat and safflower oil compared with

diets rich in butter and might be associated with lower production rates of

apoB-containing lipoproteins. "

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_uids=9\

756121 & dopt=Abstract

Eur J Clin Nutr 1998 Sep;52(9):650-4 Related Articles, Books, LinkOut

Effects of dietary coconut oil, butter and safflower oil on plasma lipids,

lipoproteins and lathosterol levels.

C, Sutherland W, Mann J, de Jong S, Chisholm A, Skeaff M.

Department of Human Nutrition, University of Otago, Dunedin, New Zealand.

OBJECTIVE:

The aim of this present study was to determine plasma levels of lathosterol,

lipids, lipoproteins and apolipoproteins

during diets rich in butter, coconut fat and safflower oil.

DESIGN:

The study consisted of sequential six week periods of diets rich in butter,

coconut fat then safflower oil and

measurements were made at baseline and at week 4 in each diet period.

SUBJECTS:

Forty-one healthy Pacific island Polynesians living in New Zealand participated

in the trial.

INTERVENTIONS:

Subjects were supplied with some foods rich in the test fats and were given

detailed dietary advice which was reinforced

regularly.

RESULTS:

Plasma lathosterol concentration (P < 0.001), the ratio plasma

lathosterol/cholesterol (P=0.04), low density lipoprotein

(LDL) cholesterol (P<0.001) and apoB (P<0.001) levels were significantly

different among the diets and were

significantly lower during coconut and safflower oil diets compared with butter

diets. Plasma total cholesterol, HDL

cholesterol and apoA-levels were also significantly (P< or =0.001) different

among the diets and were not significantly

different between buffer and coconut diets.

CONCLUSIONS:

These data suggest that cholesterol synthesis is lower during diets rich in

coconut fat and safflower oil compared with

diets rich in butter and might be associated with lower production rates of

apoB-containing lipoproteins.

PMID: 9756121 [PubMed - indexed for MEDLINE]

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