Re: microcephaly and nutriiveda

[Guest guest]

Hi Darlene -I'm on a Spring Break holiday till Wednesday but for sure want to

find out more for you. I just quickly found the following link which may

suggest that providing one with microcephaly all the essential amino acids is

shown to help (or that's how I'm reading it as again don't have much time to

look now. Deficient serine biosynthesis

http://www.springerlink.com/content/w0k6457g42593066 I will be in contact with

some of the medical doctors http://bit.ly/9eugoS behind the formulation and am

also curious if you have shared with your child's doctor. There is of course so

much more awareness today in traditional medical research as to the importance

of providing the appropriate nutrition to assist the body in helping itself. I

have a feeling based upon the vast differences of ages and diagnosis with surges

in days that this must be rooted in an essential nutrient that is for some

reason lacking or missing in today's diets worldwide.

Will post more later!

=====

[Guest guest]

- My daughter also has microcephaly so I would be very interested to

learn what your findings are.

Darlene- I did not even realize that there is a microcephaly support group-

I am off to learn more now. Thanks so much for inquiring about this.

Sam

_____

From:

[mailto: ] On Behalf Of kiddietalk

Sent: Sunday, April 11, 2010 12:31 PM

Subject: [ ] Re: microcephaly and nutriiveda

Hi Darlene -I'm on a Spring Break holiday till Wednesday but for sure want

to find out more for you. I just quickly found the following link which may

suggest that providing one with microcephaly all the essential amino acids

is shown to help (or that's how I'm reading it as again don't have much time

to look now. Deficient serine biosynthesis http://www.springer

<http://www.springerlink.com/content/w0k6457g42593066>

link.com/content/w0k6457g42593066 I will be in contact with some of the

medical doctors http://bit.ly/ <http://bit.ly/9eugoS> 9eugoS behind the

formulation and am also curious if you have shared with your child's doctor.

There is of course so much more awareness today in traditional medical

research as to the importance of providing the appropriate nutrition to

assist the body in helping itself. I have a feeling based upon the vast

differences of ages and diagnosis with surges in days that this must be

rooted in an essential nutrient that is for some reason lacking or missing

in today's diets worldwide.

Will post more later!

=====

[Guest guest]

Hi Darlene,

I think NV is being explored as a supplemental option for many types of issues

and conditions - so far, I have read about it being used to help with

speech/language disorders, ASD, Parkinson's, seizures, ADHD, metabolic

disorders, etc... I have tried it with my own son who has ASD. I know

will have much more information as to who has been using NV, but my only caution

is that you may not see the same results for your child as others who have other

conditions. NV certainly is a superior supplement in terms of it's " clean "

ingredients and stellar nutrition, but it's effects on each individual may vary.

For example, for children with speech disorders, some parents have reported

surges in speech; for parents of children with ADHD, some parents have noted

better attention and less hyperactivity; but the results may work better for

some conditions than others and for some individuals more than others. I guess

this is just my two cents... we had some gains with NV and some unexplainable

results while my son was on it - there might be other children with ASD who had

better results - there is just no guarantee. At this point, NV is being

explored by many - they are truly the " pioneers " to see where the true benefits

of the product lie - you could certainly offer yet another perspective by

trialling it with your daughter...

Tatyana

[ ] microcephaly and nutriiveda

Has anyone's children who have this condition been known to improve in any

developmental areas ie. speech, motor skills. My daughter has microcephaly and I

am considering using this supplement but I want to know from other parents and

[Guest guest]

My daughter is 3 and has microcephaly and she is working with specialist's at

our local Child Development Centre in Ontario, Canada. I am anxious to hear

what your doctor's have to say about any children with microcephaly they know

that might have benefited or may benefit from Nutriiveda. Once I get more info

from you and print off as much as possible from pursuit of research, I will

present it to my daughter's pediatrician, but I do expect that they will tell me

not to give it to her because where I live I find doctors are skeptical about

anything natural and reject the idea before becoming fully informed.

I feel they have written my daughter off as there is no cure for her condition

even though they are providing her much-needed therapy. We have specialists who

work with her, speech, occupational therapy, physical therapy, infant

development will be coming into the home so I know she can improve her skills as

I see her learn things all the time, but I so badly want her to talk. She is

completely non-verbal and from the microcephaly group this seems to be the case

of a lot of children, they just never talk. I am surprised when I hear of a

parent mentioning that their microcephalic child speaks. There is hope!

Also, if you have a doctor's name and number that I can provide to my daughter's

pediatrician and documented evidence, please let me know.

Thanks again !

>

> Hi Darlene -I'm on a Spring Break holiday till Wednesday but for sure want to

find out more for you. I just quickly found the following link which may

suggest that providing one with microcephaly all the essential amino acids is

shown to help (or that's how I'm reading it as again don't have much time to

look now. Deficient serine biosynthesis

http://www.springerlink.com/content/w0k6457g42593066 I will be in contact with

some of the medical doctors http://bit.ly/9eugoS behind the formulation and am

also curious if you have shared with your child's doctor. There is of course so

much more awareness today in traditional medical research as to the importance

of providing the appropriate nutrition to assist the body in helping itself. I

have a feeling based upon the vast differences of ages and diagnosis with surges

in days that this must be rooted in an essential nutrient that is for some

reason lacking or missing in today's diets worldwide.

>

> Will post more later!

>

> =====

>

[Guest guest]

Hi Darlene,

My daughter Evangelique with microcephaly will be turning 4 in July and we

are also located in Southern Ontario. What Child Development Centre do you

attend? My daughter said her first words Mama and Dada at the age of three

and now that she is going to speech three times a week more and more words

are emerging.

Hang in there.

Sam

_____

From:

[mailto: ] On Behalf Of darlene

Sent: Sunday, April 11, 2010 1:25 PM

Subject: [ ] Re: microcephaly and nutriiveda

My daughter is 3 and has microcephaly and she is working with specialist's

at our local Child Development Centre in Ontario, Canada. I am anxious to

hear what your doctor's have to say about any children with microcephaly

they know that might have benefited or may benefit from Nutriiveda. Once I

get more info from you and print off as much as possible from pursuit of

research, I will present it to my daughter's pediatrician, but I do expect

that they will tell me not to give it to her because whe re I live I find

doctors are skeptical about anything natural and reject the idea before

becoming fully informed.

I feel they have written my daughter off as there is no cure for her

condition even though they are providing her much-needed therapy. We have

specialists who work with her, speech, occupational therapy, physical

therapy, infant development will be coming into the home so I know she can

improve her skills as I see her learn things all the time, but I so badly

want her to talk. She is completely non-verbal and from the microcephaly

group this seems to be the case of a lot of children, they just never talk.

I am surprised when I hear of a parent mentioning that their microcephalic

child speaks. There is hope!

Also, if you have a doctor's name and number that I can provide to my

daughter's pediatrician and documented evidence, please let me know.

Thanks again !

>

> Hi Darlene -I'm on a Spring Break holiday till Wednesday but for sure want

to find out more for you. I just quickly found the following link which may

suggest that providing one with microcephaly all the essential amino acids

is shown to help (or that's how I'm reading it as again don't have much time

to look now. Deficient serine biosynthesis http://www.springer

<http://www.springerlink.com/content/w0k6457g42593066>

link.com/content/w0k6457g42593066 I will be in contact wit h some of the

medical doctors http://bit.ly/ <http://bit.ly/9eugoS> 9eugoS behind the

formulation and am also curious if you have shared with your child's doctor.

There is of course so much more awareness today in traditional medical

research as to the importance of providing the appropriate nutrition to

assist the body in helping itself. I have a feeling based upon the vast

differences of ages and diagnosis with surges in days that this must be

rooted in an essential nutrient that is for some reason lacking or missing

in today's diets worldwide.

>

> Will post more later!

>

> =====

>

[Guest guest]

We are in Kingston, Ontario, it is a great city, Southeastern Ontario. All the

specialists are great. I am glad to hear your daughter is saying words. It must

feel great to hear her call you dada.

Sam, what do you use for speech therapy, do you use the pecs (picture exchange

communication system) or was the therapist concentrating on having her make

sounds etc. My daughter won't repeat anything that I say to her, there is no

attempt to make a sound. Although, when she was a bit younger, she tried to

repeat E,I,E,I O from Old Mac but I tried this again later and

nothing.HELP!!!

The focus for my daughter is trying to get her to communicate and that is why

the focus on the PECS.

It is nice to see a fellow Ontarian in the group!

> >

> > Hi Darlene -I'm on a Spring Break holiday till Wednesday but for sure want

> to find out more for you. I just quickly found the following link which may

> suggest that providing one with microcephaly all the essential amino acids

> is shown to help (or that's how I'm reading it as again don't have much time

> to look now. Deficient serine biosynthesis http://www.springer

> <http://www.springerlink.com/content/w0k6457g42593066>

> link.com/content/w0k6457g42593066 I will be in contact wit h some of the

> medical doctors http://bit.ly/ <http://bit.ly/9eugoS> 9eugoS behind the

> formulation and am also curious if you have shared with your child's doctor.

> There is of course so much more awareness today in traditional medical

> research as to the importance of providing the appropriate nutrition to

> assist the body in helping itself. I have a feeling based upon the vast

> differences of ages and diagnosis with surges in days that this must be

> rooted in an essential nutrient that is for some reason lacking or missing

> in today's diets worldwide.

> >

> > Will post more later!

> >

> > =====

> >

[Guest guest]

Hi Sam,

Not sure where my response went to you earlier, but I did respond..

My daughter goes to the Kingston, Ontario Child Development Centre. The

specialists are very good there.

What methods is your speech therapist using in helping your daughter to talk.

We never had 3x times a week speech therapy. The most we get here is 1x a week

for 5-10 sessions and then several months of a break because of the long waiting

list of children who are in need of speech therapy. Where does your daughter

attend?

My daughter uses PECS the picture exchange communication system to help her

communicate, she hardly makes sounds. Did your daughter initally make alot of

sounds, did she try to repeat words that you said to her? My daughter likes to

blow raspberries and she drools alot I think because of lack of muscle tone in

her mouth.

Anyways, nice to see a fellow Ontarian here.

Darlene

> >

> > Hi Darlene -I'm on a Spring Break holiday till Wednesday but for sure want

> to find out more for you. I just quickly found the following link which may

> suggest that providing one with microcephaly all the essential amino acids

> is shown to help (or that's how I'm reading it as again don't have much time

> to look now. Deficient serine biosynthesis http://www.springer

> <http://www.springerlink.com/content/w0k6457g42593066>

> link.com/content/w0k6457g42593066 I will be in contact wit h some of the

> medical doctors http://bit.ly/ <http://bit.ly/9eugoS> 9eugoS behind the

> formulation and am also curious if you have shared with your child's doctor.

> There is of course so much more awareness today in traditional medical

> research as to the importance of providing the appropriate nutrition to

> assist the body in helping itself. I have a feeling based upon the vast

> differences of ages and diagnosis with surges in days that this must be

> rooted in an essential nutrient that is for some reason lacking or missing

> in today's diets worldwide.

> >

> > Will post more later!

> >

> > =====

> >

[Guest guest]

Any word from the doctor's on this topic . Sorry to push, I am just quite

anxious to see if my daughter would benefit from Nutriveda.

Hope you had a good holiday!

Darlene

>

> Has anyone's children who have this condition been known to improve in any

developmental areas ie. speech, motor skills. My daughter has microcephaly and I

am considering using this supplement but I want to know from other parents and

[Guest guest]

I was told I probably won't hear anything until next week. But in the meantime

I'm still snooping around. I keep reading that moms who have phenylketonuria

(PKU) have a 3 fold risk of having a child born with microcephaly..and PKU is

genetic. So probably first of course if anyone has PKU you wouldn't be able to

use nutriiveda. I'm sure pretty much all over at birth all babies are tested

for PKU however so you would know that.

If we look at the areas of improvement being reported for nutriiveda in

comparison to the symptoms of microcephaly

From the NIH site

http://www.ninds.nih.gov/disorders/microcephaly/microcephaly.htm

" Medications are often used to control seizures, hyperactivity, and

neuromuscular symptoms. "

We are hearing reports from those with children on nutriiveda of reductions of

seizures, improved focus for those diagnosed ADHD and neuromuscular symptoms

-that's kine of broad but we are seeing improvements in motor planning.

" Babies born with microcephaly will have a smaller than normal head that will

fail to grow as they progress through infancy. Depending on the severity of the

accompanying syndrome, children with microcephaly may have mental retardation,

delayed motor functions and speech, facial distortions, dwarfism or short

stature, hyperactivity, seizures, difficulties with coordination and balance,

and other brain or neurological abnormalities. Some children with microcephaly

will have normal intelligence and a head that will grow bigger, but they will

track below the normal growth curves for head circumference. "

Don't know about the smaller head size- we are getting reports of body growth

for height and muscle however but nutriiveda is still too new and yes as far as

I know you would be the first to try this. Coordination and balance -yes we are

hearing reports of surges in these areas.

To me as long as your child's doctor approves it as it's again just a very

healthy whole food and one rich in the essential amino acids that are linked in

research to neuro repair- why not try it?

Also outside of the amino acids -nutriiveda contains turmeric- and wait till you

read what I just found on how they are developing drugs that contain the

properties of turmeric -so why wait till they develop the drug which is man made

and use the real thing made by mother nature?

" The zebrafish model may prove a valuable tool with which to investigate the

impact of FA pathway failure on development as fancd2-deficient zebrafish

embryos develop similar defects to those found in children with FA, including

shortened body length, microcephaly (small head) and microphthalmia (small eyes)

[127]. The Xenopus model mostly constitutes a powerful tool with which to

investigate the regulation of the FA pathway in vitro through cell-free assay

systems using replicating egg extracts [124]. Such assays could also be utilized

for screening drugs that modulate the FA pathway.

Disease targets and ligands

The FA pathway is required for cellular resistance to DNA crosslinking agents,

including widely used anti-cancer drugs such as cisplatin, MMC and melphalan. As

such, inhibition of the FA pathway will lead to sensitization of tumor cells to

these drugs. Therefore, the FA pathway is an attractive target for developing

small molecule inhibitors that may be clinically useful as chemosensitizers in

the treatment of cancer. As described above, the FA pathway involves formation

of a multi-subunit protein complex harboring E3 ligase activity, several enzymes

(ubiquitin ligase and conjugating enzyme, deubiquitinating enzyme, kinase,

ATPase/DNA translocase and ATPase/helicase) and many protein–protein or

protein–DNA interactions. All of these components are potential targets for

small molecule inhibitors of the FA pathway.

Drug development targeting the FA pathway is still in the early stages, and

therefore not much information is available. A high-throughput cell-based

screening assay for small molecule inhibitors of the FA pathway has, however,

been developed by Alan D' (Dana-Farber Cancer Institute), Toshiyasu

Taniguchi (Fred Hutchinson Cancer Research Center) and their colleagues [128].

In this screen, inhibition of DNA damage-induced FANCD2 nuclear foci formation

was utilized as a readout. Continued screening is ongoing and a partial result

focusing on one inhibitor, curcumin (diferuloylmethane), has been published

[128]. Curcumin is a low-molecular-weight polyphenol derived from the rhizome

Curcuma longa and is the principal ingredient in the spice turmeric [129].

Curcumin inhibits FANCD2 monoubiquitylation and nuclear foci formation, although

its exact target in the FA pathway has not been identified [128]. However,

curcumin sensitizes an ovarian cancer cell line to cisplatin in an FA

pathway-dependent manner, suggesting that curcumin sensitization of cisplatin

mostly occurs through FA pathway inhibition [128]. In order to establish

curcumin as a useful cisplatin chemosensitizer, a detailed isobologram analysis

of combinations of curcumin with cisplatin, in vivo studies using mouse models,

and identification of the target of curcumin in the FA pathway are required. "

http://www.biomedcentral.com/1471-2091/8/S1/S10

As soon as I hear back from the docs promise to share!

=====