Moderate Intervention with Carotenoid-Rich Vegetable Products Reduces Lipid Peroxidation in Men

[Guest guest]

Hi All,

Another interesting full text paper showing tomato juice but not carrot juice or

spinach powder reduced LDL oxidation in

human males.

http://www.nutrition.org/cgi/content/full/130/9/2200

Moderate Intervention with Carotenoid-Rich Vegetable Products Reduces Lipid

Peroxidation in Men

ABSTRACT

Because of their antioxidant properties, carotenoids may have beneficial effects

in preventing cancer and cardiovascular

disease. However, in humans consuming carotenoid-rich vegetables, data

concerning the antioxidant effects of carotenoids

are rather scarce. A human intervention trial was conducted, therefore, to

determine whether a moderately increased

consumption of carotenoid-rich vegetables would influence the antioxidant status

in 23 healthy men. This short-term

feeding study lasted 8 wk during which the men consumed a low carotenoid diet. A

2-wk low carotenoid period was followed

by daily consumption of 330 mL tomato juice, then by 330 mL carrot juice and

then by 10 g of spinach powder, each for 2

wk. Antioxidant status [water-soluble antioxidants in serum, ferric reducing

ability of plasma (FRAP) and antioxidant

enzyme activities] and lipid peroxidation (plasma malondialdehyde and ex vivo

oxidation of LDL) were determined. In a

subgroup of 10 men, lipoprotein carotenoids were measured. The consumption of

carotenoid-rich vegetables significantly

increased selected carotenoids in lipoproteins but had only minor effects on

their relative distribution pattern.

Tomato juice consumption reduced plasma thiobarbituric acid reactive substances

(TBARS) by 12% (P < 0.05) and

lipoprotein oxidizability in terms of an increased lag time (18%, P < 0.05).

Carrot juice and spinach powder had no effect on lipid peroxidation.

Water-soluble antioxidants, FRAP, glutathione peroxidase and reductase

activities did not change during any study

period. In evaluating the low carotenoid diet, we conclude that the additional

consumption of carotenoid-rich vegetable

products enhanced lipoprotein carotenoid concentrations, but only tomato juice

reduced LDL oxidation in healthy men.

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Good health & long life,

Greg ,

http://optimalhealth.cia.com.au