Re: Oxygen as Cause of Chromosome Damage

[Guest guest]

Great story and post.

Puts me in mind of an old sci-fi story where a legislature passed a

bill setting pi = 3 (for the non-techies out there who don't remember

this from school, pi = 3.14159.... and relates the circumference and

radius of a circle and continues forever in the decimal places

without repeating)

I'll now expect to hear a legislator call for the EPA to regulate

oxygen levels. :-J

Iris

--- In @y..., " Greg " <gowatson@s...>

wrote:

> Hi All,

>

> Too bad the paper didn't suggest caloric restriction and eating

high ORAC foods as proven ways to reduce undesirable

> free radical activity.

>

> http://www.lef.org/news/aging/2002/03/12/eng-ascribe/eng-

ascribe_160706_208_782600020058.html

> USC Researchers Define Role of Protein, Identify Oxygen as Cause of

Chromosome Damage

> AScribe Newswire

> University of Southern California

> March 12, 2002

>

> LOS ANGELES, March 12 (AScribe Newswire) --

> Pinpointing oxygen as the cause of routine chromosome damage and

defining the role of a key protein in the repair of

> that damage are the subjects of two recently published papers from

the laboratory of USC/Norris Comprehensive Cancer

> Center pathologist Lieber, the Rita and Polusky

Chair in Basic Cancer Research at the Keck School of

> Medicine.

< snip >

> The solution? ly, said Lieber, there may be none. " Oxygen -

can't live with it, can't live without it, " he

> commented. " We need it to survive, but ultimately, it's also

probably what kills us. "

>

> Citation: Yunmei Ma, Ulrich Pannicke, Klaus Schwarz and R.

Lieber, " Hairpin Opening and Overhand Processing by

> an Artemis/DNA-Dependent Protein Kinase Complex in Nonhomologous

End Joining and V(D)J Recombination. " Cell Immediate

> Early Publication, March 1, 2002, http://www.cell.com

>

> Citation: Zarir E. Karanjawala, Niamh , R. Hinton, Chih-

Lin Hsieh and R. Lieber, " Oxygen Metabolism

> Causes Chromosome Breaks and Is Associated with the Neuronal

Apoptosis Observed in DNA Double-Strand Break Repair

> Mutants. " Current Biology, Vol. 12, pp. 397-402, March 5, 2002.

[Guest guest]

Actually, that wasn't a Sci-Fi story.

The Pi=3 thing really happened here in the U.S.

----- Original Message -----

From: " oc9 " <ibap@...>

< >

Sent: Wednesday, March 20, 2002 10:20 AM

Subject: [ ] Re: Oxygen as Cause of Chromosome Damage

> Great story and post.

>

> Puts me in mind of an old sci-fi story where a legislature passed a

> bill setting pi = 3 (for the non-techies out there who don't remember

> this from school, pi = 3.14159.... and relates the circumference and

> radius of a circle and continues forever in the decimal places

> without repeating)

>

> I'll now expect to hear a legislator call for the EPA to regulate

> oxygen levels. :-J

>

> Iris

>

>

> > Hi All,

> >

> > Too bad the paper didn't suggest caloric restriction and eating

> high ORAC foods as proven ways to reduce undesirable

> > free radical activity.

> >

> > http://www.lef.org/news/aging/2002/03/12/eng-ascribe/eng-

> ascribe_160706_208_782600020058.html

> > USC Researchers Define Role of Protein, Identify Oxygen as Cause of

> Chromosome Damage

> > AScribe Newswire

> > University of Southern California

> > March 12, 2002

> >

> > LOS ANGELES, March 12 (AScribe Newswire) --

> > Pinpointing oxygen as the cause of routine chromosome damage and

> defining the role of a key protein in the repair of

> > that damage are the subjects of two recently published papers from

> the laboratory of USC/Norris Comprehensive Cancer

> > Center pathologist Lieber, the Rita and Polusky

> Chair in Basic Cancer Research at the Keck School of

> > Medicine.

> < snip >

> > The solution? ly, said Lieber, there may be none. " Oxygen -

> can't live with it, can't live without it, " he

> > commented. " We need it to survive, but ultimately, it's also

> probably what kills us. "

> >

> > Citation: Yunmei Ma, Ulrich Pannicke, Klaus Schwarz and R.

> Lieber, " Hairpin Opening and Overhand Processing by

> > an Artemis/DNA-Dependent Protein Kinase Complex in Nonhomologous

> End Joining and V(D)J Recombination. " Cell Immediate

> > Early Publication, March 1, 2002, http://www.cell.com

> >

> > Citation: Zarir E. Karanjawala, Niamh , R. Hinton, Chih-

> Lin Hsieh and R. Lieber, " Oxygen Metabolism

> > Causes Chromosome Breaks and Is Associated with the Neuronal

> Apoptosis Observed in DNA Double-Strand Break Repair

> > Mutants. " Current Biology, Vol. 12, pp. 397-402, March 5, 2002.

>

>

>

>

>

[Guest guest]

Yes, ideed. In Indiana they tried to set pi=4, 3.2, or 3.23:

http://www.straightdope.com/classics/a3_341.html

>From: " " <defiler@...>

>Reply-

>< >

>Subject: Re: [ ] Re: Oxygen as Cause of Chromosome

>Damage

>Date: Wed, 20 Mar 2002 12:15:41 -0500

>

>Actually, that wasn't a Sci-Fi story.

>The Pi=3 thing really happened here in the U.S.

>

>----- Original Message -----

>From: " oc9 " <ibap@...>

>< >

>Sent: Wednesday, March 20, 2002 10:20 AM

>Subject: [ ] Re: Oxygen as Cause of Chromosome Damage

>

>

> > Great story and post.

> >

> > Puts me in mind of an old sci-fi story where a legislature passed a

> > bill setting pi = 3 (for the non-techies out there who don't remember

> > this from school, pi = 3.14159.... and relates the circumference and

> > radius of a circle and continues forever in the decimal places

> > without repeating)

> >

> > I'll now expect to hear a legislator call for the EPA to regulate

> > oxygen levels. :-J

> >

> > Iris

> >

> >

> > > Hi All,

> > >

> > > Too bad the paper didn't suggest caloric restriction and eating

> > high ORAC foods as proven ways to reduce undesirable

> > > free radical activity.

> > >

> > > http://www.lef.org/news/aging/2002/03/12/eng-ascribe/eng-

> > ascribe_160706_208_782600020058.html

> > > USC Researchers Define Role of Protein, Identify Oxygen as Cause of

> > Chromosome Damage

> > > AScribe Newswire

> > > University of Southern California

> > > March 12, 2002

> > >

> > > LOS ANGELES, March 12 (AScribe Newswire) --

> > > Pinpointing oxygen as the cause of routine chromosome damage and

> > defining the role of a key protein in the repair of

> > > that damage are the subjects of two recently published papers from

> > the laboratory of USC/Norris Comprehensive Cancer

> > > Center pathologist Lieber, the Rita and Polusky

> > Chair in Basic Cancer Research at the Keck School of

> > > Medicine.

> > < snip >

> > > The solution? ly, said Lieber, there may be none. " Oxygen -

> > can't live with it, can't live without it, " he

> > > commented. " We need it to survive, but ultimately, it's also

> > probably what kills us. "

> > >

> > > Citation: Yunmei Ma, Ulrich Pannicke, Klaus Schwarz and R.

> > Lieber, " Hairpin Opening and Overhand Processing by

> > > an Artemis/DNA-Dependent Protein Kinase Complex in Nonhomologous

> > End Joining and V(D)J Recombination. " Cell Immediate

> > > Early Publication, March 1, 2002, http://www.cell.com

> > >

> > > Citation: Zarir E. Karanjawala, Niamh , R. Hinton, Chih-

> > Lin Hsieh and R. Lieber, " Oxygen Metabolism

> > > Causes Chromosome Breaks and Is Associated with the Neuronal

> > Apoptosis Observed in DNA Double-Strand Break Repair

> > > Mutants. " Current Biology, Vol. 12, pp. 397-402, March 5, 2002.

> >

> >

> >

> >

> >

[Guest guest]

remeber when i said calories are a bit like oxygen, look at this post.

The interesting thing is when you cut caslories you cut down on your need

for oxygen. Hmmmm...

----- Original Message -----

From: oc9 <ibap@...>

< >

Sent: Wednesday, March 20, 2002 7:20 AM

Subject: [ ] Re: Oxygen as Cause of Chromosome Damage

> Great story and post.

>

> Puts me in mind of an old sci-fi story where a legislature passed a

> bill setting pi = 3 (for the non-techies out there who don't remember

> this from school, pi = 3.14159.... and relates the circumference and

> radius of a circle and continues forever in the decimal places

> without repeating)

>

> I'll now expect to hear a legislator call for the EPA to regulate

> oxygen levels. :-J

>

> Iris

>

>

> > Hi All,

> >

> > Too bad the paper didn't suggest caloric restriction and eating

> high ORAC foods as proven ways to reduce undesirable

> > free radical activity.

> >

> > http://www.lef.org/news/aging/2002/03/12/eng-ascribe/eng-

> ascribe_160706_208_782600020058.html

> > USC Researchers Define Role of Protein, Identify Oxygen as Cause of

> Chromosome Damage

> > AScribe Newswire

> > University of Southern California

> > March 12, 2002

> >

> > LOS ANGELES, March 12 (AScribe Newswire) --

> > Pinpointing oxygen as the cause of routine chromosome damage and

> defining the role of a key protein in the repair of

> > that damage are the subjects of two recently published papers from

> the laboratory of USC/Norris Comprehensive Cancer

> > Center pathologist Lieber, the Rita and Polusky

> Chair in Basic Cancer Research at the Keck School of

> > Medicine.

> < snip >

> > The solution? ly, said Lieber, there may be none. " Oxygen -

> can't live with it, can't live without it, " he

> > commented. " We need it to survive, but ultimately, it's also

> probably what kills us. "

> >

> > Citation: Yunmei Ma, Ulrich Pannicke, Klaus Schwarz and R.

> Lieber, " Hairpin Opening and Overhand Processing by

> > an Artemis/DNA-Dependent Protein Kinase Complex in Nonhomologous

> End Joining and V(D)J Recombination. " Cell Immediate

> > Early Publication, March 1, 2002, http://www.cell.com

> >

> > Citation: Zarir E. Karanjawala, Niamh , R. Hinton, Chih-

> Lin Hsieh and R. Lieber, " Oxygen Metabolism

> > Causes Chromosome Breaks and Is Associated with the Neuronal

> Apoptosis Observed in DNA Double-Strand Break Repair

> > Mutants. " Current Biology, Vol. 12, pp. 397-402, March 5, 2002.

>

>

>

>

>