Re: Valentina/Anne: doubling up first dose

[Guest guest]

I double both ALA and DMSA if I use both.

I am not sure what " working it out " means... Are you asking about the math

behind the reason? If yes, then let's say your dose is 10mg of ALA (or

whatever chelator you use).

You start by taking a double dose - 20mg; after 3 hours you will have 10 mg

left in your system. Take a dose and now you will have 20 mg in your system.

After another 3 hours you will have 10 mg left in your system. Take another

dose and you will have 20 mg... and so on. So the levels oscillate between

10 -> 20 mg.

If you start by taking one dose, the math would be like this:

10 mg - after 3 hours -> 5 mg in your system

take another dose 5 + 10 = 15 mg - after 3 hours -> 7.5 mg in your system

take another dose 7.5 + 10 = 17.5 mg - after 3 hours -> 8.75 mg in your

system

take another dose 8.75 + 10 = 18.75 mg - after 3 hours -> 9.37 mg in your

system

take another dose 9.37 + 10 = 19.37 mg - after 3 hours -> 9.68 mg in your

system

take another dose 9.68 + 10 = 19.68 mg - after 3 hours -> 9.84 mg in your

system

take another dose 9.84 + 10 = 19.84 mg - after 3 hours -> 9.92 mg in your

system

So it would take about 3-4 doses until the levels " stabilize " and oscillate

between 10 -> 20 mg with every dose.

Was this what you were asking for?

Valentina

> A week or two ago Valentina metioned that she always doubles the first

> dose of ALA to get the blood levels up faster, then Anne somehow

> figured out how to check this and confirmed that it would work. I've

> been wondering about trying this ever since, and because I'm a visual

> learner I'm having a hard time working it out in my head. Anne, would

> you somehow be able to share what you did to work this out? Also,

> would this also be safe if done with DMSA/ALA on a three hour

> schedule? I can't see why it wouldn't if it's safe with ALA, but I

> can't trust my reasoning.

>

[Guest guest]

Yes, Valentina, this is exactly what I was asking for. Thank you!

René

> Was this what you were asking for?

>

>

> Valentina

[Guest guest]

Valentia,

Thank you for that analysis !

I glanced at this topic a while back and was thinking it over and this is

exactly what I came up with in my mind.

Your explanation makes it very clear.

I will now start doing the same thing.

Regards,

Neil

_____

From: [mailto: ]

On Behalf Of joshisims

Sent: Friday, March 17, 2006 11:50 PM

Subject: [ ] Re: Valentina/Anne: doubling up first dose

Yes, Valentina, this is exactly what I was asking for. Thank you!

René

> Was this what you were asking for?

>

>

> Valentina

=======================================================

[Guest guest]

This is very interesting. Thank you for bringing this up. It does

seem like a nice way to keep the levels as steady as possible in the

body.

Beti

>

> I double both ALA and DMSA if I use both.

> I am not sure what " working it out " means... Are you asking about

the math

> behind the reason? If yes, then let's say your dose is 10mg of ALA

(or

> whatever chelator you use).

>

> You start by taking a double dose - 20mg; after 3 hours you will

have 10 mg

> left in your system. Take a dose and now you will have 20 mg in

your system.

> After another 3 hours you will have 10 mg left in your system.

Take another

> dose and you will have 20 mg... and so on. So the levels oscillate

between

> 10 -> 20 mg.

>

> If you start by taking one dose, the math would be like this:

> 10 mg - after 3 hours -> 5 mg in your system

> take another dose 5 + 10 = 15 mg - after 3 hours -> 7.5 mg in your

system

> take another dose 7.5 + 10 = 17.5 mg - after 3 hours -> 8.75 mg in

your

> system

> take another dose 8.75 + 10 = 18.75 mg - after 3 hours -> 9.37 mg

in your

> system

> take another dose 9.37 + 10 = 19.37 mg - after 3 hours -> 9.68 mg

in your

> system

> take another dose 9.68 + 10 = 19.68 mg - after 3 hours -> 9.84 mg

in your

> system

> take another dose 9.84 + 10 = 19.84 mg - after 3 hours -> 9.92 mg

in your

> system

> So it would take about 3-4 doses until the levels " stabilize " and

oscillate

> between 10 -> 20 mg with every dose.

>

> Was this what you were asking for?

>

>

> Valentina

>

>

>

>

>

>

> > A week or two ago Valentina metioned that she always doubles the

first

> > dose of ALA to get the blood levels up faster, then Anne somehow

> > figured out how to check this and confirmed that it would work.

I've

> > been wondering about trying this ever since, and because I'm a

visual

> > learner I'm having a hard time working it out in my head. Anne,

would

> > you somehow be able to share what you did to work this out?

Also,

> > would this also be safe if done with DMSA/ALA on a three hour

> > schedule? I can't see why it wouldn't if it's safe with ALA,

but I

> > can't trust my reasoning.

> >

>