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Carbohydrates, protein, animal fat, vitamins folate and B12 and centenarians

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Hi All, Regarding carbohydrates, protein, animal fat, vitamins folate and

B12 and centenarians:

For breast cancer avoidance, carbohydrates were good but bad were total fat

and animal protein in:

“prospective …. 5.5 yr of follow-up…. 3,367 postmenopausal members; 214

controls …. adjusted odds ratios for the highest tertile of intake vs. the

lowest were 3.47 …. for total fat, 3.78 ….for animal protein, and 0.42 ….

for total carbohydrates. These findings indicate a significant positive

association between total fat and animal protein and risk of breast cancer

and an inverse association with carbohydrates and constitute new evidence

for a role of diet in the etiology of breast cancer.”

PMID: 12235640 [PubMed - in process]

While PMID: 12208894 [PubMed - in process] found high glycemic load and

fructose were risks (relative risk 1.53, not significant) for pancreatic

cancers, especially in the overweight (2.7, significant) and low exercising

(3.2, significant) persons, high carbohydrates and sucrose were not risks.

The PDF is available.

The recommended daily allowance for vitamin B12 is about 2 microgram but

PMID: 12028259 [PubMed - indexed for MEDLINE] said 10 had no effect on serum

vitamin B12 in the elderly having low or borderline levels. 5 mg and

cobalamin (vitamin B12) 400 micrograms daily or placebo were used in PMID:

12204509 [PubMed - indexed for MEDLINE] to improve heart status. It seems

that much more than normal levels were needed.

There was a PDF available review in Age and Aging September of a book on

homocysteine and folate saying 2 pounds of broccoli should give enough. It

is more than enough broccoli for my dinner plate, I would say.

Centenarians ran a gauntlet of diseases in early life that we have not

encountered and I feel that their genetics may be optimal for their unique

disease exposures.

Cheers, Al.

Alan Pater, Ph.D.; Faculty of Medicine; Memorial University; St. 's, NF

A1B 3V6 Canada; Tel. No.: (709) 777-6488; Fax No.: (709) 777-7010; email:

apater@...

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