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Hi All,

Change in blood pressure in late life, low pressure earlier and survival is

discussed in the below article titled “Change in Blood Pressure in the Age

Interval 70-90”.

It says it seems that low pressure, which CRONies have, is good. However,

later in life, an increase is desirable. To me it fits in with the general

idea that we need to moderate CR in very late life. As with the calories,

so the effect it has on blood pressure, maybe.

This latest issue of the journal was not in Medline yet.

Cheers, Al.

Change in Blood Pressure in the Age Interval 70-90. Late Blood Pressure Peak

Related to Longer Survival

Author(s): Bodil Lernfelt; Alvar Svanborg

Blood Pressure, 4, 206-212

“…. systolic (SBP) and diastolic blood pressure (DBP) … in two

representative population samples (n = 973 and n = 1036). …. In the total

population sample, SBP increased up to age 75 and declined thereafter. In

survivors up to 90, SBP increased up to age 79 and decreased thereafter. DBP

decreased after 70. Up to age 82, women had higher SBP and DBP than men. Low

SBP at 70 and 75 were correlated to longer survival in both sexes. The

relation between blood pressure peak and survival up to age 90 was analysed

in 424 men and 640 women, all examined at 70, 75 and 79 years. Twenty-six

per cent of men and 44% of women with the highest SBP at 79 survived up to

90 years compared with 15% of men and 31% of women with the highest SBP at

70. SBP and DBP at age 90 were higher in survivors up to age 93 compared

with non-survivors. incipal conclusion: Low blood pressure at 70 and late

SBP peak were related to longer survival after age 79.”

Alan Pater, Ph.D.; Faculty of Medicine; Memorial University; St. 's, NF

A1B 3V6 Canada; Tel. No.: (709) 777-6488; Fax No.: (709) 777-7010; email:

apater@...