Yo-yo CR better than CR for cancer

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Hi All,

This paper did seem to be a perfectly matched diets paper in that the mice

got all essentials every day but distributed only calories differently. It

may be much better than every other day diets or fasting in this way. Get

all essential supplements, proteins and fats each day.

Cheers, Al.

“Ad libitum-fed mice (n = 30) were fed American Institute of Nutrition

(AIN)-93M diet. Beginning at 10 weeks of age, weight-cycled mice (n = 30)

were fed an AIN-93 modified diet (2-fold increase in protein, fat, vitamin,

and mineral contents) at 50% of ad libitum for 3-week intervals followed by

3-week intervals of ad libitum feeding using AIN-93M diet. Pair-fed mice (n

= 33), were fed a 2:1 mixture of AIN-93M:AIN-93 modified diets to match the

caloric intake of weight-cycled mice for each 6-week age-matched caloric

restriction/refeeding interval. ...”

PMID: 12223427 [PubMed - as supplied by publisher]

Alan Pater, Ph.D.; Faculty of Medicine; Memorial University; St. 's, NF

A1B 3V6 Canada; Tel. No.: (709) 777-6488; Fax No.: (709) 777-7010; email:

apater@...