RE: To Mark and others, about dosage and fibromyalgia

[Guest guest]

Wow, thanks for all the posts answering my testomony about LDN and

how it helps me with fibromyalgia.

Mark, if the prescription was writen for 4.5 mg please have your mom

go back to the pharmacy and get the proper prescription. It doesn't

hurt to start on that amount, but more is useless. If throughout the

first month your mom has a feeling of being hyper or jittery have the

dose decreased. It isn't a good idea to try to lower the dose

herself, although the prescription " should work " from 4.5 to as low a

dose as 1.75 mg. I would rather know what amount I was getting.

Next, I noticed the first three nights I didn't sleep as well on 4.5

mg and for fibromyalgia deep sleep is the utmost important thing.

Even though I didn't get the deep sleep those three nights I didn't

ache nearly as much the next day. A plus!!

By day 3 the depression from chronic pain sort of went away. I quit

taking trazodone, an anti-depressant at night by night 4 without any

side effects of withdrawal. In fact, I didn't want anything but the

Restoril which I till take at night for the Stage IV deep sleep.

By the end of 7 nights on LDN I woke up without pain and stiffness.

To this day I feel so much better in the mornings. I think I am

getting the deep sleep because I feel more refreshed than I used to.

LDN does not help with acute pain, like when I sprained my ankle.

When that happened I also fell down. So the ankle pain was acute and

as bad as normal pain would be. I also fell down and that in itself

would have caused a whole body pain flare, but with LDN my total body

pain never really happened. I was a little sore, but NOT in an acute

flare. My ankle is taking the usual time to heal.

Hopefully your mom should feel some improvement within a week. It

may not be very apparent at first. I read that we should give it at

least three months for the body to get regulated on this drug.

In my case it was within 3 days to notice good improvement.

Another sign that it is helping is that she should experience more

energy. That chronic fatigue should let up.

Since starting the LDN I have been able to stop taking three drugs,

Neurontin, Trazodone, and the horrible Ultram. The Ultram caused

highs and lows and pain was worse when it wore off. I had to stop

taking Ultram 2 1/2 weeks before starting Naltrexone.

Be sure that your mom is not on any opioids, such as Tylenol with

codeine or Ultram. All of this must be out of her system before

starting LDN.

There is the slow-release LDN! Contrary to what others may say. My

Pharmacist found out that there is....so make sure you have the fast-

acting prescription. Slow-release is not for any of us in low doses!!

Our body makes enkephalin and dynorphin, natural endorphins. LDN is

a booster to these natural hormones which are natural pain PERCEPTION

blockers. This is really hard to describe if you don't understand

the body's chemisty and the physiological aspects as well as anatomy,

but trust that it works in our brains to put pain in it's proper

perspecive. It is known that with fibromyalgia, the sufferer can

experience many things such as noise as pain. Yes, we think noise

causes pain!! (Our brain pattern perception to some stimuli.) It is

hard to put that down on paper without sounding " nuts. "

The LDN should be taken between 9 p.m. and 3 a.m. It is in the deep

sleep in which our bodies should be doing the job of building and

repairing, and restoring our muscle tears from daily activities, and

also build up our normal endorphins. People with fibromyalgia have

trouble in that area, we don't build and repair normally.

I cannot say how it is with MS and other diseases because my resaerch

has been mostly with my own illness and I have 20 years of experience

looking for RELIEF.

My jitters (a feeling of hyperactivity) kept up all month until I

changed to 3 mg. I can go up or down but I have decided to stay at 3

mg for the next few months. On the 4.5 I took long walks which eased

that up but I didn't like the feeling when I wasn't moving around.

I hope this helps your mom as much as it is helping me. The LDN Web

site states that people with primary fibromyalgia should get 95% pain

relief. If some have chronic fatigue syndrome it is only 50%

relief. If someone has both--I don't know what the percentage may

be. But to me 50% is better than none. I would say I am getting

about 60 to 90 percent of pain relief.

I still get muscle spasms in my neck and shoulders from doing too

much at times. It is O.K. to take a muscle relaxant and something

like Baclofen or aspirin on LDN. Stay way from morphines, codeine,

etc. Endorphins are made in the hypothalamus and a few other parts

of the brain and acts on opioid receptors, too complicated to state

here.

Let us know if this is helping your mother. I believe the main thing

is: Don't give up.