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Dosage and Inttermittant therapy

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It appears clear that some people are starting addressing problems to

an high dosage of LDN of 4.5 mg.

I had a prescription from a doctor here in UK and he is suggesting to

start with 3 mg at least for a month before upgrading dosage. He is

also highlighting the fact that upgrading to an higher dosage should

be closely monitored. Furthermore, my UK doctor tells me that taking

3 mg of LDN doesn't create problems for that initial month, however,

when moving to 4.5 he is advising to undertake an intermittant

therapy of 2 weeks on LDN followed by 3 days off in a cycle. He does

inform me in the same documentation that Dr. Bihary does not equally

advise this intermittent therapy.

I am starting to suspect that upgrading the dose it is not a must and

it might be person dependent....

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I'm 5'4, 130 lbs, and have had lots of allergy related MS exacerbations over

the years (just got DX last summer). I also used to have a very fast

metabolism and work mainly 12-8AM (ET). I figured if someone 5'8 and taller,

150 lbs and heavier, and a slower metabolism, figuring on averages, are all

taking 4.5 mg, then 3 should work well for me.

I've been taking LDN between midnight and 2am since 4/17. The week of 4/21 was

the busiest, most physically active, week I've had a long long while. I don't

know how I would have handled the week had I not started LDN, but I really

think it went as well as it did because of it. I also noticed during that week

that my RLS changed, my left leg wasn't feeling/doing the same thing. We also

got a 5 speed Saturn that busy week and I've been driving it the last 2 weeks.

Except for some weakness that I notice, it's like a new leg! I also noticed

that my BU wasn't as frequent, and in the last week I noticed I've been able to

keep it under control, go a lot longer, and even hold it if/when I've had to

(sometimes I just do anyway, to see). I still have the

tingles/spasms/buglikecrawlingfeeling in my left shoulder blade.. it seems to

be less frequent, but it's still there alright.

I have been getting more sleep though, taking naps when I feel the need to

rest. But I don't think the LDN is causing me fatigue, I think my body wants

the rest time so it can do some more healing.

It can't be a coincidence, otherwise the RLS & BU wouldn't have both suddenly

changed, I figure they'd have had their own timetable. I also don't think I

could have changed these symptoms just by THINKING the LDN would help... it

just DID! I don't feel like I'm healthy and wonderful and healed, but it's

been so much more manageable so far.

I haven't given any thought to skipping days though... is there a benefit

there?

----- Original Message -----

From: " massimo_ciabo " <massimo_ciabo@...>

<low dose naltrexone >

Sent: Wednesday, May 07, 2003 12:10

Subject: [low dose naltrexone] Dosage and Inttermittant therapy

> It appears clear that some people are starting addressing problems to

> an high dosage of LDN of 4.5 mg.

> I had a prescription from a doctor here in UK and he is suggesting to

> start with 3 mg at least for a month before upgrading dosage. He is

> also highlighting the fact that upgrading to an higher dosage should

> be closely monitored. Furthermore, my UK doctor tells me that taking

> 3 mg of LDN doesn't create problems for that initial month, however,

> when moving to 4.5 he is advising to undertake an intermittant

> therapy of 2 weeks on LDN followed by 3 days off in a cycle. He does

> inform me in the same documentation that Dr. Bihary does not equally

> advise this intermittent therapy.

> I am starting to suspect that upgrading the dose it is not a must and

> it might be person dependent....

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