Re: Naltrexone Has Been Compounded With Naltrexone

[Guest guest]

I read something like tat too, only it was morphine and low dose

naltrexone for severe pain......but I'll wait for the trials to end.

in the meantime I suggest staying away from the opiads until further

study.

Hugs, Sally

>

> There's a post on this cite that says mixing an opiod, e.g.,

Talwin, with

> Naltrexone is contraindicated and dangerous to your health. Then,

how would one

> explain this anomaly? Pain Therapeutics, Inc., a biotech company

in San

> Francisco (Nasdaq symbol PTIE) has developed a compound for

chronic pain which

> consists of both Naltrexone and Oxycodone. They are now in phase 3

clinical

> trials.....It's called Oxytrex. Does anyone care to comment of

this?

[Guest guest]

Someone on this cite said they were taking an opiod and then concurrently started naltrexone. According to this person, she had seizures and had to be hospitalized. I believe I've see other posts warning of mixing opiods with N. I think Dr. Bihari advises patients that they must be off of opiods before starting N. Maybe I misread these posts, but I don't think so. If I have misread the posts, please correct me. When I found the information about Oxytrex, which is in phase 3 clinical trials, I began to question the accuracy of these posts. There seems to be a conflict here.

Pain Therapeutics, Inc. the developer of Oxytrex, is very encouraged and excited by their breakthrough in the control of chronic pain. Based on their first two trials, they are claiming that naltrexone combined with oxycodone does not have the same side effects as taking oxycondone alone, side effects such as tolerance, constipation and addiction, etc. And, the dosage amount is very small. Also, the combination of the two offers significantly more pain protection than oxycondone alone. Pain Therapeutics refused to reveal the ratio of oxycondone to N. They feel quite strongly that it is definitely an innovation unlike anything that has ever been offered for the control of chronic pain. For about 40 million people in chronic pain (not acute), it may be a bonanza.

[Guest guest]

You are right, there have been such posts here, and I don't quite

understand it myself. As I understand it, naltrexone is an opiad

antagonist, and so, wipes out the effectiveness of the opiad. I

have never heard on any site, except here, that there are such side

effects such as seisures and death. I have heard of many studies,

including morphine and naltrexone togeather for pain management. So

I am also at a loss here, in understanding why this person would

have seisures after mixing an opiod with naltrexone. I think that

the opiod that this person was on may have caused the seisures and

may have had nothing to do with the naltrexone?

Dr Bahari states, that in order for the LDN to be effective in

raising the endorphine level and regulating the immune systemthat it

is counteractive to have opiods in your system. I don't know if he

has ever said that it would cause seisures or other life threatening

actions.

I would like to see some more feed back on this issue....perhaps Dr.

Bahari's patients here could ask him and post his answer. This is

an important issue for us and should be resolved. The fact that

there are studies being conducted on LDN and Opiods, contradicts

what we have heard from Dr. Bahari about mixing the two.

Thanks for your post Galaxyhal, and bringing this to our attention.

~Sally

galaxyhal@a... wrote:

> Someone on this cite said they were taking an opiod and then

concurrently

> started naltrexone. According to this person, she had seizures and

had to be

[Guest guest]

Hi:

So, if someone is on a painkiller with codeine, how long after they

stop the painkiller can they start/go back on LDN?

thanks in advance

best,

lea